Dapaturn M 5 Mg Tablet (10 Tab)

DAPATURN M 5 MG TABLET (10 TAB) by LUPIN LTD.

DAPATURN M 5 Tablet is an oral anti-diabetic medication manufactured by Lupin Ltd., prescribed for the management of Type 2 diabetes mellitus. It is designed to help control high blood sugar levels and may also reduce the risk of serious complications associated with diabetes, such as kidney damage, eye problems, nerve issues, and heart disease.

• Composition: Each film-coated tablet contains Dapagliflozin Propanediol Monohydrate equivalent to Dapagliflozin 5 mg and Metformin Hydrochloride 500 mg (Extended-release).

  • Dapagliflozin: This active ingredient is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It works by blocking the reabsorption of glucose in the kidneys, leading to increased excretion of excess glucose through urine, thereby lowering blood sugar levels.
  • Metformin: A biguanide, Metformin reduces glucose production in the liver, delays glucose absorption from the intestines, and enhances the body's sensitivity to insulin, improving glucose uptake and utilization by cells.

• Uses: DAPATURN M 5 Tablet is primarily used for the treatment of Type 2 diabetes mellitus in adults. It is used to improve glycemic control when diet and exercise alone are insufficient, and can be used in combination with other diabetes medications like insulin or GLP-1 receptor agonists. It also helps prevent heart disease and may reduce the risk of hospitalization due to heart failure in adults with Type 2 diabetes and cardiovascular disease or multiple cardiovascular risk factors.

• Dosage and Administration: DAPATURN M 5 Tablet should be taken orally with food, at the same time each day, as directed by a healthcare professional. The tablet should be swallowed whole and not chewed, crushed, or broken. The dosage and duration of treatment are determined by the doctor based on the patient's condition.

• Side Effects:

  • Common: Nausea, vomiting, diarrhea, headache, sore throat, nasal congestion (nasopharyngitis), runny nose, urinary tract infections, genital fungal infections, increased urination, dizziness, stomach pain or discomfort, flatulence, skin rash, and taste changes.
  • Serious: Dehydration, low blood glucose levels (hypoglycemia), lactic acidosis (symptoms include nausea, vomiting, stomach pain, muscle cramps, severe tiredness, difficulty breathing, dizziness, lightheadedness, reduced body temperature, low blood pressure), and kidney function impairment.

• Precautions:

  • Inform your doctor about any existing kidney or liver issues, urinary tract infections, heart conditions, or if you are taking diuretics.
  • Not recommended for Type 1 diabetes, severe kidney or liver disease, recent heart attack, heart failure, severe infection, or diabetic ketoacidosis.
  • Pregnant or breastfeeding women should consult their doctor before use.
  • Avoid excessive alcohol consumption as it may increase the risk of lactic acidosis.
  • Regular monitoring of blood sugar levels is recommended.
  • Do not discontinue the medication abruptly without consulting a doctor.

• Storage: Store below 30°C in a cool and dry place, away from sunlight, moisture, and out of the reach of children.

Here are frequently asked questions and their answers about DAPATURN M 5 MG TABLET (10 TAB) by LUPIN LTD.:

What is Dapaturn M 5 MG Tablet used for?

Dapaturn M 5 MG Tablet is primarily used in adults to manage Type 2 diabetes mellitus, in conjunction with diet and exercise. It is also prescribed to reduce the risk of hospitalization for heart failure in individuals with Type 2 diabetes and cardiovascular disease or multiple cardiovascular risk factors. Additionally, it helps lower the risk of cardiovascular death, hospitalization for heart failure, and worsening kidney disease in patients with chronic kidney disease or heart failure with reduced ejection fraction. This medication is not for treating Type 1 diabetes.

How does Dapaturn M 5 MG Tablet work?

This medicine contains two active ingredients: Dapagliflozin and Metformin. Dapagliflozin works in the kidneys by blocking a protein called SGLT2, which leads to the removal of excess glucose (sugar) from the body through urine, thereby lowering blood sugar levels. Metformin works by decreasing the production of glucose in the liver, reducing the absorption of sugar from the intestines, and improving the body's sensitivity to insulin, allowing it to use sugar more effectively.

