Budoneb Pd Respules 2ml

BUDONEB PD RESPULES 2ML by EVONEXT HEALTHCARE DIV.

BUDONEB PD RESPULES 2ML is a medication designed for the maintenance treatment of respiratory conditions, delivered via nebulization. It contains a potent corticosteroid that works to reduce inflammation in the airways, making breathing easier.

Name

• Common Name: Budesonide Inhalation Suspension
• Brand Names: BUDONEB, Budoneb 0.5 Respule

Composition

• Active Ingredients: Budesonide (0.5 mg/2mL)
• Other Ingredients: Citric acid anhydrous, disodium edetate, polysorbate 80, sodium chloride, sodium citrate, water for injection.

Uses

BUDONEB PD RESPULES 2ML is primarily used for the prevention and long-term management of respiratory conditions.

• Asthma: It is prescribed as maintenance therapy to reduce airway inflammation, prevent asthma attacks (wheezing and shortness of breath), and improve overall breathing function. It is not intended to relieve sudden asthma attacks, for which a quick-relief inhaler should be used.
• Croup: It is also recommended for infants and children with croup (acute viral upper respiratory tract infection) when hospitalization is necessary.
• Chronic Obstructive Pulmonary Disease (COPD): Helps manage symptoms like breathlessness, chronic cough, and wheezing by reducing airway inflammation and improving lung capacity.

Dosage and Administration

BUDONEB is administered using a jet nebulizer equipped with a mouthpiece or mask, connected to an air compressor. The dosage is individualized and should be titrated to the lowest effective maintenance dose.

• Typical Guidance: The dose is usually given twice daily.
  • Children (1-6 years and older): 0.25 – 2 mg daily. For maintenance treatment of asthma, specifically children 12 months to 8 years of age, the dosage forms include 0.25 mg/2 mL, 0.5 mg/2 mL, and 1 mg/2 mL inhalation suspensions for nebulization.
  • Adults: 0.5 – 4 mg daily.
• Administration Notes:
  • Shake the contents gently before use.
  • Rinse the mouth and throat with water or brush teeth after each use to minimize the risk of throat irritation and oral fungal infections.
  • If using a face mask, ensure it fits tightly and wash the facial skin after use to prevent irritation.
  • The medicine should be used regularly for effectiveness, even if symptoms are not present.
  • It may take a few days to notice the effect, with maximum benefit often reached after a few weeks.
  • Do not mix with other medicines unless advised by a doctor.

Side Effects

Common Side Effects:

• Irritation in the throat, sore throat
• Difficulty swallowing
• Headache
• Indigestion, stomach pain, abdominal pain, nausea
• Cough, hoarseness
• Runny or stuffy nose
• Increased risk of infection

Serious Side Effects (Report to doctor immediately):

• Allergic reactions (skin rash, itching, hives, swelling of face, lips, tongue, or throat)
• Flu-like symptoms (fever, chills, muscle pain, cough, headache, or fatigue)
• White patches in the mouth or throat (thrush)
• Worsening wheezing or trouble breathing immediately after use (paradoxical bronchospasm)
• Eye problems (glaucoma or cataracts), requiring regular eye exams
• Weak bones (osteoporosis) with long-term use, especially at high doses
• Low adrenal gland function (nausea, vomiting, loss of appetite, unusual weakness or fatigue, dizziness)

Precautions

• Medical History: Inform your doctor if you have tuberculosis, any infections in your mouth or lungs, liver disease, bone problems, glaucoma, or immune system problems.
• Pregnancy and Breastfeeding: Consult your doctor; animal studies show harmful effects on the developing baby, and the drug may pass into breastmilk.
• Infections: May increase the risk of infections; avoid contact with people who have colds or flu. Preventative treatment may be needed if exposed to chickenpox or measles. Long-term users are at high risk for acquiring tuberculosis.
• Sudden Asthma Attacks: Do not use this medicine to relieve sudden asthma attacks; use a quick-relief inhaler instead.
• Growth in Children: May cause children to grow more slowly than normal.
• Interactions: Inform your doctor about all medicines, herbs, non-prescription drugs, or dietary supplements you use. Specific interactions can occur with certain antibiotics (clarithromycin, erythromycin, telithromycin), antivirals for HIV/hepatitis, certain antifungals (itraconazole, ketoconazole), and nefazodone.
• Smoking: Avoid smoking or exposure to smoke as it can worsen symptoms and reduce effectiveness.
• Surgical Procedures: Inform any doctor or dentist about your use of BUDONEB before surgery.

