Lobun Forte Capsule (10 Cap)

LOBUN FORTE CAPSULE

LOBUN FORTE CAPSULE by SANZYME LTD. is a scientifically formulated probiotic supplement designed to support gut health and aid in specific medical conditions, particularly those related to kidney function.

Composition

LOBUN FORTE contains a potent blend of beneficial probiotic bacteria and prebiotics. Each capsule provides not less than 45 billion CFU (Colony-Forming Units) of the following active ingredients:

• Streptococcus Thermophilus
• Lactobacillus Acidophilus
• Bifidobacterium Longum
• Bacillus coagulans (formerly known as Lactobacillus Sporogenes) It also includes Fructooligosaccharides (FOS) as prebiotic fibers to nourish beneficial gut bacteria.

Uses

LOBUN FORTE is primarily indicated for:

• Uremic Detoxification: It helps in neutralizing uremic toxins such as creatinine, urea, indoxyl sulfate, and p-cresol, which accumulate in the blood due to compromised kidney function.
• Delaying Progression of Chronic Kidney Disease (CKD): Specifically designed to help delay the progression of CKD from stages 3-4 to End-Stage Renal Disease (ESRD) by modulating gut microbiota and reducing nitrogenous waste.
• Supporting Gut Health: The probiotic blend helps restore and maintain a healthy balance of gut bacteria, aiding digestion, promoting nutrient absorption, and preventing the growth of harmful bacteria.
• Boosting Immune System: Lactobacillus Acidophilus and other strains contribute to a healthy immune system.
• Improving Bowel Regularity: Supports overall digestive health and can help alleviate discomforts like bloating and constipation.

Dosage and Administration

Take one capsule twice daily, or as prescribed by a nephrologist or healthcare professional. It can be taken orally with or without food, though consuming it with a meal is generally recommended for better absorption and gastrointestinal tolerance. For optimal clinical benefits, consistent usage for a minimum of 6 months is advised. If swallowing whole capsules is difficult, the contents can be mixed with soft food, as advised by a professional.

Side Effects

LOBUN FORTE is generally well-tolerated. Some individuals may experience mild and self-limiting side effects, particularly when first starting the supplement, including:

• Mild bloating
• Flatulence
• Mild gastrointestinal discomfort or changes in bowel habits Rarely, allergic reactions such as itching or rash may occur. More serious but uncommon side effects can include stomach pain, nausea, diarrhea, and fever.

Precautions

• Consult a Physician: Always consult a doctor before starting LOBUN FORTE, especially if pregnant, breastfeeding, or managing any pre-existing medical conditions.
• Immunocompromised Patients: Not recommended for individuals with compromised immune systems unless specifically advised by a healthcare provider.
• Allergies: Avoid use if there is a known allergy to any of the listed probiotic strains.
• Children and Elderly: Use with caution in children and the elderly, with clinical supervision recommended for these age groups.
• Drug Interactions: Inform your doctor about any other medications, especially antibiotics or immunosuppressants, as these may interfere with the efficacy of probiotics. If taking antibiotics, it is advisable to take LOBUN FORTE 2 to 4 hours after the antibiotic dose.
• Not a Standalone Therapy: LOBUN FORTE is a dietary supplement and should be part of a comprehensive CKD treatment plan, not a standalone therapy or a replacement for dialysis or other prescribed drugs.
• Dietary Restrictions: While LOBUN FORTE itself does not impose specific dietary restrictions, patients with CKD must adhere to their nephrologist's prescribed diet.
• Vegetarian/Vegan: Users should verify the capsule composition with the manufacturer if following a strict vegetarian or vegan diet, as capsules may contain gelatin.

Storage

Store LOBUN FORTE CAPSULE in a cool, dry place, away from direct sunlight. Keep it out of reach and sight of children and pets to prevent accidental ingestion. Refrigeration is preferred for maintaining a prolonged shelf life, although it is not mandatory unless specified on the packaging. Ensure the product remains tightly sealed in its original container to prevent moisture contamination.

