Trenaxa Sr 750mg Tab

TRENAXA SR 750MG Tablet

TRENAXA SR 750MG Tablet is a medication used to manage and prevent excessive bleeding in various medical conditions.

• Name

  • Brand Name: TRENAXA SR 750MG Tablet
  • Common Name: Tranexamic Acid (as an extended-release formulation)

• Composition

  • Active Ingredient: Tranexamic Acid 750mg

• Uses TRENAXA SR 750MG Tablet is an anti-fibrinolytic that works by preventing the breakdown of blood clots, thereby controlling excessive bleeding. It is prescribed for short-term treatment of bleeding in conditions such as:

  • Heavy menstrual bleeding (menorrhagia)
  • Dysfunctional uterine bleeding
  • Nosebleeds (epistaxis)
  • Bleeding after surgery, including dental extraction, oral, prostate, or bladder surgery
  • Bleeding inside the eye (traumatic hyphaema)
  • Hereditary angioneurotic edema (HANO)
  • Bleeding inside the digestive system (e.g., inflammatory bowel disease)
  • Blood in urine not caused by kidney issues
  • Trauma
  • Endometriosis

• Dosage and Administration

  • The dose and duration are determined by a doctor based on the patient's condition.
  • The tablet should be swallowed whole with water; it should not be crushed, broken, or chewed.
  • It can be taken with or without food.
  • For heavy periods, it is typically taken on the first day of menstruation for up to 5 days.

• Side Effects

  • Common Side Effects: Musculoskeletal (bone, muscle, or joint) pain, joint pain, headache, back pain, vomiting, nausea, abdominal pain, fatigue, diarrhea, low blood pressure (hypotension), sinus disorder, anemia, allergic dermatitis, lightheadedness, tiredness, and muscle cramps.
  • Serious Side Effects (Rare): Allergic reactions, seizures, changes in vision (especially color vision), blood clots (thromboembolism, deep vein thrombosis, pulmonary embolism), sudden shortness of breath, chest pain, coughing up blood, pain or swelling in arms or legs. Seek immediate medical attention if these occur.

• Precautions

  • Not recommended for patients with a known allergy to tranexamic acid or any other ingredient.
  • Caution is advised in patients with kidney disease, and dose adjustments may be necessary.
  • Not recommended for patients with blood clotting disorders, active thromboembolic diseases, or subarachnoid hemorrhage.
  • Avoid alcohol consumption as it may cause excessive drowsiness.
  • Use with caution in pregnant and breastfeeding women, only if clearly advised by a doctor.
  • Inform your doctor if you have a history of liver disease, cardiac surgery, or if you notice blood in your urine (not related to menstruation).
  • Regular vision monitoring may be advised by your doctor.
  • Not recommended for elderly women after menopause.
  • Interactions: Inform your doctor if you are taking oral contraceptives, medicines to break down blood clots (streptokinase, reteplase, tenecteplase), tamoxifen, trans-retinoic acid, or factor IX complex concentrates.

• Storage

  • Store below 30°C in a cool and dry place, away from sunlight.
  • Keep out of sight and reach of children.

TRENAXA SR 750MG TABLET contains Tranexamic Acid and is primarily used to control or prevent abnormal and unwanted bleeding. It is manufactured by Macleods Pharmaceuticals Ltd..

What is Trenaxa SR 750mg used for?

Trenaxa SR 750mg is used to treat and reduce excessive or unwanted bleeding in various conditions. These include heavy menstrual bleeding (menorrhagia), nosebleeds (epistaxis), bleeding during or after surgical procedures (such as cervical, prostate, or bladder surgery, and dental extractions in individuals with hemophilia), bleeding inside the eye (traumatic hyphaema), and a hereditary condition called angioneurotic edema (HANO).

How does Trenaxa SR 750mg work?

This medicine contains tranexamic acid, an anti-fibrinolytic agent. It works by regulating the breakdown of blood clots in the body. It blocks the release and action of plasmin, an enzyme that is crucial for the breakdown of clots. This action stabilizes the clots, thereby helping to slow down and stop bleeding.

What is the usual dosage for Trenaxa SR 750mg?

The specific dose and duration of Trenaxa SR 750mg will be determined by your doctor based on your health condition and the type of bleeding being treated. The tablet should be swallowed whole with water and should not be crushed, broken, or chewed. It is generally recommended to take this medicine with food. For heavy periods, it is typically taken on the first day of menstruation for up to 5 days. Do not take more than six tablets in a 24-hour period.

What are the possible side effects of Trenaxa SR 750mg?

Common side effects may include nausea, vomiting, diarrhea, headache, tiredness, muscle cramps, joint pain, abdominal pain, and sinus or nasal symptoms. More serious, though less common, side effects can include impaired or blurred vision (especially color vision), allergic reactions (such as hives, rash, itching, or swelling), and formation of blood clots, which could lead to conditions like deep vein thrombosis, pulmonary embolism, or cerebral thrombosis. If you experience any severe side effects, seek immediate medical attention.

Is Trenaxa SR 750mg safe during pregnancy or breastfeeding?

Pregnancy: Trenaxa SR 750mg should be used during pregnancy only if clearly advised by a doctor, as there is limited information on its effects in human pregnancy. While some animal studies show low or no adverse effects, it is known to cross the placenta. Your doctor will assess whether the benefits outweigh the potential risks. Breastfeeding: Trenaxa SR 750mg passes into human milk in small amounts. It is generally considered safe for use during breastfeeding if prescribed by a doctor, but close monitoring of the breastfed infant is recommended.

Can Trenaxa SR 750mg be taken with other medications?

Inform your doctor about all medications you are taking, as Trenaxa SR 750mg can interact with certain drugs. It should be used with caution or avoided with blood thinners (like warfarin or heparin) as its effect may be reduced. Taking it with medications that increase blood clot formation, such as oral contraceptive pills, estrogen, or aprotinin, may increase the risk of blood clots. Also, tell your doctor if you are taking fibrinolytic agents (like streptokinase) as they may counteract the effect of Trenaxa SR 750mg.

What precautions should be taken while using Trenaxa SR 750mg?

Do not take Trenaxa SR 750mg if you are allergic to tranexamic acid or any of its ingredients. Inform your doctor if you have a history of kidney disease, blood clots, seizures, or irregular menstrual cycles. Caution is advised if you have liver disease, blood in your urine (not during menstruation), or acquired color vision disturbances. Regular eye tests may be recommended for long-term treatment. It is advisable to avoid alcohol while taking this medicine as it may worsen your condition or cause excessive drowsiness.

What happens if a dose of Trenaxa SR 750mg is missed?

If you miss a dose of Trenaxa SR 750mg, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Ensure to wait at least 6 hours before taking your next dose after a missed one.

How should Trenaxa SR 750mg be stored?

Store Trenaxa SR 750mg in a cool, dry, and dark place, protected from direct sunlight, moisture, and heat. The medicine should be kept out of the reach of children and pets. Do not flush expired or unused medication down the toilet or pour it into a drain; properly dispose of it as advised by your pharmacist.