Zoryl Mv 1 Mg Tablet (15 Tab)

ZORYL MV 1 MG TABLET

ZORYL MV 1 MG TABLET is an anti-diabetic medication manufactured by Intas Pharmaceuticals Ltd., primarily used for the management of Type 2 Diabetes Mellitus. It combines three active ingredients to effectively control blood sugar levels when diet, exercise, or single/dual therapy medicines are not sufficient.

• Name

  • Brand Name: ZORYL MV 1 TABLET, Zoryl MV 1 Tablet SR
  • Common Name: Glimepiride + Metformin + Voglibose (combination drug)

• Composition Each tablet typically contains:

  • Glimepiride: 1 mg
  • Metformin: 500 mg
  • Voglibose: 0.2 mg

• Uses ZORYL MV 1 TABLET is prescribed for the treatment of Type 2 Diabetes Mellitus in adults. It works by increasing insulin release from the pancreas, decreasing glucose production in the liver, and slowing down carbohydrate absorption from the intestine to prevent post-meal blood sugar spikes. This multifaceted approach helps manage blood sugar levels and can reduce the risk of long-term diabetic complications such as kidney damage, eye damage, nerve problems, and cardiovascular issues like heart attack or stroke.

• Dosage and Administration The dosage of ZORYL MV 1 TABLET is determined by a healthcare professional based on the patient's condition and response to treatment. It is generally taken orally once or twice daily, preferably with or immediately before meals to minimize gastrointestinal side effects. It is crucial to adhere strictly to the prescribed dosage and not to stop the medication abruptly without consulting a doctor.

• Side Effects Common side effects may include:

  • Hypoglycemia (low blood glucose levels), characterized by dizziness, sweating, hunger pangs, and headache.
  • Nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.
  • Changes in taste or metallic taste.
  • Headache and upper respiratory symptoms. Serious side effects can include severe hypoglycemia and lactic acidosis.

• Precautions

  • Allergies: Avoid if allergic to glimepiride, metformin, voglibose, other sulfonylureas, or sulfonamides.
  • Kidney/Liver Disease: Not recommended for patients with severe kidney or liver disease due to increased risk of lactic acidosis. Use with caution in mild to moderate liver disease.
  • Pregnancy and Breastfeeding: Generally not recommended during pregnancy or breastfeeding, as it may harm the fetus or nursing child.
  • Alcohol: Alcohol consumption should be avoided as it increases the risk of hypoglycemia and lactic acidosis.
  • Other Conditions: Not for Type 1 Diabetes Mellitus, diabetic ketoacidosis, acute conditions (dehydration, severe infection), severe trauma, or certain heart or lung problems.
  • Drug Interactions: May interact with NSAIDs (e.g., ibuprofen), cardiac glycosides (e.g., digoxin), and thyroid medications (e.g., levothyroxine). Always inform your doctor about all current medications.

• Storage Store ZORYL MV 1 TABLET in a cool and dry place, away from direct sunlight. It should be kept out of sight and reach of children. Optimal storage is below 30ºC or between 10ºC to 25ºC.

ZORYL MV 1 MG TABLET, manufactured by Intas Pharmaceuticals Ltd., is a combination medication used to manage Type 2 diabetes mellitus in adults. It contains Glimepiride, Metformin, and Voglibose, which work together to help control blood sugar levels.

Here are some frequently asked questions about ZORYL MV 1 MG TABLET:

What is ZORYL MV 1 MG TABLET used for?

ZORYL MV 1 MG TABLET is prescribed for adults with Type 2 diabetes mellitus to help control high blood sugar levels. It is typically used when diet, exercise, and other single or dual therapies are not sufficient to achieve adequate blood sugar control. Managing blood glucose levels is crucial to reduce the risk of diabetes complications such as kidney damage, eye damage, nerve problems, and loss of limbs.

How does ZORYL MV 1 MG TABLET work?

ZORYL MV 1 MG TABLET is a combination of three anti-diabetic medicines: Glimepiride, Metformin, and Voglibose, each with a distinct mechanism of action.

• Glimepiride is a sulfonylurea that stimulates the pancreas to release more insulin, which helps lower blood glucose.
• Metformin is a biguanide that reduces glucose production in the liver, delays glucose absorption from the intestines, and improves the body's sensitivity to insulin.
• Voglibose is an alpha-glucosidase inhibitor that slows down the digestion and absorption of carbohydrates from the intestines, thereby preventing sharp increases in blood sugar levels after meals.

What is the usual dosage for ZORYL MV 1 MG TABLET?

The dosage of ZORYL MV 1 MG TABLET is determined by your doctor based on your medical condition and response to treatment. It is typically taken orally once or twice daily, preferably with or immediately before meals, to minimize gastrointestinal side effects. The starting dose may be low and gradually increased by your physician over 1-2 weeks based on your blood glucose levels. Do not alter your dosage without consulting your doctor.

What are the possible side effects of ZORYL MV 1 MG TABLET?

Common side effects include hypoglycemia (low blood sugar levels), nausea, diarrhea, abdominal pain, altered taste, flatulence, headache, dizziness, vomiting, loss of appetite, and upper respiratory tract infection. Less common side effects can include blurred vision, bone fracture, and weight gain. A rare but serious side effect is lactic acidosis, which requires immediate medical attention if symptoms like extreme fatigue, weakness, or severe abdominal pain occur.

Is ZORYL MV 1 MG TABLET safe during pregnancy or breastfeeding?

ZORYL MV 1 MG TABLET is generally not recommended or is contraindicated during pregnancy due to potential harm to the developing fetus. Similarly, it is probably unsafe or not recommended for use during breastfeeding, as the medicine may pass into breast milk and affect the nursing child. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can ZORYL MV 1 MG TABLET be taken with other medications?

ZORYL MV 1 MG TABLET can interact with several other medications. It is important to inform your doctor about all medicines, supplements, or herbal products you are currently taking. Potential interactions include those with Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), cardiac glycosides (like digoxin), thyroid medications (like levothyroxine), certain antibacterials (e.g., rifampicin, ciprofloxacin), antifungals (e.g., fluconazole), other oral antidiabetics, and some anticancer drugs.

What precautions should be taken while using ZORYL MV 1 MG TABLET?

You should not take ZORYL MV 1 MG TABLET if you have Type 1 diabetes mellitus, diabetic ketoacidosis, severe kidney or liver disease, or certain acute conditions like dehydration, severe infection, or severe trauma. Caution is advised if you have heart disease, mild to moderate kidney or liver impairment, pancreatitis, or low vitamin B12 levels. Regular monitoring of blood sugar levels is essential. It is important to recognize the signs of low blood sugar and carry a fast-acting source of glucose, such as sugary food or fruit juice. Alcohol consumption should be avoided as it can increase the risk of low blood sugar and lactic acidosis. Do not stop taking this medicine abruptly without consulting your doctor.

What happens if a dose of ZORYL MV 1 MG TABLET is missed?

If you miss a dose of ZORYL MV 1 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should ZORYL MV 1 MG TABLET be stored?

ZORYL MV 1 MG TABLET should be stored below 25°C or 30°C in a cool, dry place. Protect it from excessive heat, moisture, and direct sunlight. Keep the medicine securely out of sight and reach of children. Always check the expiration date on the packaging and use the medicine before this date.