Korandil 5 Mg Tablet (10 Tab)

KORANDIL 5 MG TABLET

KORANDIL 5 MG TABLET is a medication manufactured by SUN PHARMA LABORATORIES LTD., primarily used in the management of heart conditions.

• Name:

  • Brand Name: KORANDIL 5 MG TABLET
  • Common Name: Nicorandil

• Composition:

  • Each tablet contains 5 mg of Nicorandil as the active ingredient. Nicorandil is a vasodilator that works by relaxing and widening blood vessels, including coronary arteries. It acts as both a nitrate and a potassium channel opener. This action increases blood flow and oxygen supply to the heart muscle, while also reducing the heart's workload.

• Uses: KORANDIL 5 MG TABLET is prescribed for the following medical conditions:

  • Prevention and treatment of angina pectoris (chest pain caused by reduced blood flow to the heart).
  • Management of heart failure.
  • Improvement of blood flow to the heart in patients with coronary artery disease.
  • Adjunct therapy in patients with heart conditions requiring vasodilation.

• Dosage and Administration:

  • KORANDIL 5 MG TABLET should be taken exactly as prescribed by a doctor.
  • It can be taken with or without food, but it is often recommended to take it at about the same time(s) each day to maintain consistent medication levels.
  • The tablet should be swallowed whole with water; it should not be chewed, crushed, or broken.
  • The usual starting dose for adults is typically 10 mg orally twice daily, which may be adjusted by a healthcare professional based on the individual's response to treatment, not exceeding 20 mg twice daily. Do not stop taking it without consulting your doctor, as sudden withdrawal can cause chest pain to return.

• Side Effects: Common side effects may include:

  • Headache (especially during the first few days of treatment, usually improving within a week).
  • Dizziness or weakness.
  • Flushing (a sense of warmth in the face, ears, neck, and trunk).
  • Nausea and vomiting.
  • Low blood pressure.
  • Very fast, forceful or uneven heartbeat (palpitations).

  Serious side effects or allergic reactions require immediate medical attention. Rarely, it can cause gastrointestinal ulcers or an increase in potassium levels (hyperkalaemia).

• Precautions:

  • Contraindications: Avoid using if allergic to nicorandil or any other ingredients. It is not suitable for patients with severe low blood pressure (hypotension), cardiogenic shock, left ventricular failure with low filling pressure, cardiac decompensation, or pulmonary edema.
  • Drug Interactions: Do not take KORANDIL 5 MG TABLET with medications for erectile dysfunction (e.g., sildenafil, tadalafil, vardenafil) or medicines to treat pulmonary hypertension (e.g., riociguat), as this can cause a serious drop in blood pressure.
  • Alcohol: Alcohol consumption is generally unsafe with KORANDIL 5 MG TABLET, as it can increase dizziness and the risk of low blood pressure.
  • Driving/Operating Machinery: KORANDIL 5 MG TABLET may cause dizziness or sleepiness, so caution is advised when driving or performing tasks requiring concentration until you know how the medicine affects you.
  • Pregnancy and Breastfeeding: Generally not recommended during pregnancy or breastfeeding; consult a doctor.
  • Pre-existing Conditions: Inform your doctor if you have a history of low blood pressure, heart failure, or gastrointestinal disorders.

• Storage:

  • Store KORANDIL 5 MG TABLET in a cool, dry place.
  • Protect from direct sunlight and moisture.
  • Keep out of reach and sight of children and pets.
  • Some sources indicate it should be stored in cold places at 2ºC to 8ºC (cold chain).

KORANDIL 5 MG TABLET by SUN PHARMA LABORATORIES LTD.

What is Korandil 5 MG Tablet used for?

Korandil 5 MG Tablet, containing Nicorandil, is primarily used to prevent and treat angina pectoris, a type of chest pain caused by reduced blood flow and oxygen to the heart muscle. It is often prescribed when other heart medications are not suitable or haven't been effective. This medication helps reduce the frequency and severity of angina attacks and can improve exercise capacity in patients with angina.

How does Korandil 5 MG Tablet work?

Korandil 5 MG Tablet works through two main mechanisms. It activates ATP-sensitive potassium channels in vascular smooth muscles, causing them to relax and widen. This reduces peripheral resistance and the heart's workload. Additionally, it acts like nitrates by releasing nitric oxide, which stimulates an enzyme to boost cGMP levels, leading to the vasodilation of coronary arteries and systemic veins. This dual action improves blood flow and oxygen supply to the heart and reduces its workload.

What is the usual dosage for Korandil 5 MG Tablet?

The usual starting dose for adults is typically 10 mg (which might be two 5 mg tablets) taken orally twice daily. However, if headaches are a common issue, a smaller starting dose of 5 mg twice a day might be prescribed, which can be increased after about a week. The exact dosage and frequency will be determined by your doctor based on your medical condition and response to treatment. It should be swallowed whole with water, with or without food, and taken regularly at approximately the same time(s) each day. Do not stop taking it abruptly without consulting your doctor, as sudden withdrawal may worsen angina symptoms.

What are the possible side effects of Korandil 5 MG Tablet?

Common side effects include headache (especially during the first few days of treatment), dizziness, flushing (a sense of warmth in the face, ears, neck, and trunk), nausea, vomiting, weakness, and fatigue. These side effects usually improve within a week. If any side effects are severe or persistent, it's important to consult your doctor. More serious, but less common, side effects can include low blood pressure.

Is Korandil 5 MG Tablet safe during pregnancy or breastfeeding?

Korandil 5 MG Tablet is generally not recommended for use during pregnancy as its effects are unknown or may be unsafe based on animal studies. For breastfeeding mothers, caution is advised as it is considered probably unsafe or may cause serious side effects, so consulting a doctor is crucial to discuss the risks and benefits.

Can Korandil 5 MG Tablet be taken with other medications?

Korandil 5 MG Tablet can interact with several medications. It should not be taken with vasodilating medicines like sildenafil or tadalafil (used for erectile dysfunction) or riociguat (used for lung and heart diseases) as this can lead to a severe drop in blood pressure. Taking it with organic nitrates (like nitroglycerin) or other anti-hypertensives may also increase the risk of low blood pressure. Caution is advised with painkillers like acetylsalicylic acid, naproxen, or ibuprofen, as it may increase the risk of gastrointestinal complications. It's crucial to inform your doctor about all medicines, including herbal, vitamins, and mineral supplements, before starting Korandil 5 MG Tablet.

What precautions should be taken while using Korandil 5 MG Tablet?

Patients with low blood pressure, left ventricular dysfunction, or a history of serious ventricular arrhythmias should use Korandil 5 MG Tablet cautiously. It can cause dizziness or sleepiness, so avoid driving or operating heavy machinery until you know how it affects you. Alcohol consumption should be avoided as it can increase dizziness and significantly lower blood pressure. Inform your doctor if you have liver or kidney problems. Also, avoid salt substitutes high in potassium, as this medicine can increase potassium levels.

What happens if a dose of Korandil 5 MG Tablet is missed?

If you miss a dose of Korandil 5 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Korandil 5 MG Tablet be stored?

Korandil 5 MG Tablet should be stored at room temperature, typically between 15-30°C. It should be kept protected from direct light and moisture to maintain its effectiveness. Always store the medicine out of sight and reach of children. Some sources also mention storing it below 25°C or in a refrigerator (2-8°C), protected from moisture and heat.