Sitaglo 50

SITAGLO 50 by ARISTO PHARMA

SITAGLO 50 is an oral anti-diabetic medication manufactured by Aristo Pharmaceuticals Pvt Ltd. It belongs to a class of medicines known as dipeptidyl peptidase-4 (DPP-4) inhibitors, used to manage type 2 diabetes mellitus.

• Name:

  • Common Name: Sitagliptin 50 mg
  • Brand Name: SITAGLO 50

• Composition:

  • Each tablet contains Sitagliptin hydrochloride monohydrate equivalent to 50 mg of Sitagliptin.

• Uses: SITAGLO 50 is prescribed to lower blood sugar levels in adults with type 2 diabetes mellitus. It is used as an adjunct to diet and exercise to improve glycemic control. It works by increasing insulin production by the pancreas, especially after meals, and decreasing glucagon secretion, which helps regulate blood sugar spikes. Proper management of type 2 diabetes can help reduce the risk of serious complications like heart disease, stroke, kidney problems, nerve damage, and eye problems.

• Dosage and Administration: The typical dosage for Sitagliptin is 100 mg once daily. However, for SITAGLO 50, which contains 50mg, the specific prescribed dose will be determined by a physician. It can be taken once a day, with or without food, and should be taken around the same time each day. Tablets should be swallowed whole. Dosage adjustments may be necessary for patients with kidney impairment.

• Side Effects:

  • Common Side Effects: Headache, stuffy or runny nose, sore throat, diarrhea, nausea, upset stomach.
  • Serious Side Effects:
    • Pancreatitis: Severe and persistent stomach pain that may spread to the back, with or without nausea and vomiting.
    • Allergic Reactions: Rash, hives, swelling of the face, lips, tongue, and throat, difficulty breathing or swallowing, blistering or peeling skin.
    • Joint Pain: Severe and disabling joint pain.
    • Heart Failure: Shortness of breath, unusual tiredness, rapid weight gain, swelling of feet or ankles.
    • Kidney Injury: Decrease in urine output, swelling of the ankles, hands, or feet.

• Precautions: Before taking SITAGLO 50, inform your doctor if you have a history of pancreatitis, kidney problems, heart failure, gallstones, or high triglyceride levels. SITAGLO 50 is not for use in patients with type 1 diabetes or diabetic ketoacidosis. Caution is advised during pregnancy and breastfeeding; consult a doctor. Patients should inform their healthcare team about all other medications, vitamins, and herbal products they are taking, as dose adjustments or careful monitoring may be needed, especially with other diabetes medications, due to the risk of hypoglycemia.

• Storage: Store SITAGLO 50 at room temperature, typically between 20°C and 25°C (68°F and 77°F), away from excessive heat, moisture, and direct sunlight. Keep it out of reach of children.

Here are the most frequently asked questions about SITAGLO 50 by ARISTO PHARMA, along with concise and accurate answers:

What is SITAGLO 50 used for?

SITAGLO 50 is used to manage type 2 diabetes mellitus in adults. It helps control high blood sugar levels when diet and exercise alone are not sufficient, or when combined with other antidiabetic medications. It also aids in preventing serious diabetes-related complications such as kidney damage, blindness, nerve problems, and reducing the risk of heart attack and stroke.

How does SITAGLO 50 work?

SITAGLO 50 contains sitagliptin, which is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by blocking the DPP-4 enzyme, which is normally responsible for breaking down certain hormones called incretins. By inhibiting DPP-4, SITAGLO 50 increases and prolongs the action of these incretin hormones. This leads to increased insulin release from the pancreas and decreased glucose production by the liver, particularly when blood sugar levels are high, thereby helping to control both fasting and post-meal blood glucose levels.

What is the usual dosage for SITAGLO 50?

SITAGLO 50 contains 50 mg of sitagliptin. It is typically taken once a day, with or without food. The exact dosage and duration will be determined by your doctor based on your specific health condition and response to the medicine. For individuals with kidney problems, a lower dose, such as 50 mg or 25 mg once daily, may be prescribed.

What are the possible side effects of SITAGLO 50?

Common side effects of SITAGLO 50 include upper respiratory tract infections, nasopharyngitis (inflammation of the nasal passages and throat), headache, and low blood sugar (hypoglycemia), especially when used with other antidiabetic medicines. Less common side effects can include joint pain, nausea, stomach pain, diarrhea, and vomiting. Serious but rare side effects can include severe and persistent stomach pain (possibly indicating pancreatitis), severe allergic reactions (rash, hives, swelling of face/lips/tongue/throat), and kidney problems.

Is SITAGLO 50 safe during pregnancy or breastfeeding?

SITAGLO 50 is generally not recommended during pregnancy due to limited information on its effects on a developing baby. If you are pregnant or planning to become pregnant, consult your doctor, as they may suggest a safer alternative. Similarly, it is usually not recommended while breastfeeding because it is unknown how much of the medicine passes into breast milk and if it could harm the baby. Your doctor will assess the risks and benefits and recommend the best course of action.

Can SITAGLO 50 be taken with other medications?

Yes, SITAGLO 50 can interact with other medications. It may increase the risk of low blood sugar (hypoglycemia) when taken with other antidiabetic medicines like insulin and sulfonylureas. Dosage adjustments of these concomitant medications might be necessary. It may also slightly increase the plasma concentrations of cardiac glycosides like digoxin. Always inform your doctor about all other medicines, supplements, or herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while using SITAGLO 50?

Before taking SITAGLO 50, inform your doctor if you have kidney disease, a history of pancreatitis, heart problems, or high triglyceride levels. Caution is advised in patients with kidney impairment, and dose adjustments may be needed. Avoid or limit alcohol consumption as it can increase the risk of low blood sugar, especially if you are also on insulin or sulfonylurea medicines. Do not stop taking SITAGLO 50 without consulting your doctor, even if your blood sugar levels are under control.

What happens if a dose of SITAGLO 50 is missed?

If you miss a dose of SITAGLO 50, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should SITAGLO 50 be stored?

SITAGLO 50 should be stored at room temperature, ideally below 30°C, and protected from dampness and moisture. Keep it in its original blister pack and out of reach of children. Always check the expiration date before use.