LOBUN FORTE CAPSULE (10 CAP) by SANZYMELTD: Frequently Asked Questions

What is LOBUN FORTE CAPSULE used for?

LOBUN FORTE CAPSULE is a probiotic supplement primarily designed to delay the progression of Chronic Kidney Disease (CKD) from stages 3-4 to End Stage Renal Disease (ESRD) by modulating gut microbiota and reducing nitrogenous waste. It aids in uremic detoxification, helps improve Glomerular Filtration Rate (eGFR), lowers serum creatinine and BUN levels, and enhances overall kidney function. Additionally, it supports gastrointestinal health, potentially reducing symptoms like bloating, constipation, irritable bowel syndrome (IBS), antibiotic-associated diarrhea, and lactose intolerance.

How does LOBUN FORTE CAPSULE work?

This medicine contains a blend of beneficial probiotic bacteria: Streptococcus thermophilus, Lactobacillus acidophilus, Bifidobacterium longum, and Bacillus coagulans. These probiotics work by metabolizing and eliminating nitrogenous waste products, such as uremic toxins like creatinine, urea, indoxyl sulfate, and p-cresol, in the colon. This process, often referred to as "gut dialysis," reduces the burden on compromised kidneys. It also helps by reducing putrefying bacteria in the colon by lowering the pH and increasing colon permeability, which enhances the excretion of toxins.

What is the usual dosage for LOBUN FORTE CAPSULE?

The typical dosage is one capsule taken twice daily, or as directed by a nephrologist or healthcare professional. It should be swallowed whole with water, preferably after meals, to improve gastrointestinal tolerance and probiotic absorption. For measurable clinical benefits, consistent usage for a minimum of 6 months is recommended.

What are the possible side effects of LOBUN FORTE CAPSULE?

LOBUN FORTE CAPSULE is generally well-tolerated. Some individuals may experience mild side effects, particularly when first starting the supplement, such as mild bloating or abdominal discomfort, flatulence, and slight changes in bowel habits. Other reported, less common side effects include stomach pain, nausea, diarrhea, and fever. Rarely, allergic reactions like itching or rash can occur due to sensitivity to a specific probiotic strain. These effects are usually temporary; if they persist or worsen, consult your doctor.

Is LOBUN FORTE CAPSULE safe during pregnancy or breastfeeding?

It is advised to consult your doctor before taking LOBUN FORTE CAPSULE if you are pregnant or breastfeeding. While some sources suggest it is considered safe, a medical professional can determine whether it is appropriate for your specific situation.

Can LOBUN FORTE CAPSULE be taken with other medications?

LOBUN FORTE CAPSULE can generally be taken with other medications, but certain precautions are necessary. It is crucial to inform your doctor about any concurrent use of antibiotics or immunosuppressants, as these might interfere with the efficacy of probiotics. If taking phosphate binders or iron supplements, a gap of 2-3 hours between medications is recommended to avoid potential interactions. It is generally advisable to wait 24-48 hours after completing an antibiotic course before starting LOBUN FORTE CAPSULE to allow beneficial bacteria to recolonize.

What precautions should be taken while using LOBUN FORTE CAPSULE?

LOBUN FORTE CAPSULE is not recommended for immunocompromised patients unless explicitly advised by a healthcare provider. Individuals with known allergies to any of the listed probiotic strains should avoid this supplement. Use with caution in children and the elderly, and clinical supervision is recommended for these age groups. It is also important to adhere to any prescribed CKD diet alongside this supplement and not to exceed the recommended dosage without consulting a medical professional.

What happens if a dose of LOBUN FORTE CAPSULE is missed?

If you miss a dose of LOBUN FORTE CAPSULE, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one.

How should LOBUN FORTE CAPSULE be stored?

LOBUN FORTE CAPSULE should be stored in a cool, dry place, away from direct sunlight. It is important to keep it out of the reach of children and pets. While not always mandatory unless specified on the packaging, refrigeration is preferred to maintain the prolonged shelf life and viability of the microbial strains. It should not be frozen, and the product should remain tightly sealed in its original container to prevent moisture contamination.