GLOTRET 5 MG TABLET

GLOTRET 5 MG TABLET is a medication manufactured by GLOWDERMA LAB PVT. LTD., primarily used for the treatment of severe acne.

• Name

  • Common Name: Isotretinoin
  • Brand Name: GLOTRET 5 MG TABLET, Glotret-5 Tablet

• Composition

  • Active Ingredient: Isotretinoin 5 mg

• Uses GLOTRET 5 MG TABLET is prescribed for severe forms of acne, specifically nodular or cystic acne, that have not responded to other treatments, including antibiotics. It works by reducing the production of sebum (natural skin oil), killing acne-causing bacteria, preventing clogged pores, and decreasing inflammation.

• Dosage and Administration This medicine should be taken exactly as prescribed by your doctor. It is typically taken orally with food, preferably at the same time each day, to maximize its effectiveness. The tablet should be swallowed whole and not chewed, crushed, or broken. Improvement in symptoms may take a few weeks, and it is important to continue the treatment as directed.

• Side Effects Common side effects include:

  • Dry skin, chapped lips, dry eyes
  • Rash
  • Increased liver enzymes
  • Nosebleeds
  • Muscle or joint pain (especially in children and teenagers)
  • Headache
  • Increased sun sensitivity and skin fragility

• Precautions

  • Pregnancy: GLOTRET 5 MG TABLET is highly unsafe during pregnancy as it can cause severe birth defects. Women of childbearing potential must use effective contraception during treatment and for at least one month after stopping the medication.
  • Breastfeeding: It is generally considered unsafe to use during breastfeeding.
  • Alcohol: Caution is advised with alcohol consumption as it may increase the risk of liver damage.
  • Sun Exposure: Limit sun exposure and use sunscreen or protective clothing as the medicine increases sun sensitivity.
  • Cosmetic Procedures: Avoid waxing or laser treatments during and for at least 6 months after treatment, as the skin may become more fragile.
  • Other Conditions: Use with caution in patients with kidney disease. It is contraindicated in individuals with liver or pancreas problems, high blood lipid levels, abnormal vitamin A levels, or an allergy to isotretinoin.
  • Drug Interactions: Avoid concomitant use with Vitamin A supplements and certain antibiotics (e.g., minocycline, doxycycline). Consult a doctor if taking phenytoin or steroids.
  • Children: Not recommended for children under 12 years of age.
  • Driving: May affect night vision, drowsiness, or dizziness, so exercise caution when driving or operating machinery.
  • Blood Donation: Do not donate blood during treatment and for at least one month after treatment.

• Storage Store in a cool, dry place away from direct sunlight and out of the reach of children. It should be stored at temperatures between 10ºC to 25ºC or below 30ºC.

GLOTRET 5 MG TABLET FAQs

What is GLOTRET 5 MG TABLET used for?

GLOTRET 5 MG TABLET is primarily used to treat severe forms of acne, such as nodular or cystic acne, especially when other treatments like antibiotics have not been effective. It is also used for acne prone to permanent scarring.

How does GLOTRET 5 MG TABLET work?

GLOTRET 5 MG TABLET contains Isotretinoin, which is a derivative of vitamin A. It works by targeting the root causes of severe acne by reducing the production of excess oil (sebum) in the skin. This action helps prevent pores from becoming clogged, reduces the growth of acne-causing bacteria, and decreases inflammation (redness and swelling). It also promotes the turnover of skin cells to prevent new acne lesions.

What is the usual dosage of GLOTRET 5 MG TABLET?

The dosage and duration of GLOTRET 5 MG TABLET should be exactly as prescribed by your doctor. It is generally recommended to take the tablet with food, preferably at the same time each day, to improve absorption and reduce the chances of missing a dose. It may take several weeks to see improvement, and consistent use as directed is important for optimal results. The maximum recommended dose can be up to 2 mg per kilogram per day.

What are the possible side effects of GLOTRET 5 MG TABLET?

Common side effects include dry skin, chapped lips, dry eyes, nasal dryness, headache, and muscle or joint pain. Other possible side effects include increased liver enzymes, changed blood fat and cholesterol levels, easy bruising, bleeding or clotting, and a higher propensity for infections. If you experience severe reactions like mood changes, persistent headaches, or vision problems, or if common side effects persist or worsen, consult your doctor immediately.

Is GLOTRET 5 MG TABLET safe during pregnancy or breastfeeding?

No, GLOTRET 5 MG TABLET is considered highly unsafe during pregnancy. It can cause severe birth defects. Women of childbearing potential must use reliable contraceptive methods before, during, and for at least one month after stopping treatment.

It is also probably unsafe to use during breastfeeding as it is not known if the medicine passes into breast milk and could harm the baby. Breastfeeding should be discontinued while receiving treatment with this medicine.

Can GLOTRET 5 MG TABLET be taken with other medications?

You should inform your doctor about all medicines, supplements, or herbal products you are taking or plan to take. GLOTRET 5 MG TABLET interacts with certain medications. It should not be taken with Vitamin A supplements due to the risk of toxicity. Certain antibiotics like minocycline and doxycycline (tetracycline class) should also be avoided as they can increase the risk of increased pressure in the brain. Caution is advised with phenytoin (used for fits) and corticosteroids (e.g., betamethasone, prednisolone, dexamethasone) as they may cause weak bones. Hormonal contraceptives may also interact.

What precautions should be taken while using GLOTRET 5 MG TABLET?

While using GLOTRET 5 MG TABLET, it is important to:

• Avoid excessive sun exposure and use sunscreen, as the medication can increase sun sensitivity and skin fragility.
• Avoid cosmetic procedures such as waxing, dermabrasion, or laser treatments during and for at least 6 months after treatment, as the skin may become more fragile and increase the risk of scarring.
• Stay hydrated and use moisturizers and lubricating eye drops to manage dryness of the skin, lips, mouth, and eyes.
• Do not donate blood during treatment and for at least one month after stopping the medication.
• Inform your doctor if you experience mood changes, depression, or anxiety, as these are rare but potentially serious side effects.
• Avoid alcohol consumption as it can increase the risk of liver damage and worsen side effects.
• This medicine can cause decreased night vision, which can happen suddenly. Avoid driving or operating machinery at night if you experience this.
• Inform your doctor if you have a history of diabetes, obesity, liver or intestine disease, or abnormal white blood cell count.

What happens if a dose of GLOTRET 5 MG TABLET is missed?

If you miss a dose of GLOTRET 5 MG TABLET, take it as soon as you remember. However, if your next dose is approaching, skip the missed dose and continue with your regular schedule. Do not double the dose to compensate for a missed one.

How should GLOTRET 5 MG TABLET be stored?

GLOTRET 5 MG TABLET should be stored in a cool, dry place, away from direct sunlight and out of the reach of children. Ensure it is stored at temperatures between 10ºC to 25ºC or below 30ºC. Do not use the medicine past its expiry date.