Metaspan-10 Tablet

METASPAN-10 TABLET is a meticulously crafted supplement by AJANTA PHARMA LTD, designed to address various nutritional deficiencies and support overall metabolic health.

Name

• Brand Name: METASPAN-10 TABLET
• Common Name: Metaspan Tablet

Composition

Each METASPAN-10 TABLET typically contains a synergistic blend of active ingredients:

• L-Methyl Folate (3mg): A bioactive form of folate crucial for red blood cell production, DNA synthesis, and repair. It also helps manage low folate levels and may increase nitric oxide vasodilator levels to improve blood flow to peripheral nerves.
• Methylcobalamin (2mg): An active form of Vitamin B12, essential for nerve health, DNA synthesis, red blood cell production, and the metabolism of fats and carbohydrates.
• Pyridoxal-5-phosphate (35mg): The active form of Vitamin B6, vital for amino acid metabolism, neurotransmitter synthesis, maintaining hormonal balance, and supporting hemoglobin formation and blood glucose regulation.

Uses

METASPAN-10 TABLET is prescribed for a range of conditions, primarily focusing on nutritional support and metabolic health:

• Management of nutritional deficiencies, particularly deficiencies in Vitamin B6, B9 (folate), and B12.
• Support for nerve health and protection of nerve cells, especially in conditions like diabetic peripheral neuropathy, alcoholic neuropathy, and drug-induced neuropathy.
• Treatment and prevention of anemia by promoting healthy red blood cell formation.
• Management of hyperhomocysteinemia (high levels of homocysteine), which can reduce the risk of cardiovascular conditions like atherosclerosis and endothelial dysfunction.
• Aids in controlling blood sugar levels and improving insulin sensitivity.
• May assist in the management of Polycystic Ovary Syndrome (PCOS).
• Supports overall energy levels and brain health.

Dosage and Administration

METASPAN-10 TABLET should be taken exactly as prescribed by a healthcare provider.

• Typically, it is taken orally, usually once daily.
• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
• It can be taken with or without food, but maintaining consistency by taking it at the same time each day is advisable for optimal absorption.
• Do not exceed the recommended dosage or duration of treatment.
• If a dose is missed, take it as soon as remembered, unless it is almost time for the next dose. In that case, skip the missed dose and continue the regular schedule. Do not double the dose.

Side Effects

While generally well-tolerated, some individuals may experience side effects:

• Common Side Effects: Allergic reactions, acne, skin reactions, light sensitivity, nausea, vomiting, abdominal pain, loss of appetite, mild diarrhea, tingling or pricking sensation, sleepiness, and headaches.
• Serious Side Effects: Increased levels of liver enzymes, polycythemia vera (a type of blood cancer), itching, temporary skin rash accompanied by fever, and swelling of the entire body.
• If any side effects worsen or unusual symptoms occur, consult a doctor immediately.

Precautions

• Medical Conditions: Inform your doctor about any pre-existing health conditions, especially kidney disease, liver disease, heart problems, stomach ulcers, or a history of allergic reactions to vitamins or supplements.
• Drug Interactions: Disclose all other medications, supplements, and herbal products being taken to avoid potential drug interactions. Be cautious if taking blood thinners, aspirin, other NSAIDs, carbamazepine, digoxin, flucytosine, or phenytoin.
• Pregnancy and Breastfeeding: While generally considered safe, it is advisable to consult a doctor before using METASPAN-10 TABLET during pregnancy or breastfeeding. L-Methyl Folate is essential during pregnancy.
• Alcohol Consumption: It is generally advised to limit or avoid excessive alcohol consumption, as it may interfere with the medication's effectiveness or increase side effects.
• Children: The safety and efficacy of METASPAN-10 TABLET in children have not been fully established; consult a doctor for appropriate dosage in children.
• If scheduled for surgery, you may be asked to stop taking the tablet a few weeks prior.

