Esam At

ESAM AT by TORRENT PHARMACEUTICALS LTD.

Name

Brand Name: ESAM AT TABLET

Composition

ESAM AT TABLET is a combination medication. It contains two active ingredients:

• S(-)Amlodipine (typically 2.5 mg or 5 mg): A calcium channel blocker that relaxes and widens blood vessels, improving blood flow and oxygen supply to the heart.
• Atenolol (typically 25 mg or 50 mg): A beta-blocker that reduces heart rate and the force of heart contractions by blocking certain hormones like adrenaline.

Uses

ESAM AT TABLET is an antihypertensive agent used to manage various cardiovascular conditions:

• Hypertension (High Blood Pressure): It effectively controls high blood pressure, reducing the risk of cardiovascular problems like stroke and heart attack.
• Angina Pectoris (Chest Pain): It is prescribed for chest pain caused by a lack of oxygen supply to the heart, including stable angina and Prinzmetal's or variant angina.
• Prevention of Heart Attacks: It can be used to reduce the risk of heart attacks in high-risk patients.
• Management of Heart Rhythm Disorders: It may promote cardiac stability by regulating certain irregular heart rhythms.

Dosage and Administration

ESAM AT TABLET should be taken as advised by a physician.

• It can be taken with or without meals, but it is often recommended to take it at the same time each day for best results.
• Swallow the tablet whole with water; do not crush, break, or chew it.
• The doctor will determine the correct dose and duration based on the patient's age, body weight, and disease condition.
• Do not stop taking the medicine without consulting your doctor, as this may worsen the condition.

Side Effects

Common side effects of ESAM AT TABLET may include:

• Swelling of ankles or other body parts (edema)
• Headache, dizziness, sleepiness, tiredness
• Palpitations (racing heartbeat), slow heartbeat
• Flushing (redness and warmth of the skin)
• Nausea, indigestion, constipation, stomach pain, changes in bowel habits
• Muscle cramps, cold hands and feet

Serious side effects are less common, but if any side effects persist or worsen, consult a doctor.

Precautions

• Pregnancy and Breastfeeding: ESAM AT TABLET should be used with caution during pregnancy and breastfeeding, only if considered necessary by the physician, as it may be harmful to the unborn baby or pass into breast milk.
• Liver and Kidney Problems: Use with caution in patients with liver or kidney problems; dose adjustment may be necessary.
• Heart Conditions: Not recommended for patients with severe heart problems such as heart failure, severe hypotension (low blood pressure), aortic stenosis, or cardiogenic shock.
• Other Conditions: Inform your doctor if you have asthma, diabetes, an overactive thyroid gland, or low blood volume.
• Alcohol: Avoid alcohol consumption as it can increase dizziness and further lower blood pressure.
• Grapefruit Juice: Avoid grapefruit juice as it can decrease blood pressure further and cause dizziness or faintness.
• Driving/Operating Machinery: Do not drive or operate heavy machinery if you experience dizziness, drowsiness, or visual disturbances.
• Drug Interactions: Inform your doctor about all other medications, including herbal remedies, as ESAM AT can interact with various drugs.

Storage

• Store in a cool and dry place, protected from direct sunlight, moisture, and heat.
• Keep out of sight and reach of children.
• Do not use expired medicine.
• Typically stored below 30°C.

ESAM AT, manufactured by Torrent Pharmaceuticals Ltd., is a combination medication primarily used to manage high blood pressure and related heart conditions. It contains two active ingredients: Atenolol and S-Amlodipine.

What is ESAM AT used for?

ESAM AT is primarily used to treat hypertension (high blood pressure) and angina pectoris (chest pain caused by reduced blood flow to the heart). It can also help reduce the risk of heart attacks and strokes in high-risk patients and manage certain irregular heart rhythms.

How does ESAM AT work?

ESAM AT combines Atenolol, a beta-blocker, and S-Amlodipine, a calcium channel blocker. Atenolol works by reducing heart rate and making the heart pump blood more efficiently. S-Amlodipine relaxes and widens blood vessels, allowing blood to flow more easily and thereby lowering blood pressure. This dual action reduces the heart's workload and improves blood supply to the heart muscles.

What is the usual dosage of ESAM AT?

Your doctor will determine the appropriate dosage and frequency based on your medical condition. ESAM AT is typically taken once daily, and it can be taken with or without food. The tablet should be swallowed whole with water; do not crush, break, or chew it. For best results, take it at the same time each day.

What are the possible side effects of ESAM AT?

Common side effects include nausea, tiredness, stomach upset or constipation, cold hands or feet, flushing (sense of warmth), dizziness, headache, sleepiness, palpitations (pounding heart), and swelling of the ankles or feet. Most of these side effects are usually temporary and resolve over time. If any side effects persist or worsen, you should consult your doctor.

Is ESAM AT safe during pregnancy or breastfeeding?

ESAM AT is generally not recommended during pregnancy as it may pose risks to the unborn baby. It should only be used if deemed absolutely necessary by a physician, where the potential benefits outweigh the risks. For breastfeeding mothers, ESAM AT is probably unsafe as its components may pass into breast milk and potentially harm the infant. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can ESAM AT be taken with other medications?

It is crucial to inform your doctor about all prescription and non-prescription medications, as well as any vitamins or supplements you are taking. ESAM AT can interact with other medicines; for instance, other antihypertensive drugs might cause an excessive drop in blood pressure, and nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce its blood pressure-lowering effect. If you are taking antidiabetic medicines, Atenolol in ESAM AT may mask symptoms of low blood sugar, requiring dosage adjustments. Grapefruit or grapefruit juice should be avoided as it can further decrease blood pressure and increase the risk of dizziness.

What precautions should be taken while using ESAM AT?

Inform your doctor if you have any liver or kidney problems, severe high or low blood pressure, other heart conditions (such as heart failure, aortic stenosis, or abnormal heart rhythms), diabetes, asthma, an overactive thyroid gland, adrenal gland diseases, or metabolic acidosis. ESAM AT is not recommended for individuals under 18 years of age. Avoid consuming alcohol, as it can increase dizziness and lower blood pressure excessively. Do not drive or operate heavy machinery if you experience dizziness or tiredness after taking this medicine. Regular monitoring of blood pressure, kidney function, and electrolyte levels may be necessary during treatment. Do not stop taking ESAM AT abruptly, as it can worsen your condition.

What happens if a dose of ESAM AT is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one, as this can be harmful.

How should ESAM AT be stored?

ESAM AT should be stored in a cool and dry place, protected from direct sunlight and moisture. Keep it out of sight and reach of children. The recommended storage temperature is below 30°C or between 10°C to 25°C.