Ivamac 5 Mg Tablet (10 Tab)

IVAMAC 5 MG TABLET

IVAMAC 5 MG TABLET is a cardiac medication manufactured by Macleods Pharmaceuticals Ltd., primarily used for managing certain heart conditions. It belongs to a class of medicines known as hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers or heart rate-lowering agents.

• Name:

  • Brand Name: IVAMAC 5 MG TABLET
  • Common Name: Ivabradine Tablet

• Composition:

  • Active Ingredient: Ivabradine (5 mg)

• Uses: IVAMAC 5 MG TABLET is prescribed for the treatment of:

  • Symptomatic stable angina pectoris (heart-related chest pain) in adult patients who cannot tolerate or are inadequately controlled by other heart medicines like beta-blockers, and whose heart rate is at or above 70 beats per minute.
  • Chronic heart failure in adult patients, often in combination with beta-blockers or as an alternative when beta-blockers are unsuitable, particularly when the heart rate is at or above 75 beats per minute. It works by slowing the heart rate, thereby reducing the heart's workload and improving its efficiency in pumping blood.

• Dosage and Administration:

  • The typical starting adult dosage is 5 mg twice daily, taken with food.
  • Depending on the patient's response, the dosage may be increased to a maximum of 7.5 mg twice daily.
  • The tablet should be swallowed whole with water; it should not be crushed or chewed.
  • It is essential to take the medicine regularly at a fixed time each day to maintain consistent blood levels.
  • Do not stop taking Ivamac Tablet abruptly without consulting a doctor, as it can worsen the condition.

• Side Effects: Common side effects include:

  • Luminous phenomena (temporary visual brightness or flashes).
  • Slow heart rate (bradycardia).
  • High blood pressure.
  • Headache, dizziness.
  • Blurred vision.
  • Atrial fibrillation (irregular rapid contraction of the heart) and other ECG changes.
  • Nausea, abdominal pain, diarrhea.

  Serious side effects, such as fainting and significant heart rhythm disturbances, require immediate medical attention.

• Precautions:

  • IVAMAC 5 MG TABLET is not recommended for individuals under 18 years of age.
  • It is contraindicated in patients with severe liver disease, very low resting heart rate, heart rhythm irregularities (like sick sinus syndrome, third-degree AV block, or pacemaker-controlled heart rate), very low blood pressure, or recently worsened heart failure.
  • Caution is advised in patients with mild to moderate liver or kidney problems.
  • Avoid consuming grapefruit juice while taking this medicine as it may increase its concentration in the body.
  • This medication can interact with other drugs, including certain antifungals (e.g., ketoconazole, fluconazole), HIV medications (e.g., ritonavir, nelfinavir), some antibiotics (e.g., clarithromycin, erythromycin), antidepressants (e.g., nefazodone), and certain blood pressure/heart disease medicines (e.g., diltiazem, verapamil). Always inform your doctor about all current medications and supplements.
  • IVAMAC 5 MG TABLET is highly unsafe for use during pregnancy and breastfeeding. Effective birth control measures should be used during treatment.
  • As it may cause dizziness, blurred vision, or sleepiness, avoid driving or operating heavy machinery until you understand how the medicine affects you.
  • Regular monitoring of heart rate and blood pressure is important during treatment.

• Storage:

  • Store IVAMAC 5 MG TABLET at room temperature, protected from moisture and heat.
  • Keep out of reach and sight of children and pets.
  • Generally, store below 30°C or between 10°C to 25°C.

What is IVAMAC 5 MG TABLET used for?

IVAMAC 5 MG TABLET, containing Ivabradine, is primarily used to treat symptomatic stable angina (heart-related chest pain) in adults who cannot tolerate or achieve adequate control with other heart medicines like beta-blockers and have a heart rate of 70 beats per minute or higher. It is also used for chronic heart failure in adult patients with a heart rate of 75 beats per minute or higher, either in combination with beta-blockers or when beta-blockers are not suitable.

