Cardace H 10

CARDACE H 10

CARDACE H 10 is a combination medication manufactured by Sanofi India Ltd., primarily used for the treatment of hypertension (high blood pressure). This medicine helps to control blood pressure when a single medication is not effective and also reduces the risk of future heart attacks and strokes.

Composition Each tablet of CARDACE H 10 contains:

• Ramipril: 10 mg
• Hydrochlorothiazide: 12.5 mg

Ramipril is an Angiotensin-Converting Enzyme (ACE) inhibitor that relaxes blood vessels by blocking the action of angiotensin II, a substance that tightens blood vessels. Hydrochlorothiazide is a thiazide diuretic (water pill) that increases the excretion of water and salt from the body, thereby reducing fluid overload and easing the heart's workload.

Uses CARDACE H 10 is prescribed for:

• Hypertension (high blood pressure)
• Cardiovascular risk reduction in patients who have previously suffered from heart attacks.

Dosage and Administration CARDACE H 10 can be taken with or without food, preferably in the morning to avoid frequent urination at night. It should be swallowed as a whole with water and not crushed, chewed, or broken. The dosage and duration are determined by a doctor based on the patient's medical condition. It is crucial to continue taking the medication as prescribed, even if blood pressure normalizes, and not to discontinue it without consulting a doctor.

Side Effects Common side effects include:

• Headache
• Dizziness
• Fatigue/Tiredness
• Nausea
• Cough
• Stomach pain, indigestion, diarrhea, taste change

Serious side effects, though less common, can include angioedema (swelling of the face, lips, tongue, or throat) requiring urgent medical attention.

Precautions

• Pregnancy and Breastfeeding: CARDACE H 10 is not recommended during pregnancy as it can harm the developing fetus and should be avoided by breastfeeding women.
• Alcohol: Avoid alcohol consumption as it may increase the risk of low blood pressure and dizziness.
• Medical Conditions: Caution is advised in patients with kidney disease, liver disease, diabetes, or heart problems.
• Interactions: Inform your doctor about all medications, including potassium supplements, as they can lead to high potassium levels.
• Alertness: It may cause dizziness, so avoid driving or operating heavy machinery until you know how it affects you.

Storage Store CARDACE H 10 below 25°C or at room temperature, protected from moisture and light, and out of reach of children.

Here are some frequently asked questions about Cardace H 10:

What is Cardace H 10 used for?

Cardace H 10 is primarily used to treat hypertension, also known as high blood pressure. It is a combination medication prescribed when a single medicine is not sufficient to control blood pressure. By lowering high blood pressure, it helps reduce the risk of future serious health complications such as heart attacks, strokes, and kidney problems.

How does Cardace H 10 work?

Cardace H 10 contains two active ingredients: Ramipril and Hydrochlorothiazide. Ramipril is an Angiotensin-Converting Enzyme (ACE) inhibitor that works by blocking a hormone called angiotensin, which is responsible for narrowing blood vessels. This action allows blood vessels to relax and widen, making it easier for blood to flow and lowering blood pressure. Hydrochlorothiazide is a diuretic, also known as a "water pill." It helps the kidneys remove excess water and salt from the body through increased urine output, which further reduces blood volume and pressure, easing the workload on the heart.

What is the usual dosage of Cardace H 10?

Cardace H 10 is typically taken once daily, usually in the morning, with or without food. It is important to follow your doctor's exact prescription regarding dosage and duration. This medication is generally not for initial therapy but rather for patients whose blood pressure is already controlled with individual components or not adequately controlled with Ramipril alone.

What are the possible side effects of Cardace H 10?

Common side effects can include headache, dizziness, fatigue, dry cough, nausea, indigestion, taste changes, diarrhea, and stomach pain. More serious, though less common, side effects include angioedema (swelling of the face, lips, tongue, or throat), significant drops in blood pressure (hypotension), and electrolyte imbalances (such as changes in potassium levels). If you experience any severe or persistent side effects, you should consult your doctor immediately.

Is Cardace H 10 safe during pregnancy or breastfeeding?

Cardace H 10 is generally considered unsafe to use during pregnancy as it can cause serious harm to the unborn baby. If pregnancy is detected, this medicine should be discontinued immediately. It is also not recommended for use during breastfeeding, as the medicine may pass into breast milk, and its effect on the baby is unknown.

Can Cardace H 10 be taken with other medications?

Cardace H 10 can interact with various other medications. It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential interactions. Notable interactions include:

• Other blood pressure medications: Especially those containing aliskiren (in diabetic patients or those with kidney impairment) or Angiotensin II Receptor Blockers (ARBs), due to increased risk of side effects.
• Potassium-sparing diuretics or potassium supplements: Can increase the risk of high potassium levels in the blood (hyperkalemia).
• Lithium: May increase the risk of lithium toxicity.
• NSAIDs (Nonsteroidal Anti-inflammatory Drugs): May reduce the blood pressure-lowering effect and potentially worsen kidney function.
• Alcohol: Should be avoided as it can enhance the blood pressure-lowering effect and increase side effects like dizziness and headache.

What precautions should be taken while on Cardace H 10?

Several precautions are advised while taking Cardace H 10:

• Kidney and Liver Conditions: Inform your doctor if you have any kidney or liver disease, as dose adjustments may be necessary, and the medication is contraindicated in severe cases.
• Diabetes: Cardace H 10 can affect blood sugar levels, so close monitoring is required for diabetic patients.
• Dehydration and Electrolytes: The diuretic component can cause dehydration and electrolyte imbalances. Drink plenty of fluids as advised by your doctor and report symptoms like unusual thirst, muscle weakness, or dry mouth. Regular monitoring of blood pressure, kidney function, and electrolyte levels is recommended.
• Driving and Machinery: Cardace H 10 may cause dizziness or sleepiness, especially at the start of treatment. Avoid driving or operating heavy machinery until you know how the medication affects you.
• Angioedema History: Do not take this medicine if you have a history of angioedema (severe allergic reaction with swelling) related to ACE inhibitors.

What happens if a dose of Cardace H 10 is missed?

If you miss a dose of Cardace H 10, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Cardace H 10 be stored?

Cardace H 10 tablets should be stored at room temperature and kept out of the reach of children.