Gliptagreat 50 Mg Tablet (15 Tab)

GLIPTAGREAT 50 MG TABLET (15 TAB) by MANKIND PHARMA LTD.

Name:

• Brand Name: Gliptagreat 50 Tablet
• Common Name: Vildagliptin (active ingredient)

Composition:

• Active Ingredients: Each tablet contains Vildagliptin 50 mg.

Uses: Gliptagreat 50 Tablet is an oral anti-diabetic medication primarily used in adults for the management of type 2 diabetes mellitus. It is prescribed to help control blood sugar levels, especially when diet and exercise alone are insufficient, or when used in combination with other anti-diabetic medicines.

• Managing Type 2 Diabetes: Helps to lower and maintain blood sugar levels.
• Improving Insulin Sensitivity: Enhances the body's response to insulin, aiding in better glucose metabolism.
• Postprandial Blood Sugar Control: Effective in managing blood sugar spikes that occur after eating.
• Prevention of Complications: Helps prevent long-term complications of diabetes such as kidney damage, eyesight loss, nerve problems, and cardiovascular issues like heart attack and stroke.

Dosage and Administration: Gliptagreat 50 Tablet should be taken orally as directed by a healthcare professional.

• Typical Guidance: Usually taken once daily in the morning, or twice daily (morning and evening).
• With or Without Food: Can be taken with or without food.
• Adult Dosage: For most adult patients with type 2 diabetes, the recommended dose is typically 50 mg twice daily, taken with meals.
• Consistency: Take the medicine at the same time each day to maximize benefits and aid remembrance.
• Pediatric Use: Not recommended for use in children and adolescents below 18 years of age.

Side Effects:

• Common Side Effects:
  • Low blood glucose levels (hypoglycemia)
  • Nasopharyngitis (common cold symptoms)
  • Headache
  • Dizziness
  • Fatigue
  • Nausea
  • Tremors
  • Constipation
  • Diarrhea
  • Rashes
• Serious Side Effects (Contact doctor immediately if experienced):
  • Signs of liver disease (e.g., loss of appetite, dark-colored urine, yellow skin and eyes, severe nausea).
  • Signs of inflammation of the pancreas (e.g., severe and persistent pain in the abdomen, nausea, vomiting).

Precautions:

• Pregnancy and Breastfeeding: Not recommended for use in pregnant or breastfeeding women. Consult a doctor if pregnant or breastfeeding.
• Liver/Kidney Conditions: Use with caution in patients with a history of liver disease, kidney disease, or severe kidney impairment.
• Heart Conditions: Caution is advised for individuals with heart failure.
• Pancreatic Issues: Inform your doctor about any pre-existing pancreatic issues or a history of pancreatitis.
• Alcohol Consumption: Avoid or limit alcohol intake as it may increase the risk of low blood sugar levels.
• Drug Interactions: Inform your doctor about all medications you are taking, including insulin, insulin secretagogues (like glimepiride), ACE inhibitors, diuretics, corticosteroids, thyroid medications, digoxin, antipsychotic medicines, and glaucoma medications, as interactions may occur.
• Driving and Operating Machinery: May cause dizziness; avoid driving or operating machinery if you feel dizzy.
• Blood Sugar Monitoring: Regular monitoring of blood sugar levels is essential.
• Hypoglycemia Management: Carry a quick source of sugar (e.g., glucose tablets, sugary candy, fruit juice) to manage symptoms of low blood sugar.

Storage:

• Store in a cool and dry place.
• Protect from sunlight, moisture, and heat.
• Keep out of sight and reach of children.
• Store below 25°C or 30°C.

What is GLIPTAGREAT 50 MG TABLET used for?

GLIPTAGREAT 50 MG TABLET is primarily used to manage type 2 diabetes mellitus in adults. It is prescribed, often alongside a healthy diet and regular exercise, when these measures alone or other medications are insufficient to control blood sugar levels. It can be used as a standalone treatment or in combination with other anti-diabetic medications.

How does GLIPTAGREAT 50 MG TABLET work?

The active ingredient in GLIPTAGREAT 50 MG TABLET is Vildagliptin, which belongs to a class of medicines called Dipeptidyl Peptidase-4 (DPP-4) inhibitors. It works by increasing the levels of "incretin" hormones in the body. These hormones are released after meals and stimulate the pancreas to produce more insulin, while also decreasing the production of glucagon from the liver, thereby helping to lower elevated blood sugar levels.

What is the usual dosage of GLIPTAGREAT 50 MG TABLET?

The dosage of GLIPTAGREAT 50 MG TABLET is determined by your doctor based on your medical condition and response to treatment. For most adult patients with type 2 diabetes, a typical dose is 50 mg, usually taken once daily in the morning. In some cases, it may be prescribed as 50 mg twice daily with meals. It is important to take the medication at the same time each day to help you remember and for optimal effectiveness.

What are the possible side effects of GLIPTAGREAT 50 MG TABLET?

Common side effects may include low blood glucose levels (hypoglycemia), tremors, headache, dizziness, fatigue, and nausea. Nasopharyngitis (an infection of the nose and throat, similar to the common cold) has also been reported. Most of these side effects are usually temporary and resolve over time. However, if any side effects persist or worsen, it is advisable to consult your doctor.

Is GLIPTAGREAT 50 MG TABLET safe during pregnancy or breastfeeding?

GLIPTAGREAT 50 MG TABLET is generally not recommended for use during pregnancy, as it is classified as a Category B pregnancy drug, and limited information is available regarding its safety. Similarly, its excretion into breast milk is unknown, and it is not recommended for breastfeeding mothers. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding before taking this medicine.

Can GLIPTAGREAT 50 MG TABLET be taken with other medications?

GLIPTAGREAT 50 MG TABLET can be taken with other medications, but caution is advised as interactions can occur. For instance, taking it with insulin or insulin secretagogues (like glimepiride or glipizide) may increase the risk of low blood sugar. ACE inhibitors (e.g., enalapril, lisinopril) might increase the risk of angioedema (swelling under the skin). Diuretics, corticosteroids, and certain thyroid medications can also interact. It is crucial to inform your doctor about all medicines, supplements, and herbal products you are currently taking to avoid potential drug interactions. Patients taking digoxin (a heart medicine) should be closely monitored.

What precautions should be taken while using GLIPTAGREAT 50 MG TABLET?

Do not use GLIPTAGREAT 50 MG TABLET if you have type 1 diabetes mellitus or diabetic ketoacidosis. Exercise caution if you have a history of liver or kidney disease, or heart failure. Alcohol consumption should be limited or avoided as it can affect blood glucose levels and increase the risk of hypoglycemia. Since this medicine may cause dizziness, be cautious when driving or operating machinery. Do not stop taking the medicine abruptly without consulting your doctor, as this could lead to increased blood sugar levels. Regularly monitor your blood sugar and be prepared to manage symptoms of hypoglycemia by carrying sugary food or fruit juice.

What happens if a dose of GLIPTAGREAT 50 MG TABLET is missed?

If you miss a dose of GLIPTAGREAT 50 MG TABLET, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should GLIPTAGREAT 50 MG TABLET be stored?

GLIPTAGREAT 50 MG TABLET should be stored in a cool and dry place, away from direct sunlight, ideally at room temperature not exceeding 30°C. Keep the medicine in a tightly closed container and out of the sight and reach of children.