How does IVAMAC 5 MG TABLET work?

IVAMAC 5 MG TABLET works by selectively inhibiting the "funny" (If) channel pacemaker current in the sinoatrial node of the heart. This action slows down the heart rate, which reduces the heart's workload and its oxygen demand. By allowing more time for the heart to fill with blood and pump it more efficiently, it helps to alleviate chest pain and improve symptoms of heart failure without affecting myocardial contractility or blood pressure.

What is the usual dosage for IVAMAC 5 MG TABLET?

The typical starting dosage for adults is 5 mg taken twice daily with meals to improve absorption. Your doctor may adjust the dose, potentially increasing it to a maximum of 7.5 mg twice daily, depending on your response and resting heart rate. It is important to swallow the tablet whole with water and not to break, crush, or chew it. Take it regularly at a fixed time each day as prescribed by your doctor. Do not discontinue the medication abruptly without consulting your doctor.

What are the possible side effects of IVAMAC 5 MG TABLET?

Common side effects may include temporary visual brightness or flashes (luminous phenomena), a slowed heart rate (bradycardia), headache, dizziness, blurred vision, increased blood pressure, nausea, fatigue, diarrhea, and abdominal pain. More serious side effects, such as an irregular rapid heartbeat (atrial fibrillation), significant heart rhythm disturbances, or fainting, can occur and may require immediate medical attention. Inform your doctor if any side effects persist or worsen.

Is IVAMAC 5 MG TABLET safe during pregnancy or breastfeeding?

IVAMAC 5 MG TABLET is generally not recommended and is considered unsafe or contraindicated during pregnancy and for women planning to conceive, as there is limited information on its safety in pregnant women and it may harm the unborn baby. Women of childbearing potential should use reliable contraception while taking this medicine. It is also not recommended for use in breastfeeding mothers due to limited information and potential risks to the baby. Always consult your doctor before using any medicine during pregnancy or while breastfeeding.

Can IVAMAC 5 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all medications, including herbal products, vitamins, and mineral supplements you are currently taking, as IVAMAC 5 MG TABLET can interact with several drugs.

It is generally not recommended or contraindicated to take IVAMAC 5 MG TABLET with certain medications, including:

• Antifungal medicines like ketoconazole and itraconazole.
• HIV medicines such as ritonavir and nelfinavir.
• Antibiotics like clarithromycin and erythromycin.
• Certain psychiatric medicines, including pimozide and nefazodone.
• Specific heart medications like quinidine, amiodarone, diltiazem, verapamil, and bepridil.

Caution is advised when taking IVAMAC 5 MG TABLET with diuretics (water pills) like hydrochlorothiazide or furosemide, or other drugs that slow the heart rate, as this may further reduce heart rate. Additionally, avoid consuming grapefruit juice while on this medication as it may alter its effect.

What precautions should be taken while taking IVAMAC 5 MG TABLET?

Do not drive or operate heavy machinery if you experience dizziness or visual disturbances, especially temporary brightness or flashes, which are common side effects. IVAMAC 5 MG TABLET is not recommended for individuals under 18 years of age and should be used with caution in elderly patients (over 65 or 70 years old). Inform your doctor if you have a history of heart problems such as irregular heartbeats, very low blood pressure, severe heart failure, a pacemaker, sick sinus syndrome, third-degree AV block, unstable angina, or if you have liver or kidney problems, or certain eye diseases. Your blood pressure and heart rate should be monitored regularly during treatment.

What happens if a dose of IVAMAC 5 MG TABLET is missed?

If you miss a dose of IVAMAC 5 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should IVAMAC 5 MG TABLET be stored?

IVAMAC 5 MG TABLET should be stored at room temperature, protected from moisture and heat. Keep the tablets out of the reach and sight of children and pets. The recommended storage temperature is below 30°C or between 10°C to 25°C.