What is the usual dosage for Dapaturn M 5 MG Tablet?

The dosage of Dapaturn M 5 MG Tablet is determined by your doctor based on your medical condition and response to treatment. It is typically taken once daily in the morning with food. The tablet should be swallowed whole and not crushed, cut, or chewed. The starting dose for Type 2 diabetes often includes Dapagliflozin 5 mg and Metformin 500 mg once daily. Your doctor may adjust the dose, but it usually should not exceed 10 mg of dapagliflozin and 2000 mg of metformin per day.

What are the possible side effects of Dapaturn M 5 MG Tablet?

Common side effects may include genital fungal infections (like yeast infections), urinary tract infections (UTIs), increased urination, headache, nausea, vomiting, diarrhea, runny or stuffy nose, sore throat, back pain, and dizziness.

Serious side effects that require immediate medical attention include allergic reactions (rash, hives, swelling of the face/lips/tongue/throat), dehydration (severe thirst, dry mouth, feeling faint, dark urine), diabetic ketoacidosis (increased thirst/urination, fatigue, fruity breath, stomach pain, nausea, vomiting), and lactic acidosis (unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, extreme weakness).

Is Dapaturn M 5 MG Tablet safe during pregnancy or breastfeeding?

Dapaturn M 5 MG Tablet is generally not recommended during pregnancy, especially during the second and third trimesters, as it may harm the unborn baby's kidneys. If you become pregnant while taking this medicine, you should discontinue it and consult your doctor immediately. Other diabetes medications, such as insulin and metformin alone, are often considered safer alternatives during pregnancy. Metformin can also cause changes in the menstrual cycle that may increase the chance of pregnancy, so discuss birth control options with your doctor.

For breastfeeding, this medication is also not recommended. While dapagliflozin is unlikely to pass into breast milk in significant amounts, there's a theoretical risk to the infant's developing kidney. Metformin does pass into breast milk in small amounts, but its effects on the nursing infant are not fully known, and caution is advised, especially for newborns and premature infants. Your doctor can discuss alternatives if you are breastfeeding.

Can Dapaturn M 5 MG Tablet be taken with other medications?

Yes, but caution is advised as it can interact with various medications. It is crucial to inform your doctor about all medicines, supplements, and herbal products you are currently taking. Taking Dapaturn M 5 MG Tablet with insulin or other diabetes medications like sulfonylureas can increase the risk of low blood sugar, and dose adjustments of those medications may be necessary. Diuretics ("water pills") can increase the risk of dehydration and low blood pressure when taken with this medicine. Alcohol, certain carbonic anhydrase inhibitors, and some medications that decrease metformin clearance (e.g., cimetidine, ranolazine) can increase the risk of lactic acidosis. You may also need to temporarily stop this medication before or during imaging procedures that use iodinated contrast agents.

What precautions should be taken while using Dapaturn M 5 MG Tablet?

Before starting Dapaturn M 5 MG Tablet, discuss your medical history with your doctor, especially if you have kidney or liver disease, heart failure, pancreatitis, a history of genital or urinary tract infections, dehydration, or low vitamin B12 levels. It is important to stay well-hydrated, especially in hot weather or if you experience fever, infection, vomiting, or diarrhea. Limit alcohol consumption as it can increase the risk of serious side effects like lactic acidosis and low blood sugar. Inform your doctor or dentist if you are scheduled for surgery or certain medical tests, as you may need to temporarily stop this medication. Regularly monitor your blood sugar levels and be aware of the symptoms of both low (hypoglycemia) and high (hyperglycemia) blood sugar. Always carry a source of quick sugar to treat low blood sugar. Long-term use of metformin can lead to low vitamin B12 levels, so your doctor may recommend monitoring or supplementation.

What happens if a dose of Dapaturn M 5 MG Tablet is missed?

If you miss a dose of Dapaturn M 5 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Dapaturn M 5 MG Tablet be stored?

Store Dapaturn M 5 MG Tablet in its original closed container at room temperature. Keep it away from excessive heat, moisture, and direct light. Do not store it in the bathroom. Ensure it is kept out of the reach of children.