Rablet L Capsule

RABLET L CAPSULE by LUPIN LTD

Name:

• Brand Name: Rablet L Capsule, Rablet L Capsule SR/PR

Composition: Rablet L Capsule contains two active ingredients:

• Rabeprazole (20 mg): A proton pump inhibitor (PPI) that reduces stomach acid production.
• Levosulpiride (75 mg): A prokinetic agent that stimulates the release of acetylcholine, increasing gastrointestinal motility and preventing acid reflux.

Uses: Rablet L Capsule is prescribed for the treatment of various gastrointestinal conditions:

• Gastroesophageal Reflux Disease (GERD) / Acid Reflux
• Peptic and Duodenal Ulcers / Intestinal Ulcers
• Irritable Bowel Syndrome (IBS), particularly when associated with bloating and delayed gastric emptying.
• Acidity, heartburn, indigestion, and Zollinger-Ellison syndrome.

Dosage and Administration:

• Typically, one capsule is taken daily on an empty stomach, ideally at least one hour before eating, or as advised by a doctor.
• Swallow the capsule whole with water; do not chew, crush, or break it.
• The dosage and duration depend on the condition's severity and patient response.

Side Effects: Common side effects may include:

• Nausea and vomiting
• Diarrhea or constipation
• Stomach pain, flatulence
• Headache, dizziness, and drowsiness
• Dry mouth
• Less common but serious side effects can include unusual production of breast milk, breast enlargement in males, altered libido, and absence of menstrual periods.

Precautions:

• Allergy: Do not take if allergic to rabeprazole, levosulpiride, or other ingredients.
• Pregnancy and Breastfeeding: Caution is advised; consult a doctor.
• Alcohol: Avoid alcohol consumption as it can worsen symptoms and side effects.
• Medical Conditions: Inform your doctor if you have liver or kidney disease, heart disease, bone diseases (like osteoporosis), Parkinson's disease, epilepsy, mental disorders, or gastrointestinal bleeding/obstruction.
• Long-term use: May increase the risk of osteoporosis-related bone fractures and hypomagnesemia.
• Driving: May cause dizziness or drowsiness; avoid driving or operating machinery if affected.
• Children: Not generally recommended for children due to insufficient safety data.

Storage:

• Store at room temperature, ideally below 30 °C.
• Protect from direct sunlight, excessive heat, and moisture.
• Keep out of reach of children.

RABLET L CAPSULE by LUPIN LTD: Frequently Asked Questions

What is Rablet L Capsule used for?

Rablet L Capsule is primarily used to treat gastroesophageal reflux disease (GERD), also known as acid reflux, peptic ulcers (including gastric and duodenal ulcers), and irritable bowel syndrome (IBS). It may also be prescribed for functional dyspepsia, Zollinger-Ellison syndrome, and diabetic gastroparesis.

How does Rablet L Capsule work?

Rablet L Capsule is a combination medicine containing Rabeprazole and Levosulpiride. Rabeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production by blocking an enzyme system called H+/K+ ATPase in the stomach lining. Levosulpiride is a prokinetic agent that works by increasing the release of acetylcholine, a chemical messenger that enhances the movement of the stomach and intestines, thereby preventing acid reflux. It also blocks dopamine D2 receptors.

What is the usual dosage for Rablet L Capsule?

The dosage of Rablet L Capsule should be taken exactly as prescribed by your doctor. It is typically advised to take one capsule daily on an empty stomach, preferably in the morning, for optimal absorption. Do not increase or decrease your dosage without consulting your doctor.

What are the possible side effects of Rablet L Capsule?

Common side effects may include nausea, vomiting, diarrhea, stomach pain, headache, dizziness, drowsiness, flatulence, constipation, weakness, and flu-like symptoms. Less common but more serious side effects can include abnormal body movements, increased breast size, abnormal milk production (galactorrhea), absence of periods, low blood pressure, severe allergic reactions (like skin blisters or peeling), yellow skin, or dark urine, which could indicate liver problems. If you experience any severe or persistent side effects, contact your doctor immediately.

Is Rablet L Capsule safe during pregnancy or breastfeeding?

Rablet L Capsule is generally not recommended during pregnancy as its components might harm the unborn baby. It is strictly not recommended for use while breastfeeding. Always inform your doctor if you are pregnant, planning to conceive, or breastfeeding before starting this medication.

Can Rablet L Capsule be taken with other medications?

Rablet L Capsule can interact with certain other medications. It is crucial to inform your doctor about all prescription drugs, over-the-counter medicines, herbal products, and vitamin supplements you are currently taking. Notable interactions include those with ketoconazole, warfarin, cyclosporine, HIV medicines (such as atazanavir, nelfinavir, saquinavir, rilpivirine), antacids, sucralfate, cisapride, anticholinergics, levodopa, and diltiazem.

What precautions should be taken while using Rablet L Capsule?

Inform your doctor about any existing health conditions, especially liver or kidney problems, heart diseases, bone disorders (as long-term use of rabeprazole may increase osteoporosis risk), mental disorders, brain tumors, fits, or diabetes. Avoid consuming alcohol while on this medication as it can worsen drowsiness, heartburn, and acidity. Due to potential dizziness and drowsiness, avoid driving or operating heavy machinery until you understand how the medicine affects you. Long-term use may also lead to a decrease in white blood cell and platelet counts. This medicine is not recommended for children and adolescents under 18 years of age.

What happens if a dose of Rablet L Capsule is missed?

If you miss a dose of Rablet L Capsule, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Rablet L Capsule be stored?

Store Rablet L Capsule at room temperature, ideally below 30°C. Keep it in a cool, dry place and protect it from direct sunlight, excessive heat, and moisture. Always ensure the medication is kept out of the reach of children. Dispose of any expired or unused medication properly.