Pregeb Nt Tablet (10 Tab)

PREGEB NT TABLET

PREGEB NT TABLET is a prescription medicine manufactured by Torrent Pharmaceuticals Ltd. It is a combination medication primarily used for managing neuropathic pain.

• Name

  • Brand Name: Pregeb NT Tablet
  • Common Name: Pregabalin and Nortriptyline

• Composition PREGEB NT TABLET contains two active ingredients:

  • Pregabalin (75 mg)
  • Nortriptyline (10 mg)

• Uses This medicine is indicated for the management of chronic neuropathic pain, which is pain caused by nerve damage. It is prescribed for conditions such as:

  • Diabetic peripheral neuropathy
  • Postherpetic neuralgia (nerve pain after shingles)
  • Fibromyalgia (generalized musculoskeletal pain)
  • Pain associated with spinal cord injury

• Dosage and Administration PREGEB NT TABLET should be taken orally, with or without food, as advised by your doctor. It should be swallowed whole with a glass of water and not crushed, broken, or chewed. The dosage and duration of treatment are determined by the doctor based on the patient's medical condition and response to treatment. Do not take more than the prescribed dose, and do not stop the medication abruptly, as this can lead to withdrawal symptoms.

• Side Effects Common side effects may include:

  • Dizziness, sleepiness, or drowsiness
  • Nausea, constipation, dry mouth
  • Blurred vision
  • Weight gain, increased appetite
  • Peripheral edema (swelling of lower legs and hands)
  • Headache
  • Increased sweating Serious side effects, though rare, can include skin redness with blisters or peeling, and swollen face or tongue. Suicidal thoughts and behavior have also been reported in some individuals. Consult a doctor if any side effects persist or worsen.

• Precautions

  • Pregnancy and Breastfeeding: Not recommended during pregnancy unless clearly necessary and advised by a doctor. It is also not recommended for use in breastfeeding women as it may pass into breast milk.
  • Alcohol: Avoid consuming alcohol while taking PREGEB NT TABLET, as it can increase drowsiness and sleepiness.
  • Driving and Operating Machinery: This medicine may cause dizziness, sleepiness, or blurred vision. Avoid driving or operating machinery until you know how the medicine affects you.
  • Children and Elderly: Not recommended for children below 6 years of age. Use with caution in elderly patients (65 years or above) as they may be more sensitive to side effects and at increased risk of falls.
  • Pre-existing Medical Conditions: Inform your doctor if you have or had heart problems, severe liver disease, kidney problems, bipolar syndrome, or a history of seizures/fits.
  • Drug Interactions: Inform your doctor about all other medications, supplements, or herbal products you are taking to avoid potential drug interactions, especially with MAO inhibitors (taken within the last 14 days), other antidepressants, antipsychotics, and certain cough-cold medicines containing adrenaline-like drugs.

• Storage Store PREGEB NT TABLET at room temperature, ideally between 10°C to 25°C. Keep it away from heat, direct sunlight, and moisture, and out of the reach and sight of children.

What is PREGEB NT TABLET used for?

PREGEB NT TABLET is a combination medicine primarily used to treat neuropathic pain, which is pain caused by nerve damage. This includes nerve pain associated with conditions such as diabetic peripheral neuropathy, postherpetic neuralgia (nerve pain after shingles), spinal cord injury, and fibromyalgia. It aims to reduce pain and related symptoms like mood changes, sleep problems, and tiredness.

How does PREGEB NT TABLET work?

PREGEB NT TABLET contains two active ingredients: Pregabalin and Nortriptyline. Pregabalin is an anticonvulsant that works by modulating the calcium channel activity of nerve cells in the brain, thereby reducing the transmission of pain signals. Nortriptyline is a tricyclic antidepressant that increases the levels of certain chemical messengers, specifically serotonin and noradrenaline, in the brain. This action helps to reduce the pain messages reaching the brain and can also improve mood and sleep. Together, these two components provide a synergistic effect to relieve neuropathic pain.

What is the usual dosage for PREGEB NT TABLET?

The dosage of PREGEB NT TABLET should always be taken exactly as prescribed by your doctor. It is typically taken once daily, preferably at bedtime, with or without food. It's important to take it at the same time each day to maintain a consistent level of medicine in your blood. Do not exceed the prescribed dosage without consulting your doctor.

What are the possible side effects of PREGEB NT TABLET?

Common side effects of PREGEB NT TABLET can include dizziness, sleepiness or drowsiness, nausea, blurred vision, peripheral oedema (swelling of lower legs and hands), weight gain, dry mouth, constipation, headache, and nasal congestion. Other possible side effects include aggression, insomnia, shakiness, fast heart rate, uncoordinated body movements, confusion, muscle cramps, and joint pain. Most of these side effects do not require medical attention and tend to resolve over time. However, if any side effects persist or worsen, you should consult your doctor.

Is PREGEB NT TABLET safe during pregnancy or breastfeeding?

PREGEB NT TABLET is generally not recommended for use during pregnancy or for women of childbearing age unless considered absolutely necessary and advised by a doctor, due to limited information on its safety. It is also not recommended for use by breastfeeding mothers, as it may pass into breast milk and potentially harm the baby. Always consult your doctor before taking this medicine if you are pregnant, planning a pregnancy, or breastfeeding.

Can PREGEB NT TABLET be taken with other medications?

It is crucial to inform your doctor about all prescription and non-prescription medicines, supplements, or herbal products you are currently taking or plan to take to avoid potential drug interactions. PREGEB NT TABLET should not be taken with MAO inhibitors (a type of antidepressant) within 14 days of starting or stopping them. Caution is also advised with other antidepressants, antipsychotics, sympathomimetic agents (e.g., ephedrine found in some cough-cold medicines), Linezolid, Selegiline, pain killers, steroids, blood thinners, antibiotics, muscle relaxants, and medicines for diabetes, psychiatric illnesses, fits, and sleep disorders.

What precautions should be taken while taking PREGEB NT TABLET?

Avoid consuming alcohol while taking PREGEB NT TABLET, as it can increase drowsiness and dizziness. This medication may cause dizziness, sleepiness, and blurred vision, so do not drive or operate heavy machinery until you know how it affects you. Inform your doctor if you have a history of heart problems, bipolar syndrome, severe liver or kidney disease, thyroid disorder, glaucoma, or a history of fits. Do not stop taking the medicine suddenly, as this can lead to withdrawal symptoms. It may also cause weight gain, so regular exercise and a balanced diet are recommended. Additionally, it may increase sensitivity to sunburn, so wear protective clothing and use sunscreen when outdoors. This medicine is not recommended for children below 6 years of age and should be used with caution in elderly patients.

What happens if a dose of PREGEB NT TABLET is missed?

If you miss a dose of PREGEB NT TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may increase the risk of side effects. If you are unsure, consult your doctor for guidance.

How should PREGEB NT TABLET be stored?

PREGEB NT TABLET should be stored at room temperature, typically between 20-25°C. Keep it away from heat, light, and moisture. Always ensure that the medicine is kept out of the reach and sight of children and pets.