Cipzen D Tab (10 Tab)

CIPZEN D TAB (10 TAB) by CIPLA LTD.(GENERIC DIVISION)

CIPZEN D TAB is a combination medication designed for the short-term relief of pain, inflammation, and swelling in adults. It is manufactured by Cipla Ltd. (Generic Division) and typically comes in strips of 10 tablets.

Composition

CIPZEN D TAB contains two active ingredients:

• Diclofenac (50 mg): A non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the release of chemical messengers responsible for pain and inflammation.
• Serratiopeptidase (10 mg): A proteolytic enzyme that helps reduce inflammation by breaking down abnormal proteins at the site of inflammation and promoting healing.

Uses

CIPZEN D TAB is prescribed for various acute pain and inflammatory conditions, including:

• Rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.
• Muscle pain, back pain, toothache, earache, and throat pain.
• Menstrual pain.
• Post-surgical and post-traumatic inflammation and pain.
• Mild to moderate migraine headaches.

Dosage and Administration

• CIPZEN D TAB should be taken exactly as directed by your doctor.
• Swallow the tablet whole with a glass of water; do not cut, break, or chew it.
• It can be taken with or after food to minimize stomach discomfort, though some sources suggest preferably before meals.
• Take the medicine at a fixed time each day for optimal results.
• Do not exceed the prescribed dose or duration of treatment.
• For adults, a typical dosage of diclofenac ranges from 75 mg to 150 mg daily, divided into two or three doses.
• This medicine is generally not recommended for children below 18 years of age and should be used with caution in adolescents above 14 years. Elderly patients may require a lower effective dose.

Side Effects

Common side effects may include:

• Nausea, vomiting, heartburn, stomach pain, indigestion, diarrhea, and loss of appetite.
• Headache, dizziness, giddiness, sleepiness, and drowsiness.

Serious side effects, though less common, require immediate medical attention:

• Gastrointestinal bleeding, ulcers, or perforation, which can be fatal.
• Severe allergic reactions such as skin rashes, itching, swelling of the face, lips, tongue, difficulty breathing, or wheezing.
• Signs of liver problems like yellowing of the skin or eyes.
• Kidney problems or fluid retention.
• Cardiovascular thrombotic events, heart attack, or stroke.

Precautions

• Contraindications: Do not take CIPZEN D TAB if you are allergic to diclofenac, serratiopeptidase, aspirin, ibuprofen, or other NSAIDs. It is also contraindicated in patients with active stomach ulcers, gastrointestinal bleeding, severe heart, kidney, or liver failure, or those who have recently undergone coronary artery bypass graft (CABG) surgery.
• Pregnancy and Breastfeeding: It is not recommended during the last trimester of pregnancy due to risks to the fetus and mother. Consult your doctor if you are pregnant, planning to conceive, or breastfeeding.
• Medical Conditions: Use with caution in patients with a history of liver or kidney problems, high blood pressure, heart disease, asthma, or bleeding disorders. Regular alcohol consumption can increase the risk of serious liver damage.
• Drug Interactions: Inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements, as CIPZEN D TAB can interact with blood thinners, diuretics, certain antidepressants, and other NSAIDs.
• Driving and Machinery: This medicine may cause dizziness or drowsiness; avoid driving or operating heavy machinery if you experience these effects.
• Long-term Use: Prolonged use may require regular monitoring of kidney function, liver function, and blood counts.

Storage

Store CIPZEN D TAB at room temperature (20-25°C), away from moisture and heat. Keep it in its original packaging and out of the reach of children and pets. Do not use the medicine after its expiry date.

What is CIPZEN D TAB used for?

CIPZEN D TAB is a combination medication used for the short-term relief of pain, inflammation, and swelling. It is prescribed for various conditions, including arthritis (such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis), muscle and joint injuries, dental pain, back pain, earache, throat pain, menstrual pain, and post-surgical recovery.

How does CIPZEN D TAB work?

CIPZEN D TAB contains two active ingredients: Diclofenac and Serratiopeptidase. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the production of certain chemical messengers in the body, called prostaglandins, which are responsible for pain and inflammation. Serratiopeptidase is an enzyme that helps reduce inflammation and swelling by breaking down abnormal proteins at the site of inflammation, thereby promoting healing.

What is the usual dosage for CIPZEN D TAB?

The usual adult dosage for CIPZEN D TAB is typically 75 mg to 150 mg daily, divided into two or three doses, as directed by a doctor. The maximum recommended daily dose of diclofenac sodium is 150 mg. It should be taken with or after food to minimize stomach discomfort. Tablets should be swallowed whole with water and should not be crushed or chewed.

What are the possible side effects of CIPZEN D TAB?

Common side effects may include stomach pain, indigestion, heartburn, nausea, vomiting, diarrhea, headache, dizziness, and loss of appetite. More serious, though less common, side effects can include gastrointestinal bleeding or ulcers, severe allergic reactions (like skin rash, itching, swelling, or difficulty breathing), wheezing, shortness of breath, and issues with liver or kidney function. If any severe or persistent side effects occur, seek immediate medical attention.

Is CIPZEN D TAB safe during pregnancy or breastfeeding?

CIPZEN D TAB is generally not recommended during the third trimester of pregnancy due to potential risks to the fetus, including premature closure of a fetal blood vessel (ductus arteriosus) and other complications. During the first and second trimesters, it should only be used if clearly necessary and prescribed by a doctor. It is also not recommended for use during breastfeeding, as diclofenac can pass into breast milk and may cause undesirable effects in the infant.

Can CIPZEN D TAB be taken with other medications?

CIPZEN D TAB can interact with several other medications. It should be used with caution, or avoided, if you are taking blood thinners (anticoagulants like warfarin or aspirin), other NSAIDs (including ibuprofen or COX-2 inhibitors), diuretics, antihypertensive agents, lithium, digoxin, methotrexate, ciclosporin, mifepristone, quinolone antimicrobials, or phenytoin. Always inform your doctor about all medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.

What precautions should be taken while using CIPZEN D TAB?

Do not take CIPZEN D TAB if you are allergic to diclofenac, aspirin, ibuprofen, other NSAIDs, or serratiopeptidase. Exercise caution if you have a history of stomach ulcers, gastrointestinal bleeding, heart disease (including heart failure or high blood pressure), kidney or liver problems, asthma, or fluid retention. Alcohol consumption should be avoided while taking this medicine as it may increase the risk of stomach bleeding and liver problems. It is generally not suitable for children under 12 years of age.

What should I do if I miss a dose of CIPZEN D TAB?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the forgotten one.

How should CIPZEN D TAB be stored?

Store CIPZEN D TAB in its original packaging in a cool, dry place, typically below 25°C. Keep it protected from moisture and light, and ensure it is kept out of the sight and reach of children.

Can CIPZEN D TAB cause dizziness or affect driving?

Yes, CIPZEN D TAB may cause side effects such as dizziness, giddiness, sleepiness, or drowsiness in some individuals. If you experience any of these symptoms, it is advisable to avoid driving or operating machinery.