Zucator M 500 Mg Tablet (10 Tab)

ZUCATOR M 500 MG TABLET

Name

Brand Name: ZUCATOR M 500 MG TABLET Common Name: Remogliflozin Etabonate and Metformin Hydrochloride Tablets

Composition

Each film-coated tablet contains:

• Remogliflozin Etabonate: 100 mg
• Metformin Hydrochloride: 500 mg

Uses

ZUCATOR M 500 MG TABLET is a combination medication primarily used for the treatment and management of type 2 diabetes mellitus in adults. It is prescribed when diet and exercise alone do not provide adequate blood sugar control. This medicine helps control high blood glucose levels by aiding in the appropriate utilization of insulin, reducing glucose production in the liver, delaying sugar absorption from the intestines, and increasing glucose excretion through urine. It also helps reduce the risk of serious diabetes complications like kidney, eye, and nerve damage, and may lower the risk of cardiovascular death in patients with type 2 diabetes and existing cardiovascular disease.

Dosage and Administration

ZUCATOR M 500 MG TABLET should be taken in the dose and duration advised by your doctor. It can be taken with or without food, preferably at the same time each day. Swallow the tablet whole with a glass of water; do not crush, chew, or break it. If a dose is missed, take it as soon as possible, but skip it if the next dose is imminent to avoid doubling up.

Side Effects

Common side effects may include:

• Nausea, vomiting, diarrhea, abdominal pain, stomach upset
• Urinary tract infections (UTIs)
• Hypoglycemia (low blood glucose level), especially when combined with other antidiabetic drugs, alcohol consumption, or skipped meals
• Headache, dizziness
• Changes in taste, sore and red tongue
• Loss of appetite

Serious side effects requiring immediate medical attention are rare but can include severe allergic reactions (hives, swelling, difficulty breathing) or signs of liver problems (nausea, vomiting, unexplained tiredness, dark urine, yellowing of skin or eyes).

Precautions

• Kidney and Liver Conditions: Inform your doctor about any existing kidney, liver, or heart conditions. The medicine is not recommended for severe renal impairment or severe liver disease.
• Pregnancy and Breastfeeding: Consult your doctor before taking ZUCATOR M 500 MG TABLET if you are pregnant or breastfeeding, as it may be unsafe.
• Alcohol: Avoid excessive alcohol intake as it can heighten the risk of adverse effects and interfere with blood sugar-lowering effects.
• Hypoglycemia: Regular monitoring of blood sugar levels is advised. Always carry a sugary snack in case of low blood sugar symptoms.
• Other Conditions: Inform your doctor if you have heart problems, diabetic ketoacidosis, skin conditions, acute pancreatitis, low blood pressure, breathing problems, type 1 diabetes, or are scheduled for an X-ray.
• Drug Interactions: Inform your doctor about all other medications you are taking, especially other antidiabetic agents, iodine contrast medium, beta-2 agonists, corticosteroids, diuretics, and certain pain/inflammation medicines.

Storage

Store in a cool and dry place, protected from moisture, sunlight, and heat. Keep the medicine out of reach and sight of children. It should be stored at a temperature between 15ºC to 30ºC or below 30ºC.

ZUCATOR M 500 MG TABLET is a combination medication primarily used for the management of Type 2 Diabetes Mellitus. It contains two active ingredients: Remogliflozin etabonate and Metformin Hydrochloride. This medicine is intended to be used in conjunction with a balanced diet and regular exercise to improve blood sugar control in adults.

What is ZUCATOR M 500 MG TABLET used for?

ZUCATOR M 500 MG TABLET is prescribed to improve glycemic control in adults with Type 2 Diabetes Mellitus when diet, exercise, and other conventional treatments are not sufficient to adequately control blood glucose levels. By effectively managing blood sugar, it helps reduce the risk of serious diabetes complications such as kidney damage, eye damage, nerve problems, and loss of limbs.

How does ZUCATOR M 500 MG TABLET work?

This medicine combines two anti-diabetic agents: Remogliflozin etabonate and Metformin.

• Remogliflozin etabonate (a SGLT2 inhibitor) works by preventing the kidneys from reabsorbing excess sugar back into the bloodstream, leading to increased glucose excretion in the urine.
• Metformin (a biguanide) functions by reducing glucose production in the liver, delaying the absorption of sugar from the intestines, and enhancing the body's sensitivity to insulin, allowing cells to utilize more circulating blood glucose.

What is the usual dosage of ZUCATOR M 500 MG TABLET?

ZUCATOR M 500 MG TABLET should be taken in the dose and duration advised by your doctor. It is generally recommended to take the tablet whole with water, preferably with food, at the same time each day, without crushing, chewing, or breaking it. Your doctor will determine the correct dose and duration based on your age, body weight, and medical condition.

What are the possible side effects of ZUCATOR M 500 MG TABLET?

Common but usually temporary side effects may include nausea, vomiting, diarrhea, abdominal pain, stomach upset, loss of appetite, and hypoglycemia (low blood glucose level), especially when combined with other antidiabetic drugs, alcohol, or skipped meals. Other potential side effects include urinary tract infections, headache, dizziness, changes in taste, and a sore/red tongue. If these side effects persist or become bothersome, it is important to consult your doctor.

Is ZUCATOR M 500 MG TABLET safe during pregnancy or breastfeeding?

ZUCATOR M 500 MG TABLET is generally not recommended during pregnancy, and its use should only be considered if deemed necessary by a physician, with the therapeutic benefits outweighing potential risks to the fetus. For breastfeeding women, it is probably unsafe, as limited human data suggests the drug may pass into breastmilk and could harm the baby. Medical advice should be sought before using this medication if pregnant or breastfeeding.

Can ZUCATOR M 500 MG TABLET be taken with other medications?

ZUCATOR M 500 MG TABLET can interact with various medications. It is crucial to inform your doctor about all medicines, supplements, or herbals you are currently taking. Notable interactions include other antidiabetic agents (which can increase the risk of hypoglycemia), iodine contrast medium (used during X-rays), beta-2 agonists, corticosteroids, diuretics, certain pain and inflammation medications, carbonic anhydrase inhibitors, and cationic medicines like digoxin and morphine.

What precautions should be taken with ZUCATOR M 500 MG TABLET?

Before taking this medication, inform your healthcare provider about any existing kidney, liver, or heart conditions. Regular monitoring of blood sugar levels and kidney function is advised during treatment. Caution is advised against excessive alcohol intake, as it can heighten the risk of adverse effects and interfere with blood sugar control. It is also not recommended for patients with severe uncontrolled diabetes, alcoholism, severe systemic infections, diabetic ketoacidosis, or severe renal impairment.

What happens if a dose of ZUCATOR M 500 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to compensate for the missed one, as this could lead to low blood sugar levels.

How should ZUCATOR M 500 MG TABLET be stored?

ZUCATOR M 500 MG TABLET should be stored in a cool and dry place, protected from moisture, sunlight, and heat. The recommended storage temperature is between 15ºC to 30ºC. Keep the medicine out of reach and sight of children.