Here is a detailed product description for AMLONG TRIO.

AMLONG TRIO

• Name: Amlong Trio (Brand Name), Amlong Trio Tablet (Common Name)
• Manufacturer: Micro Labs Ltd.

Composition

AMLONG TRIO is a fixed-dose combination medication containing three active ingredients:

• Telmisartan (40mg)
• Amlodipine (5mg)
• Hydrochlorothiazide (12.5mg)

Telmisartan is an angiotensin receptor blocker (ARB) that relaxes blood vessels. Amlodipine is a calcium channel blocker that widens blood vessels. Hydrochlorothiazide is a diuretic that helps the kidneys remove excess salt and water, reducing fluid retention. Together, these components work to lower blood pressure.

Uses

AMLONG TRIO is primarily prescribed for:

• Managing hypertension (high blood pressure), especially when single therapies are insufficient.
• Reducing the risk of serious cardiovascular events such as heart attack, stroke, and kidney damage.
• Managing angina (chest pain) and improving overall cardiovascular health.

Dosage and Administration

• The typical dosage is one tablet per day, but it may vary based on individual blood pressure and response to medication.
• It can be taken with or without food.
• It is recommended to take the tablet at the same time each day for consistent effectiveness.
• Swallow the tablet whole with water; do not crush or chew it.
• Due to the diuretic component (Hydrochlorothiazide), avoid taking it within four hours of bedtime to prevent excessive nighttime urination.
• Do not stop taking the medication abruptly without consulting a doctor, as sudden discontinuation can increase the risk of heart rhythm changes, blood pressure spikes, chest pain, or heart attack.

Side Effects

Common Side Effects:

• Headache
• Dizziness, lightheadedness
• Fatigue, tiredness
• Taste changes
• Diarrhea, flu-like symptoms
• Sinusitis (nasal congestion)
• Muscle weakness and cramps
• Dry mouth and increased thirst
• Swelling in the feet, ankles, or legs (edema)
• Flushing, palpitations

Serious Side Effects (Seek immediate medical attention if experienced):

• Allergic reactions (rash, itching, swelling of the face, tongue, or throat, severe dizziness, difficulty breathing).
• Severe low blood pressure (fainting, extreme dizziness, or lightheadedness).
• Electrolyte imbalances (muscle weakness, irregular heartbeat, confusion, severe dehydration).
• Chest pain, fast or irregular heartbeat.
• Visual disturbances.

Precautions

• Pregnancy: AMLONG TRIO is contraindicated during pregnancy as it may cause serious harm to the developing fetus.
• Breastfeeding: Not recommended for use while breastfeeding.
• Liver Problems: Use with caution in patients with mild liver problems; dosage adjustments may be necessary. Not recommended for severe liver disease.
• Kidney Problems: Use with caution, especially in patients with severe kidney problems or those undergoing kidney transplants; regular monitoring of kidney function is essential.
• Diabetes: May affect blood sugar control; close monitoring of glucose levels is important.
• Alcohol: Avoid or limit alcohol consumption as it can increase dizziness and interfere with the medicine's effectiveness.
• Driving/Operating Machinery: May cause dizziness or drowsiness, so caution is advised.
• Dehydration: Stay hydrated by drinking plenty of fluids, especially due to the diuretic effect of hydrochlorothiazide.
• Drug Interactions: Inform your doctor about all other medications, especially NSAIDs, CNS depressants, and antidiabetic medicines, to avoid potential interactions.
• Dietary Interactions: Avoid excessive consumption of high-potassium foods as it can lead to hyperkalemia.
• Monitoring: Regular monitoring of blood pressure, kidney function, electrolytes, and blood sugar levels is essential.

Storage

• Store AMLONG TRIO tablets at room temperature, ideally below 25°C or 30°C.
• Protect from moisture, heat, and direct light.
• Keep out of the reach and sight of children and pets.
• Do not remove the tablet from the strip until just before taking it, as these tablets are sensitive to moisture.

AMLONG TRIO by MICRO LABS LTD is a combination medication primarily used for managing hypertension (high blood pressure). It combines three active ingredients: Telmisartan, Amlodipine, and Hydrochlorothiazide, which work together to effectively lower blood pressure and reduce the risk of cardiovascular events such as heart attacks and strokes.