Storage

• Store below 30°C.
• Keep the unused respules in the foil pouch to protect them from light.
• Do not freeze or refrigerate.
• Once a foil pouch is opened, discard any unused respules after 2 weeks.
• Once an individual ampule is opened, it should be used immediately, and any remaining suspension discarded.

BUDONEB PD RESPULES 2ML contains Budesonide, a corticosteroid used to manage and prevent symptoms of asthma and other respiratory conditions. It is administered via a nebulizer, which turns the medicine into a fine mist for inhalation.

Here are some frequently asked questions about BUDONEB PD RESPULES 2ML:

What is BUDONEB PD RESPULES 2ML used for?

BUDONEB PD RESPULES 2ML is primarily used for the maintenance treatment of asthma and as a prophylactic therapy in children aged 12 months to 8 years. It helps prevent symptoms such as wheezing, breathlessness, and chest tightness. It is also used to treat croup in infants and children. It is not intended for the rapid relief of acute asthma attacks; a separate "rescue" inhaler should be used for sudden symptoms.

How does BUDONEB PD RESPULES 2ML work?

BUDONEB PD RESPULES 2ML contains Budesonide, an inhaled corticosteroid. It works by reducing inflammation and swelling in the airways of the lungs, which helps improve airflow and makes breathing easier.

What is the usual dosage for BUDONEB PD RESPULES 2ML?

The dosage of Budesonide is individualized based on the patient's condition and response to treatment. For asthma, administration can be once or twice daily. Common dosages available for nebulization are 0.25 mg/2 mL, 0.5 mg/2 mL, and 1 mg/2 mL. It's crucial to use the lowest effective dose to control asthma and not to exceed the prescribed amount.

What are the possible side effects of BUDONEB PD RESPULES 2ML?

Common side effects may include throat irritation, cough, hoarseness, runny or stuffy nose, and stomach pain. More serious side effects to report to your doctor immediately include signs of infection (like fever or chills), white patches in the mouth or throat (oral thrush), worsening breathing problems or wheezing immediately after use, vision problems (such as blurred vision or halos around lights), or unusual tiredness. Long-term use can also lead to decreased bone density.

Is BUDONEB PD RESPULES 2ML safe during pregnancy or breastfeeding?

For pregnancy, inhaled budesonide has not been shown to increase the risk of abnormalities, and managing asthma effectively during pregnancy is crucial. Experts generally recommend that individuals do not stop using inhaled corticosteroids like budesonide during pregnancy. In breastfeeding, budesonide passes into breast milk in very small amounts, and infant exposure is considered negligible. It should be used during breastfeeding only if prescribed by a doctor, who will weigh the benefits against potential risks.

Can BUDONEB PD RESPULES 2ML be taken with other medications?

Budesonide can generally be used with most other medicines. However, certain medications may increase the chance of side effects by affecting its metabolism. Inform your doctor or pharmacist if you are taking:

• Medicines for HIV (e.g., ritonavir, cobicistat).
• Other steroid-containing medicines (e.g., eczema creams, steroid tablets, other asthma inhalers).
• Antifungal medicines (e.g., ketoconazole, itraconazole, voriconazole).
• Certain antibiotics (e.g., clarithromycin, erythromycin, telithromycin).
• Nefazodone. Do not mix BUDONEB PD RESPULES 2ML with any other medications in the nebulizer.

What precautions should be taken while using BUDONEB PD RESPULES 2ML?

• Do not use it to treat sudden asthma attacks; use a quick-relief inhaler instead.
• Rinse your mouth with water and spit it out (do not swallow) after each dose to help prevent oral thrush and throat irritation. Wash your face if using a face mask to prevent skin irritation.
• Avoid exposure to individuals with infections like chickenpox or measles, as this medicine can weaken your immune system.
• Inform your doctor about any history of infections (tuberculosis, fungal, viral), eye conditions (glaucoma, cataracts), liver disease, or bone problems.
• Do not stop or change the dose without consulting your doctor, as sudden discontinuation, especially after long-term use, can lead to withdrawal symptoms or worsening of your condition.
• Ensure proper nebulizer technique; do not use an ultrasonic nebulizer.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should BUDONEB PD RESPULES 2ML be stored?

Store BUDONEB PD RESPULES 2ML upright at room temperature, between 68°F to 77°F (20°C to 25°C), and protect it from light. Keep individual ampules in their foil envelope until ready to use. Once an ampule is opened, it should be used right away. Discard any unused ampules two weeks after opening the foil envelope. Do not refrigerate or freeze the medication.