Pantop-it 10capsules

PANTOP-IT 10CAPSULES, manufactured by INVENTIA HEALTHCARE LIMITED, is a combination medication designed to manage various acid-related gastrointestinal conditions.

Name

• Brand Name: PANTOP-IT 10CAPSULES
• Common Name: Pantoprazole and Itopride Capsules

Composition

Each capsule contains a combination of two active ingredients:

• Pantoprazole: 40 mg (a proton pump inhibitor)
• Itopride: 150 mg (a prokinetic agent)

Uses

PANTOP-IT is prescribed for the treatment of medical conditions involving excessive stomach acid and impaired gastric motility. These include:

• Gastroesophageal Reflux Disease (GERD)
• Acidity and Hyperacidity
• Peptic Ulcers (gastric and duodenal ulcers)
• Functional Dyspepsia (indigestion)
• Zollinger-Ellison Syndrome
• Erosive Esophagitis

Dosage and Administration

Typically, PANTOP-IT is taken once daily, preferably in the morning, 30-60 minutes before a meal. The capsule should be swallowed whole with a glass of water and not crushed, broken, or chewed. The dosage and duration of treatment are determined by a healthcare professional based on the patient's condition and response.

Side Effects

• Common Side Effects: Headache, nausea, stomach pain, dizziness, diarrhea, flatulence, increased saliva production, dry mouth, vomiting, and joint pain (arthralgia).
• Serious Side Effects (Rare): Severe allergic reactions, liver problems (yellowing of skin/eyes, dark urine), severe stomach pain, osteoporosis, hypomagnesemia (low magnesium levels), vitamin B12 deficiency (with long-term use), and an increased risk of bone fractures.

Precautions

• Do not use if allergic to Pantoprazole, Itopride, other proton pump inhibitors, or any ingredients in PANTOP-IT.
• Contraindicated in patients with gastrointestinal hemorrhage, obstruction, or perforation.
• Use with caution in pregnant or breastfeeding women; consult a doctor.
• May cause dizziness or drowsiness; avoid driving or operating machinery if affected.
• Avoid alcohol consumption as it may worsen drowsiness and increase stomach acid.
• Not recommended for use in children below 16 or 18 years of age.
• Inform your doctor about any history of liver or kidney problems, osteoporosis, movement disorders, or other medical conditions and all current medications.
• Long-term therapy requires medical supervision due to potential risks like bone fractures, hypomagnesemia, and vitamin B12 deficiency.

Storage

Store in a cool and dry place, protected from direct sunlight, moisture, and heat, typically between 10ºC to 25ºC or below 30ºC. Keep out of sight and reach of children.

PANTOP-IT 10CAPSULES is a combination medicine containing Pantoprazole and Itopride, used to treat various gastrointestinal conditions.

Here are some frequently asked questions about PANTOP-IT:

What is PANTOP-IT used for?

PANTOP-IT is primarily used to treat hyperacidity, gastroesophageal reflux disease (GERD), and peptic ulcers. It also helps manage symptoms like heartburn, indigestion, bloating, nausea, and difficulty swallowing, and can be used for functional dyspepsia, diabetic gastroparesis, and gastritis.

How does PANTOP-IT work?

PANTOP-IT combines two active ingredients: Pantoprazole and Itopride. Pantoprazole is a proton pump inhibitor (PPI) that works by blocking an enzyme in the stomach lining responsible for acid production, thereby reducing excessive stomach acid. Itopride is a prokinetic agent that enhances stomach contractions, speeds up gastric emptying, and improves gastric sensitivity and tension, which helps reduce bloating, nausea, and the backward flow of stomach contents.

What is the usual dosage?

The standard adult dosage is generally one capsule, containing Pantoprazole 40 mg and Itopride 150 mg, prescribed once daily. It is usually recommended to take PANTOP-IT 30-60 minutes before a meal, preferably in the morning, to ensure optimal acid suppression and improved gut motility before food intake. Swallow the capsule whole with water; do not crush, break, or chew it.

What are the possible side effects?

Common side effects of PANTOP-IT include headache, nausea, stomach pain, dizziness, and diarrhea. Other possible side effects can include flatulence, vomiting, and dry mouth. If any of these side effects persist or worsen, it's advised to consult your doctor. Long-term use may lead to osteoporosis and hypomagnesemia (low magnesium levels), and may increase the risk of certain infections or vitamin B12 deficiency.

Is it safe during pregnancy or breastfeeding?

Regarding pregnancy, pantoprazole is not usually recommended due to limited information, and some studies suggest it may be unsafe as it could harm the fetus. Your doctor may suggest a similar medicine like omeprazole if needed. For breastfeeding, while pantoprazole passes into breast milk in tiny amounts, it is unlikely to cause side effects in the infant. However, it's still advised to consult your doctor, who will decide if the benefits outweigh the risks.

Can it be taken with other medications?

Itopride/Pantoprazole may interact with certain medications. For instance, it can affect drugs metabolized by the CYP450 enzyme system (like warfarin, diazepam, phenytoin) and those that require an acidic environment for absorption (like ketoconazole, itraconazole, digoxin, or certain antiretrovirals such as atazanavir, nelfinavir, rilpivirine). Antacids can generally be taken, but it's recommended to do so 2 hours before or after PANTOP-IT to prevent interference with absorption. Always inform your doctor about all medications, supplements, or herbal remedies you are taking.

What precautions should be taken?

Do not use PANTOP-IT if you are allergic to Pantoprazole, Itopride, or any ingredients in the medicine, or to other proton pump inhibitors. Inform your doctor if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, movement disorders, liver or kidney problems, or autoimmune conditions. Avoid consuming alcohol with PANTOP-IT as it can increase stomach acid production and potentially worsen symptoms or lead to increased drowsiness. PANTOP-IT may cause dizziness, so exercise caution when driving or operating machinery until you know how it affects you. It is generally not recommended for children as safety and effectiveness have not been established.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should it be stored?

Store PANTOP-IT in its original container, tightly closed, in a cool and dry place away from sunlight and moisture. Keep it out of the reach of children. Dispose of any unused medicine safely according to instructions on the label.