Sevista 60 Mg Tablet

SEVISTA 60 MG TABLET

Sevista 60 mg Tablet, manufactured by Torrent Pharmaceuticals Ltd., is a non-hormonal and non-steroidal medication primarily used as an oral contraceptive. It also serves a significant role in managing certain gynecological conditions.

• Name:
  • Common Name: Sevista 60 mg Tablet
  • Brand Name: Sevista
• Composition:
  • Active Ingredient: Ormeloxifene 60 mg (also known as Centchroman)
  • Sevista is a selective estrogen receptor modulator (SERM).
• Uses:
  • Contraception: Primarily used to prevent unintended pregnancy by inhibiting the implantation of a fertilized egg onto the uterine wall.
  • Dysfunctional Uterine Bleeding (DUB): Prescribed to manage abnormal vaginal bleeding in women of reproductive age who have not yet reached menopause. It helps regulate menstrual cycles and alleviate related symptoms.
• Dosage and Administration:
  • Sevista 60 mg Tablet is generally taken orally once a week.
  • For contraception, the usual dosage is one 60 mg tablet once weekly.
  • For dysfunctional uterine bleeding, an initial regimen may involve one 60 mg tablet twice weekly for the first 12 weeks, followed by one 60 mg tablet once weekly.
  • It can be taken with or without food.
  • Swallow the tablet whole with a glass of water; do not crush, break, or chew it.
  • For optimal effectiveness, it is recommended to take the medicine at the same time each day/week.
  • It is advisable to use condoms for the first three months when initiating Sevista 60 mg Tablet for contraception.
• Side Effects:
  • Common: Irregular or delayed periods, menstrual irregularities, acne, water retention, breast tenderness, nausea, headache, dizziness, and weight gain.
  • Serious (Rare): Allergic reactions, difficulty breathing, or irregular heartbeat. Seek immediate medical attention if these occur.
• Precautions:
  • Sevista 60 mg Tablet is contraindicated during pregnancy as it cannot terminate an existing pregnancy and is not an abortion pill. Discontinue use if pregnancy occurs.
  • Caution is advised in breastfeeding mothers, as the medicine may pass into breast milk.
  • Not recommended for children under 16 years of age.
  • Use with caution in individuals with liver diseases (including a history of jaundice) or kidney disease; dose adjustments may be necessary.
  • Avoid if allergic to Ormeloxifene or any other ingredients.
  • Patients with tuberculosis, chronic cervicitis/hyperplasia, or unexplained vaginal bleeding should avoid this medication.
  • Inform your doctor about all other medications you are taking, as some drugs can interact with Sevista 60 mg Tablet.
  • Do not exceed the prescribed dosage, as an overdose may increase the risk of severe cardiovascular adverse effects.
• Storage:
  • Store Sevista 60 mg Tablet at room temperature, ideally between 15 to 25 degrees Celsius (68°F and 77°F).
  • Keep it away from direct sunlight, heat, and moisture.
  • Always keep the medicine in its original packaging and out of the sight and reach of children and pets.

What is Sevista 60 MG Tablet used for?

Sevista 60 MG Tablet is primarily used as an oral contraceptive to prevent pregnancy. It is also prescribed to manage dysfunctional uterine bleeding (DUB) in premenopausal women, a condition that disrupts the normal menstrual cycle. Additionally, it helps regulate menstrual cycles and provides relief from associated symptoms.

How does Sevista 60 MG Tablet work?

Sevista 60 MG Tablet contains Ormeloxifene, which is a non-hormonal, non-steroidal selective estrogen receptor modulator (SERM). It works by preventing the implantation of a fertilized egg in the uterus and by altering the uterine lining, making it unsuitable for pregnancy. It also modulates estrogen receptors in the reproductive system, causing an asynchrony between ovulation and the development of the uterine lining.

What is the usual dosage for Sevista 60 MG Tablet?

For contraception, the typical dosage is one 60 mg tablet taken once a week. For the initial 12 weeks of contraception, some doctors may recommend taking it twice a week (e.g., Sunday and Wednesday), followed by once a week from the 13th week onwards.

