Yees D Capsule

YEES D CAPSULE

YEES D CAPSULE is a prescription medication manufactured by Alkem Laboratories Ltd. It is a combination drug used to manage various gastrointestinal conditions related to acidity and digestive motility.

Composition

Each YEES D CAPSULE typically contains a fixed-dose combination of:

• Domperidone: 30mg
• Esomeprazole: 40mg

Esomeprazole functions as a proton pump inhibitor (PPI), reducing the production of stomach acid. Domperidone is a prokinetic agent and dopamine antagonist that enhances the movement of the stomach and intestines, facilitating the passage of food and reducing reflux.

Uses

YEES D CAPSULE is primarily prescribed for adults to treat:

• Gastroesophageal Reflux Disease (GERD) / Acid Reflux: Especially when GERD does not adequately respond to esomeprazole alone. It alleviates symptoms like heartburn, stomach pain, and irritation.
• Peptic Ulcers: Including stomach ulcers and duodenal ulcers.
• Zollinger-Ellison Syndrome: A condition causing excessive stomach acid production.
• Indigestion, Nausea, Vomiting, Bloating, Belching, and Upper Abdominal Pain: By neutralizing stomach acid and promoting gas passage.

Dosage and Administration

• YEES D CAPSULE should be taken orally, typically once daily, or as directed by a healthcare professional.
• It must be swallowed whole with water, without chewing, crushing, or breaking the capsule.
• For optimal effectiveness, it is advised to take the capsule on an empty stomach, preferably 30 minutes to 1 hour before a meal.
• The dosage and duration of treatment are determined by the doctor based on the patient's condition and response to the medication.

Side Effects

Common side effects may include:

• Diarrhea
• Flatulence
• Stomach pain
• Dry mouth
• Headache
• Nausea and vomiting
• Constipation
• Benign polyps in the stomach

Serious but rare side effects can include severe allergic reactions, signs of liver problems, severe skin reactions, chest pain, irregular heartbeat, difficulty breathing, feeling faint, and fits. Long-term use may lead to deficiencies in magnesium and vitamin B12, and may affect bone health.

Precautions

• Inform your doctor about any existing liver, kidney, or heart conditions, or if you have a history of intestinal blockage, stomach bleeding, prolactinoma, or weak bones.
• Caution is advised regarding alcohol consumption as it may increase drowsiness and stomach acid production.
• YEES D CAPSULE may cause dizziness or drowsiness; therefore, caution is recommended when driving or operating machinery until you know how the medicine affects you.
• Pregnant or breastfeeding women should consult their doctor before use, as it may not be recommended or requires careful consideration.
• Inform your doctor about all other medications you are taking, as some drugs can interact with YEES D CAPSULE.
• Not recommended for use in children.
• Report any persistent or worsening symptoms like unexplained weight loss, difficulty swallowing, vomiting blood, or black stools to your doctor.

Storage

Store YEES D CAPSULE below 25°C in a clean and dry place, protected from direct sunlight, moisture, and heat. Keep this medicine out of the sight and reach of children and pets. Ensure the original container is tightly closed.

Frequently Asked Questions about YEES D CAPSULE

What is YEES D CAPSULE used for?

YEES D CAPSULE is primarily used to treat gastroesophageal reflux disease (GERD), also known as acid reflux, especially when it does not respond to esomeprazole medicine alone. It helps alleviate symptoms such as heartburn, acidity, stomach pain, irritation, bloating, nausea, vomiting, belching, and upper abdominal pain. It is also prescribed for stomach ulcers and Zollinger-Ellison syndrome.

How does YEES D CAPSULE work?

YEES D CAPSULE contains two active ingredients: Domperidone and Esomeprazole. Domperidone is a prokinetic that works by increasing the movement and contractions of the stomach and intestines, helping food pass more easily through the digestive tract and reducing nausea and vomiting. Esomeprazole is a proton pump inhibitor (PPI) that reduces the production of stomach acid by blocking an enzyme responsible for acid secretion in the stomach lining.

What is the usual dosage for YEES D CAPSULE?

The dosage of YEES D CAPSULE should be strictly as prescribed by your doctor. It is typically taken orally at least 30 minutes to 1 hour before meals, swallowed whole with water. Do not chew or crush the capsule. The dosage may vary depending on the severity of your symptoms and how you respond to the medicine.

What are the possible side effects of YEES D CAPSULE?

Common side effects include diarrhea, flatulence, stomach pain, dry mouth, and headache. Less common or rare side effects can include dizziness, drowsiness, skin rash, weakness, cough, rhinitis, insomnia, breast pain, confusion, depression, edema, blurred vision, stomatitis, and chest pain. In rare cases, domperidone may cause heart rhythm problems, particularly in older adults or those with existing heart conditions. Long-term use may affect magnesium and vitamin B12 levels and bone health. If any side effects persist or worsen, consult your doctor.

Is YEES D CAPSULE safe during pregnancy or breastfeeding?

Pregnancy: YEES D CAPSULE should be used with caution during pregnancy, and only if considered necessary by a physician, as there is limited information about its safety in human pregnancy. Always inform your doctor if you are pregnant or planning to conceive before taking this medication.

Breastfeeding: YEES D CAPSULE passes into breast milk in small amounts and might affect the baby. It is generally advised to consult your doctor if you are breastfeeding, as some sources suggest it may be unsafe during breastfeeding.

Can YEES D CAPSULE be taken with other medications?

YEES D CAPSULE can interact with several medications. It is important to inform your doctor about all medicines you are currently taking, including over-the-counter drugs and herbal supplements. Potential interactions include:

• Antiretrovirals (e.g., ritonavir, atazanavir)
• Anticoagulants (e.g., clopidogrel)
• Immunosuppressants (e.g., tacrolimus)
• Anti-tubercular medications (e.g., rifampin)
• Antifungal medications (e.g., ketoconazole, fluconazole)
• Antibiotics (e.g., clarithromycin, erythromycin)
• Antidepressants (e.g., fluoxetine, citalopram)
• Anti-anxiety medications (e.g., diazepam, lorazepam)
• Medicines that affect heart muscle contraction (QT prolongation).
• Digoxin (for heart failure) and disopyramide (for irregular heartbeats).
• Concomitant use with diazepam (for psychiatric illness) or phenytoin (for fits) is generally not recommended as it may increase their side effects.

What precautions should be taken while taking YEES D CAPSULE?

• Inform your doctor about any pre-existing conditions, especially liver, kidney, or heart problems, any blockage or tear in the intestine, bleeding in the digestive system, weak bones, pituitary gland tumors, or severe heart conditions.
• Avoid consuming alcohol, as it can enhance drowsiness and increase stomach acid production.
• This medicine may cause dizziness and drowsiness, so avoid driving or operating heavy machinery until you know how it affects you.
• For optimal results, continue taking the medicine for the period prescribed by your doctor.
• Long-term use may require monitoring of magnesium and vitamin B12 levels, and bone health.
• Seek medical help if you experience persistent diarrhea, as prolonged use increases the risk of Clostridium difficile-associated diarrhea.

What happens if a dose of YEES D CAPSULE is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should YEES D CAPSULE be stored?

YEES D CAPSULE should be stored below 25°C or at room temperature, in a clean and dry place. Protect it from direct sunlight, moisture, and heat. Keep this medicine out of the sight and reach of children and pets.