Here are some frequently asked questions about AMLONG TRIO:

What is AMLONG TRIO used for?

AMLONG TRIO is used to treat hypertension (high blood pressure). By lowering blood pressure, it helps to reduce the risk of serious cardiovascular complications such as heart attacks, strokes, and kidney damage. It may also be used in cases where single medications are not sufficient to control blood pressure.

How does AMLONG TRIO work?

AMLONG TRIO works through the combined action of its three active components:

• Telmisartan: An angiotensin receptor blocker (ARB) that relaxes blood vessels by blocking the action of substances that cause them to tighten, allowing blood to flow more smoothly.
• Amlodipine: A calcium channel blocker that relaxes and widens blood vessels, which improves blood flow and reduces blood pressure.
• Hydrochlorothiazide: A thiazide diuretic that helps the kidneys remove excess salt and water from the body, reducing fluid buildup and lowering blood pressure.

What is the usual dosage for AMLONG TRIO?

The usual dosage is one tablet per day, taken at the same time every day for maximum effectiveness. It can be taken with or without food. Since it contains a diuretic, it's generally advised to avoid taking it within four hours of bedtime to prevent increased urination at night and sleep disturbances. Do not crush or chew the tablet; swallow it whole with water. Always follow your doctor's prescribed dosage and do not exceed it.

What are the possible side effects of AMLONG TRIO?

Common side effects may include headache, dizziness, fatigue, taste changes, diarrhea, sinusitis (nasal congestion), flu-like symptoms, muscle weakness, dry mouth, and increased thirst. Some individuals may also experience ankle swelling, flushing, or palpitations. Most of these side effects are usually mild and resolve over time. More severe, though rare, side effects can include low blood pressure (hypotension), electrolyte imbalances (like low potassium or sodium), or kidney issues. Seek immediate medical attention if you experience severe dizziness, fainting, chest pain, irregular heartbeat, or signs of an allergic reaction such as swelling of the face, tongue, or throat.

Is AMLONG TRIO safe during pregnancy or breastfeeding?

AMLONG TRIO is generally not recommended during pregnancy, especially in the second and third trimesters, as it may harm the developing baby and is considered unsafe. If you are pregnant or planning to become pregnant, consult your doctor immediately for alternative blood pressure treatments. It is also not recommended during breastfeeding because its components can pass into breast milk and may cause harm to the nursing infant. Your doctor may suggest an alternative.

Can AMLONG TRIO be taken with other medications?

AMLONG TRIO can interact with various medications. It's crucial to inform your doctor about all medicines you are taking, including over-the-counter drugs and herbal supplements. Key interactions include:

• Other antihypertensive medications: Can enhance blood pressure-lowering effects, increasing the risk of hypotension.
• NSAIDs (Non-Steroidal Anti-Inflammatory Drugs): Can reduce the blood pressure-lowering effect and may worsen kidney function.
• Lithium: May increase the risk of lithium toxicity, requiring close monitoring.
• Potassium supplements or salt substitutes containing potassium: Can increase potassium levels in the blood (hyperkalemia) when taken with AMLONG TRIO.
• Antidiabetic medicines: May affect blood glucose levels, potentially reducing their effectiveness.
• Aliskiren: Concomitant use is generally not recommended, especially in patients with diabetes or kidney issues.
• Grapefruit juice: May increase the blood levels of amlodipine, increasing the risk of side effects like low blood pressure and dizziness.

What precautions should be taken while taking AMLONG TRIO?

Before taking AMLONG TRIO, inform your doctor if you have liver or kidney problems, diabetes, low blood pressure, severe dehydration, heart conditions (like heart failure or irregular heartbeats), or certain autoimmune conditions like lupus. Regular monitoring of blood pressure, kidney function, electrolytes, and blood sugar levels is essential. Avoid alcohol consumption as it may amplify side effects like dizziness and interfere with the medicine's effectiveness. Stay hydrated to counteract potential dehydration from the diuretic component.

What happens if a dose of AMLONG TRIO is missed?

If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Consistent adherence to the medication schedule is important for effective blood pressure management.

How should AMLONG TRIO be stored?

AMLONG TRIO should be stored at room temperature, protected from moisture and heat. Keep it in its original packaging, tightly closed, and out of the reach and sight of children and pets. Do not use the medicine after its expiration date.