For dysfunctional uterine bleeding, the common initial dosage is one 60 mg tablet twice weekly for the first 12 weeks, which is then adjusted to one 60 mg tablet once weekly.

The tablet should be swallowed whole with water, and should not be chewed, crushed, or broken. It can be taken with or without food. Always follow your doctor's specific instructions regarding dosage and frequency.

What are the possible side effects of Sevista 60 MG Tablet?

Common side effects may include delayed or missed periods, menstrual irregularities, nausea, headache, dizziness, breast tenderness, and weight gain. Other reported side effects can include acne, water retention, abdominal pain, enlarged ovary, absence of menstrual periods, pain during periods, and allergic skin rash. Most side effects are temporary and often resolve as your body adjusts to the medication. If any side effects persist or worsen, consult your doctor.

Is Sevista 60 MG Tablet safe during pregnancy or breastfeeding?

Pregnancy: Sevista 60 MG Tablet is not recommended for use during pregnancy as it has contraceptive effects and can cause severe side effects. It is not an abortion pill and cannot terminate an existing pregnancy. If you become pregnant while taking this medicine, discontinue use immediately and consult your doctor.

Breastfeeding: Sevista 60 MG Tablet is generally considered safe for breastfeeding mothers, as it does not appear to harm breastfed infants. However, it is advisable to use it with caution and only after consulting your doctor, as a small amount of the medication may pass into breast milk.

Can Sevista 60 MG Tablet be taken with other medications?

Sevista 60 MG Tablet can interact with certain medications. It is crucial to inform your doctor about all prescription and over-the-counter medicines, vitamins, and herbal supplements you are taking.

Potential interactions include:

• Antacids and proton pump inhibitors (e.g., omeprazole, pantoprazole) may decrease its absorption.
• Certain antibiotics (e.g., rifampicin, ciprofloxacin, cefixime, metronidazole, tetracycline) may reduce its effectiveness.
• Blood pressure medications (e.g., amlodipine, atenolol).
• Theophylline (used for asthma).
• Diabetes medications (e.g., metformin, pioglitazone, glibenclamide).
• It is not recommended with estrogen-containing medications (like other oral contraceptives or hormone replacement therapy) or other selective estrogen receptor modulators (SERMs) such as tamoxifen or raloxifene.

What precautions should be taken while using Sevista 60 MG Tablet?

• Do not take Sevista 60 MG Tablet if you are allergic to Ormeloxifene or any other ingredients in the tablet.
• Caution is advised if you have liver problems (e.g., jaundice, severe hepatic dysfunction) or kidney problems; in severe cases, its use may not be recommended.
• It is not suitable for women with hormone-sensitive cancers, unexplained abnormal vaginal bleeding, tuberculosis, chronic cervicitis/hyperplasia, or Polycystic Ovary Syndrome (PCOS).
• Sevista 60 MG Tablet is not recommended for children younger than 16 years of age.
• When starting Sevista for contraception, it is advised to use additional non-hormonal contraception (like condoms) for the first three months.
• Limit alcohol consumption while on this medication.

What happens if a dose of Sevista 60 MG Tablet is missed?

For contraception: If you miss a dose, take it as soon as you remember. If you have missed it by 1 to 2 days (but less than 7 days), continue your usual schedule and use a backup method of contraception (such as condoms) until your next menstrual period begins. If you have missed more than 7 days, you should restart the schedule as if you are a new user (twice a week for 3 months, then once a week).

For other conditions (e.g., dysfunctional uterine bleeding): Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

How should Sevista 60 MG Tablet be stored?

Sevista 60 MG Tablet should be stored at room temperature, typically between 15 to 25 degrees Celsius (68 to 77 degrees Fahrenheit). Keep the medicine away from direct sunlight, heat, and moisture. Always store it in its original packaging and ensure it is kept out of reach of children and pets. Do not use the medicine beyond its expiry date.