Eplebless 25 Mg Tablet (10 Tab)

Here is a detailed product description for EPLEBLESS 25 MG TABLET (10 TAB) by MANKIND PHARMA LTD.:

EPLEBLESS 25 MG TABLET

• Name: Eplebless 25 mg Tablet (Common name: Eplerenone)

• Composition:

  • Active Ingredient: Eplerenone (25 mg)

• Uses: Eplebless 25 mg Tablet is a potassium-sparing diuretic, often referred to as a "water pill". It is primarily used for:

  • High Blood Pressure (Hypertension): It helps to lower elevated blood pressure, reducing the risk of cardiovascular events such as stroke and heart attack. It can be used alone or in combination with other antihypertensive medications.
  • Heart Failure: It is prescribed for patients with heart failure, especially following a recent heart attack, to improve heart function, reduce symptoms, and lower the risk of hospitalization and death due to heart-related complications. It helps the heart pump blood more efficiently.
  • Edema: It helps alleviate swelling caused by fluid retention in the body's tissues.

• Dosage and Administration:

  • Eplebless 25 mg Tablet can be taken with or without food.
  • It is advisable to take it at a specific time each day to maintain a consistent level of medication in the body and ensure optimal effectiveness.
  • Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
  • Follow the dosage and duration as prescribed by your doctor. Do not alter the dose or stop taking the medicine without consulting your doctor.

• Side Effects: Most side effects are temporary and generally resolve over time. Common side effects include:

  • Dizziness
  • Diarrhea
  • Nausea
  • Headache
  • Cough
  • Fatigue
  • Increased potassium level in blood (hyperkalemia)
  • Increased creatinine level in blood
  • Vomiting
  • Abdominal pain

  Serious side effects, though less common, can include angioneurotic edema (swelling of the face, tongue, or throat), severe dizziness, or fainting. Promptly inform your doctor if any side effects persist or become severe.

• Precautions:

  • Kidney and Liver Conditions: Use with caution if you have kidney or liver problems, and inform your doctor about any such history. Regular monitoring of kidney function and potassium levels through blood tests will be conducted.
  • High Potassium Levels: Do not take this medicine if you have high potassium levels in your blood (hyperkalemia), as Eplebless can worsen this condition due to its potassium-sparing effect. Avoid potassium supplements or potassium-rich foods unless advised by your doctor.
  • Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. It should be used only if clearly needed and the benefits outweigh the harms.
  • Alcohol Consumption: Limit alcohol intake, as it may amplify certain side effects like dizziness.
  • Driving and Operating Machinery: This medication may cause dizziness. Avoid driving or operating heavy machinery until you know how it affects you.
  • Drug Interactions: Inform your healthcare team about all other medications you are taking, including over-the-counter drugs, herbal supplements, and other diuretics (especially potassium-sparing diuretics), as they may interact with Eplebless 25 mg Tablet. Specific interactions include lithium, tacrolimus, cyclosporine, NSAIDs, trimethoprim, and warfarin.
  • Allergies: Do not take Eplebless 25 mg Tablet if you are allergic to eplerenone or any of its components.

• Storage:

  • Store in a cool, dry place where the temperature stays below 30°C.
  • Protect it from direct sunlight and excessive heat.
  • Do not store this medicine in damp places such as bathrooms.
  • Always keep Eplebless 25 mg Tablet out of reach of children.
  • Use it before the expiry date mentioned on the package.

Here are some frequently asked questions about EPLEBLESS 25 MG TABLET (Eplerenone):

What is EPLEBLESS 25 MG TABLET used for?

EPLEBLESS 25 MG TABLET is primarily used to treat high blood pressure (hypertension) and heart failure. It also helps to reduce swelling (edema) caused by fluid retention in the body's tissues. This medication is particularly beneficial for patients with left ventricular systolic dysfunction and congestive heart failure following a heart attack.

How does EPLEBLESS 25 MG TABLET work?

EPLEBLESS 25 MG TABLET contains Eplerenone, which is a potassium-sparing diuretic. It works by blocking the action of aldosterone, a natural hormone responsible for regulating the balance of salt and water in your body. By inhibiting aldosterone, Eplerenone helps the kidneys remove excess water and salt through urine, which in turn lowers blood pressure, reduces blood volume, and decreases the strain on the heart. It also helps relax blood vessels and maintains appropriate potassium levels in the bloodstream.

What is the usual dosage for EPLEBLESS 25 MG TABLET?

Your doctor will determine the appropriate daily dosage of EPLEBLESS 25 MG TABLET based on your specific health condition and how you respond to the medicine. It is crucial to follow your doctor's instructions precisely and not to alter your dose without consulting them.

What are the possible side effects of EPLEBLESS 25 MG TABLET?

Common side effects may include headache, dizziness, diarrhea, nausea, vomiting, abdominal pain, fatigue, and cough. EPLEBLESS 25 MG TABLET can also lead to an increase in potassium and creatinine levels in the blood. If these side effects persist or worsen, you should inform your doctor promptly.

Is EPLEBLESS 25 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: Caution is advised when taking EPLEBLESS 25 MG TABLET during pregnancy. It should only be used if clearly needed, and it is essential to consult your doctor before taking this medicine if you are pregnant or planning to become pregnant. Breastfeeding: There is limited information available regarding the use of EPLEBLESS 25 MG TABLET during breastfeeding. It is generally recommended only when clearly needed, and you should consult your doctor if you are breastfeeding.

Can EPLEBLESS 25 MG TABLET be taken with other medications?

EPLEBLESS 25 MG TABLET can interact with several other medications, potentially increasing the risk of side effects or altering its effectiveness. Some medications that may interact include antifungals (e.g., ketoconazole, itraconazole), other blood pressure medications (e.g., lisinopril, losartan), NSAIDs (e.g., ibuprofen, naproxen), ciclosporin, tacrolimus, trimethoprim, and warfarin. It is contraindicated to use with Triamterene. Always inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, you are currently taking.

What precautions should be taken while taking EPLEBLESS 25 MG TABLET?

It is important to avoid potassium supplements and limit potassium-rich foods (like bananas and broccoli) as this medicine can increase potassium levels in your blood. Your doctor will regularly monitor your kidney function and blood potassium levels. Use with caution if you have kidney problems, liver disease, or diabetes. Alcohol consumption should be limited or avoided as it can increase dizziness and further lower blood pressure. Since this medication may cause dizziness, avoid driving or operating heavy machinery until you know how it affects you. Do not stop taking EPLEBLESS 25 MG TABLET suddenly without consulting your doctor, even if you feel well, as this could worsen your condition.

What happens if a dose of EPLEBLESS 25 MG TABLET is missed?

If you miss a dose of EPLEBLESS 25 MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should EPLEBLESS 25 MG TABLET be stored?

EPLEBLESS 25 MG TABLET should be kept in a cool, dry place where the temperature stays below 30°C. Protect it from direct sunlight and excessive heat. Do not store this medicine in damp places such as bathrooms. Always keep it out of the sight and reach of children.