Pramipex Er 3 Mg Tablet (10 Tab)

PRAMIPEX ER 3 MG TABLET by SUN PHARMA LABORATORIES LTD.

Name

• Brand Name: PRAMIPEX ER 3 MG TABLET
• Common Name: Pramipexole (extended-release)

Composition PRAMIPEX ER 3 MG TABLET contains 3 mg of Pramipexole as its active ingredient. Pramipexole is a dopamine agonist that works by mimicking the action of dopamine in the brain, a natural substance essential for controlling body movement.

Uses This medication is prescribed for adults to treat the symptoms of:

• Parkinson's Disease: It helps manage symptoms such as tremors, stiffness, slowed movement, and poor muscle control, thereby improving mobility and daily functioning.
• Restless Legs Syndrome (RLS) / Willis-Ekbom disease: It helps relieve the uncontrollable urge to move the legs, especially at night, and reduces associated discomfort.

Dosage and Administration PRAMIPEX ER 3 MG TABLET should be taken orally, usually once daily, with or without food, as advised by your doctor. Swallow the tablet whole; do not crush, break, or chew it, as this can affect the extended-release mechanism. For RLS, it is often recommended to take the medicine 2 to 3 hours before bedtime. Do not discontinue the medication suddenly without consulting your doctor, as it may worsen your condition or lead to withdrawal symptoms.

Side Effects

• Common Side Effects: Sleepiness (somnolence), nausea, constipation, dizziness, fatigue, hallucinations, dry mouth, muscle spasms, headache, vomiting, decreased appetite, weight loss, and peripheral oedema (leg swelling).
• Serious Side Effects: May include severe hallucinations, confusion, aggressive behavior, agitation, abnormal thoughts, changes in vision, uncontrolled body movements (dyskinesia), impulse control disorders (e.g., increased sex drive, compulsive gambling, overeating), and sudden onset of sleep during daily activities. Seek immediate medical attention if these occur.

Precautions

• Avoid driving or operating heavy machinery if you experience drowsiness, dizziness, or sudden onset of sleep.
• Alcohol consumption should be avoided as it can increase drowsiness and dizziness.
• Inform your doctor if you have kidney problems, low blood pressure (hypotension), or mental health conditions.
• Pregnant or breastfeeding individuals should consult their doctor, as safety data is limited and the medicine may reduce breast milk production.
• Rise slowly from sitting or lying positions to minimize dizziness due to a sudden drop in blood pressure (orthostatic hypotension).
• Not recommended for use in children below 18 years of age.
• Inform your doctor about all other medications you are taking, including supplements and herbal products, as interactions can occur.

Storage Store PRAMIPEX ER 3 MG TABLET in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep it out of reach and sight of children and pets.

Pramipex ER 3 mg Tablet (by SUN PHARMA LABORATORIES LTD.) is an extended-release medication containing pramipexole, primarily used to manage symptoms of Parkinson's disease and restless legs syndrome. Below are frequently asked questions regarding this medicine.

What is Pramipex ER 3 mg Tablet used for?

Pramipex ER 3 mg Tablet is used to treat the symptoms of Parkinson's disease, such as muscle spasms, tremors, stiffness, and poor muscle control. It is also prescribed for moderate to severe Willis-Ekbom disease (restless legs syndrome) in adults, helping to relieve the uncomfortable urge to move the legs, especially at night.

How does Pramipex ER 3 mg Tablet work?

This medicine contains pramipexole, which belongs to a class of drugs called dopamine agonists. It works by mimicking the action of dopamine, a natural chemical messenger in the brain essential for controlling body movement. By stimulating dopamine receptors in the brain, Pramipex ER 3 mg helps to trigger nerve impulses that control body movements, thereby alleviating symptoms of Parkinson's disease and restless legs syndrome.

What is the usual dosage for Pramipex ER 3 mg Tablet?

Pramipex ER 3 mg is an extended-release tablet that is typically taken once daily, with or without food. Taking it with food may help reduce nausea. It's important to swallow the tablet whole and not to chew, crush, or divide it. For Parkinson's disease, the starting dose is usually 0.375 mg once daily, which may be gradually increased by your doctor in increments, not more frequently than every 5 to 7 days, up to a maximum recommended dose of 4.5 mg per day. For restless legs syndrome, the starting dose is usually 0.125 mg once daily, taken 2 to 3 hours before bedtime, and can be adjusted up to a maximum of 0.5 mg daily. Always follow your doctor's specific instructions for dosage and administration.

What are the possible side effects of Pramipex ER 3 mg Tablet?

Common side effects can include sleepiness, nausea, constipation, dizziness, fatigue, dry mouth, muscle spasms, peripheral edema (leg swelling), confusion, increased urination, headache, trouble sleeping, and abnormal dreams. More serious side effects, though less common, can include hallucinations (seeing or hearing things that are not real), sudden onset of sleep (sleep attacks), a sudden drop in blood pressure when standing (orthostatic hypotension), and impulse control disorders (such as compulsive gambling, eating, or increased sex drive). If you experience any severe or persistent side effects, or notice unusual urges or behaviors, you should inform your doctor immediately.

Is Pramipex ER 3 mg Tablet safe during pregnancy or breastfeeding?

Pramipex ER 3 mg Tablet is generally not recommended during pregnancy, as there is limited human safety information and animal studies have shown potential harmful effects on the developing baby. Your doctor will assess the benefits and risks before prescribing it if you are pregnant or planning to become pregnant. It is also likely unsafe during breastfeeding. Pramipexole may pass into breast milk and could harm the baby, and it can also reduce breast milk production. If taking this medicine is unavoidable, breastfeeding should be stopped.

Can Pramipex ER 3 mg Tablet be taken with other medications?

You should inform your doctor about all prescription and over-the-counter medications, vitamins, herbal products, and supplements you are taking. Alcohol should be avoided as it can increase drowsiness and dizziness. Medications that block dopamine, such as metoclopramide and certain antipsychotics (e.g., chlorpromazine, haloperidol, olanzapine), can make Pramipex ER less effective or are contraindicated. Cimetidine can increase the levels of pramipexole in your body, so co-administration should be avoided. Other medications that cause drowsiness or increase dopamine effects should also be used with caution, as they may enhance side effects.

What precautions should be taken while on Pramipex ER 3 mg Tablet?

Do not stop taking this medication suddenly, as abrupt discontinuation can lead to withdrawal symptoms like fever, confusion, severe muscle stiffness, and anxiety. Your doctor will provide instructions for gradual dose reduction. Due to the potential for drowsiness, dizziness, or sudden sleep attacks, avoid driving or operating heavy machinery until you understand how the medication affects you. To prevent dizziness from low blood pressure, rise slowly when standing up from a sitting or lying position. If you have kidney problems, your doctor may need to adjust your dose. Pramipex ER is not recommended for individuals under 18 years of age.

What happens if a dose of Pramipex ER 3 mg Tablet is missed?

If you miss a dose, take it as soon as you remember, unless more than 12 hours have passed since your regularly scheduled time. If it has been more than 12 hours, skip the missed dose and take your next dose at the usual time. Do not take a double dose to make up for a missed one.

How should Pramipex ER 3 mg Tablet be stored?

Pramipex ER 3 mg Tablet should be stored in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep it out of reach and sight of children. The typical storage temperature is between 20°C to 25°C (68°F to 77°F).