Silybon 70mg Tab

SILYBON 70MG TAB

Name:

• Common Name: Silybon 70mg Tablet
• Brand Name: Silybon 70mg (manufactured by Micro Labs Limited)

Composition: Each tablet contains Silymarin 70mg, which is a flavonoid isolated from the milk thistle plant (Silybum marianum). Silymarin's main component, silibinin, possesses potent antioxidative and antifibrotic properties.

Uses: Silybon 70mg Tablet is primarily used as an adjunctive therapy in the management of various liver diseases. These include:

• Chronic liver diseases and liver cirrhosis
• Acute hepatitis and chronic persistent/aggressive hepatitis
• Alcoholic fatty liver disease and toxin-induced liver damage
• Jaundice
• Gallbladder disorders and menstrual disorders It works by protecting liver cells from toxins, enhancing liver cell regeneration, and providing antioxidant support.

Dosage and Administration: The typical dosage for adults is 1 tablet (70mg) taken 1 to 2 times daily, preferably with meals. Dosage may vary based on individual health conditions and physician recommendations. It should be swallowed whole with a glass of water, not crushed or chewed. This medication often requires regular use for several months or longer to achieve the most benefit.

Side Effects: Common side effects include:

• Nausea
• Abdominal pain or upset stomach
• Diarrhea
• Rash or itching
• Bloating or fullness
• Loss of appetite
• Back pain, dizziness, and hair loss Serious, though rare, side effects may include urticaria and gastroenteritis. Allergic reactions like skin rash, red/itchy skin, difficulty breathing, and swelling of the facial area are also possible.

Precautions:

• Pregnancy and Breastfeeding: Generally not recommended for use during pregnancy or breastfeeding unless advised by a doctor due to limited safety data.
• Alcohol: Alcohol consumption is not recommended during treatment due to increased risk of side effects and exacerbated liver damage.
• Allergies: Inform your doctor if you are allergic to milk thistle or plants of the Asteraceae/Compositae family (e.g., daisies, marigolds, artichokes).
• Drug Interactions: Concomitant use with Alprazolam, Lovastatin, Diazepam, Ketoconazole, Cyclosporin A, Gemfibrozil, Losartan, Peginterferon, Ribavirin, Rifampicin, Simeprevir, and Trazodone should be avoided or monitored due to potential interactions.
• Kidney/Liver Disease: Use with caution in patients with kidney disease or hepatic encephalopathy; consult a doctor.
• Diabetes: Use cautiously as it may lower blood sugar levels.
• Children: Contraindicated in children and adolescents below 18 years of age.
• Driving: Silybon 70mg Tablet is not known to have significant effects on driving or operating machinery, but if dizziness occurs, such activities should be avoided.

Storage: Store Silybon 70mg Tablet at room temperature, ideally below 25°C or 30°C, in a cool and dry place. Protect it from moisture and direct sunlight. Keep this medication out of the reach of children.

SILYBON 70MG TAB, manufactured by MICRO LABS LIMITED, contains Silymarin, a flavonoid derived from the milk thistle plant (Silybum marianum). It is primarily used to support liver health and manage various liver conditions.

What is SILYBON 70MG TAB used for?

SILYBON 70MG TAB is primarily used for the supportive management of chronic liver diseases, including liver cirrhosis, acute and chronic hepatitis, fatty liver, and liver damage caused by toxins or drugs. It also helps in conditions like alcoholic liver disease and can protect the liver from damage during general anesthesia.

How does SILYBON 70MG TAB work?

SILYBON 70MG TAB works through several mechanisms. It acts as an antioxidant, neutralizing harmful free radicals and boosting glutathione levels to protect liver cells. It also stabilizes cell membranes, preventing toxins from entering liver cells, and exhibits anti-inflammatory effects by inhibiting inflammation-promoting pathways. Additionally, it stimulates the regeneration of liver cells by promoting rRNA synthesis.

What is the usual dosage of SILYBON 70MG TAB?

The typical dosage for adults is one 70 mg tablet, taken 1 to 2 times daily, preferably with meals. However, the exact dosage and duration of treatment should always be determined by a doctor based on the individual's age, body weight, the severity of the condition, and response to treatment. It is crucial to follow the prescribed dose and not exceed it without consulting your doctor.

What are the possible side effects of SILYBON 70MG TAB?

While generally well-tolerated, SILYBON 70MG TAB can cause some side effects. Common side effects include gastrointestinal discomfort such as bloating, nausea, diarrhea, upset stomach, abdominal pain, indigestion, and loss of appetite. Other possible side effects include headache, back pain, skin rash, itching, hair loss, and dizziness. If any side effects persist or worsen, it's important to consult your doctor.

Is SILYBON 70MG TAB safe during pregnancy or breastfeeding?

SILYBON 70MG TAB is generally not recommended for use during pregnancy or breastfeeding due to a lack of sufficient safety data. It may also pass into breast milk. Pregnant or breastfeeding individuals should consult their doctor before taking this medicine to assess the risks and benefits.

Can SILYBON 70MG TAB be taken with other medications?

SILYBON 70MG TAB can interact with certain medications. It may reduce the effectiveness of oral contraceptives and can interfere with the action of immunosuppressants like cyclosporine and sirolimus. It might also increase the effects of medicines such as diazepam, alprazolam, ketoconazole, and lovastatin. It is essential to inform your doctor about all prescription, non-prescription, and herbal medicines you are currently taking to avoid potential drug interactions.

What precautions should be taken while taking SILYBON 70MG TAB?

Precautions include using caution if you have diabetes, as silymarin may lower blood sugar levels. Individuals with allergies to milk thistle or plants from the Asteraceae/Compositae family (like daisies or marigolds) should avoid this medicine. Alcohol consumption should be avoided as it can exacerbate liver damage and affect the healing process. Caution is also advised for patients with a history of kidney problems.

What happens if a dose of SILYBON 70MG TAB is missed?

If you miss a dose of SILYBON 70MG TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should SILYBON 70MG TAB be stored?

SILYBON 70MG TAB should be stored at room temperature, ideally below 30°C, away from direct sunlight and moisture. It is important to keep the medicine out of the reach of children and pets.