Storage

• Store METASPAN-10 TABLET in a cool and dry place, preferably below 25°C.
• Protect from moisture and direct sunlight.
• Keep out of the reach of children and pets.

Here are frequently asked questions about METASPAN-10 TABLET, along with concise answers:

What is METASPAN-10 TABLET used for?

METASPAN-10 TABLET is primarily used to manage nutritional deficiencies, specifically those involving essential B vitamins like B6, B9 (folate), and B12. It is also prescribed to support nerve health, particularly in conditions such as diabetic peripheral neuropathy, and to manage hyperhomocysteinemia (high levels of an amino acid called homocysteine), which can be a risk factor for heart conditions. Additionally, it may be used to help prevent pregnancy-related complications like neural tube defects and anemia, and to improve overall metabolic health and energy levels.

How does METASPAN-10 TABLET work?

METASPAN-10 TABLET is a combination of L-Methylfolate, Methylcobalamin, and Pyridoxal-5-phosphate, which are active forms of Vitamin B9, B12, and B6, respectively. L-Methylfolate helps in DNA synthesis, red blood cell production, and converts homocysteine to methionine. Methylcobalamin is crucial for nerve health, red blood cell formation, and DNA synthesis. Pyridoxal-5-phosphate supports amino acid metabolism, neurotransmitter synthesis, and maintains hormonal balance. Together, these ingredients work synergistically to support cellular and metabolic functions, improve nerve function, and help in red blood cell production.

What is the usual dosage of METASPAN-10 TABLET?

METASPAN-10 TABLET should be taken orally, usually once daily, or as directed by your physician. It is crucial to adhere to the prescribed dosage and duration of treatment. The tablets should be swallowed whole with a glass of water, preferably around the same time each day to maintain consistent blood levels of the medication. It can be taken with or without food, though taking it with food may be beneficial if you experience stomach upset.

What are the possible side effects of METASPAN-10 TABLET?

Common side effects of METASPAN-10 TABLET may include nausea, vomiting, stomach pain, abdominal pain, diarrhea, constipation, loss of appetite, headaches, dizziness, and skin reactions such as acne, rash, or itching. Less common side effects can involve fatigue, weakness, drowsiness, insomnia, and allergic reactions (like hives, swelling of the face/tongue/throat, or difficulty breathing). If you experience any unusual or severe side effects, it is important to consult your doctor immediately.

Is METASPAN-10 TABLET safe during pregnancy or breastfeeding?

METASPAN-10 TABLET is generally considered safe for use during pregnancy and while breastfeeding; however, it is advised to consult your doctor before taking it. L-Methylfolate, one of the key ingredients, is particularly essential during pregnancy for preventing neural tube defects.

Can it be taken with other medications?

It is generally safe to take METASPAN-10 TABLET with other medications, but it is important to inform your doctor about all other medications, supplements, and herbal products you are currently taking. This is crucial to avoid potential drug interactions, especially if you are taking medicines for parasitic infections (e.g., pyrimethamine, pentamidine), fits (e.g., carbamazepine, phenytoin), Parkinson's disease (e.g., levodopa), bacterial infections (e.g., erythromycin), or to control blood cholesterol levels (e.g., cholestyramine, colestipol). Be particularly cautious if you are taking blood thinners, aspirin, or other NSAIDs.

What precautions should be taken?

Before starting METASPAN-10 TABLET, inform your doctor about any pre-existing medical conditions, especially kidney or liver problems, as dosage adjustments might be necessary. Avoid exceeding the recommended dosage. While there are no known interactions with alcohol, it is advisable to limit consumption. Maintain a healthy lifestyle, including a balanced diet and regular exercise, to support overall well-being.

What happens if a dose is missed?

If you miss a dose of METASPAN-10 TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should it be stored?

METASPAN-10 TABLET should be stored at room temperature, below 25°C, away from direct sunlight and moisture. Keep it out of reach of children and pets.