Dajio M 10 Mg/500 Mg Tablet (10 Tab)

DAJIO M 10 MG/500 MG TABLET (10 TAB) by MICRO LABS LIMITED

Name:

• Brand Name: DAJIO M 10 MG/500 MG TABLET

Composition: DAJIO M 10 MG/500 MG TABLET contains a combination of two active antidiabetic medicines:

• Dapagliflozin (10 mg)
• Metformin (500 mg)

Uses: DAJIO M 10 MG/500 MG TABLET is prescribed for adults with Type 2 Diabetes Mellitus to control high blood sugar levels, in conjunction with a healthy diet and regular exercise. It works by improving insulin sensitivity, decreasing glucose production in the liver, and promoting glucose excretion through urine. This medication also helps to reduce the risk of serious complications associated with diabetes, such as kidney damage, blindness, nerve problems, and heart disease. Additionally, it lowers the risk of heart failure in patients with type 2 diabetes and existing heart conditions.

Dosage and Administration: This medicine should be taken orally with or without food, typically once daily in the morning, or as directed by a healthcare professional. For optimal adherence, it is advisable to take the tablet at the same time each day. Swallow the tablet whole with a glass of water; do not crush, chew, or break it. Do not stop taking this medication without consulting your doctor, as abrupt discontinuation can lead to increased blood sugar levels and a higher risk of complications.

Side Effects:

• Common Side Effects: Nausea, vomiting, diarrhea, headache, dizziness, frequent urination, mild skin rash, itchy skin, stomach ache, loss of appetite, sore throat, nasal congestion, runny nose, genital fungal infections, urinary tract infections, flatulence, changes in taste perception, difficulty in urination, back pain, increased hematocrit levels, decreased creatinine clearance, and dyslipidemia. These side effects usually resolve over time.
• Serious Side Effects (rare): Hypoglycemia (low blood sugar), especially when used with other antidiabetic medicines or alcohol, or if meals are delayed or missed. Lactic Acidosis, a rare but serious complication of metformin accumulation, can cause symptoms such as extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, seizure, stomach/abdominal pain, muscle cramps, severe tiredness, difficulty breathing, or reduced body temperature and heartbeat. Seek immediate medical attention if these serious symptoms occur.

Precautions:

• Do not take DAJIO M if you are allergic to dapagliflozin, metformin, or any other ingredient.
• It is contraindicated in individuals with Type 1 Diabetes Mellitus, severe kidney or liver disease.
• Avoid excessive or regular alcohol consumption while on this medication, as it may increase the risk of side effects.
• Consult your doctor if you are pregnant or breastfeeding before taking this medicine.
• Inform your doctor about any pre-existing medical conditions, including heart, kidney, or liver disease; breathing problems; blood disorders; dehydration; low blood pressure; or yeast infection of the genitals.
• Maintain good genital hygiene and drink plenty of fluids to prevent genital fungal infections and dehydration, respectively.
• Regular monitoring of blood sugar levels is recommended throughout the course of treatment.
• Use with caution in patients with heart, kidney, or liver disease.
• Drug interactions may occur with diuretics, insulin, insulin secretagogues (e.g., sulphonylureas), iodinated contrast agents (used in X-rays), and cimetidine.

Storage: Store DAJIO M 10 MG/500 MG TABLET in a cool and dry place, away from direct sunlight. Keep it out of sight and reach of children. The medicine should be stored at temperatures between 10ºC and 25ºC or below 30ºC.

What is DAJIO M 10 MG/500 MG TABLET used for?

DAJIO M 10 MG/500 MG TABLET is a combination medicine used with diet and exercise to improve blood sugar control in adults with Type 2 Diabetes Mellitus. It is also prescribed to reduce the risk of hospitalization for heart failure in adults with Type 2 Diabetes who have established cardiovascular disease or multiple cardiovascular risk factors. Additionally, it helps lower the risk of worsening kidney disease, end-stage kidney disease, cardiovascular death, and hospitalization for heart failure in patients with chronic kidney disease. It is not for treating Type 1 diabetes.

How does DAJIO M 10 MG/500 MG TABLET work?

This tablet contains two active ingredients: Dapagliflozin and Metformin. Dapagliflozin works in the kidneys to block a specific protein (sodium-glucose cotransporter 2 or SGLT-2), which leads to the removal of excess glucose (sugar) from the body through urine, thereby lowering blood sugar levels. Metformin, a biguanide, reduces glucose production in the liver, decreases the absorption of sugar from the stomach, and improves the body's sensitivity to insulin, helping it use sugar more effectively.

What is the usual dosage for DAJIO M 10 MG/500 MG TABLET?

For Type 2 diabetes, the usual adult dosage often starts with a tablet containing dapagliflozin 5 mg and metformin 500 mg, taken once a day. The dose may be adjusted by your doctor based on effectiveness and tolerability, but it typically does not exceed 10 mg of dapagliflozin and 2000 mg of metformin per day. DAJIO M 10 MG/500 MG TABLET should be taken orally once daily in the morning with food. Tablets should be swallowed whole and not crushed, cut, or chewed.

What are the possible side effects of DAJIO M 10 MG/500 MG TABLET?

Common side effects may include genital fungal infections, urinary tract infections, increased urination, headache, nausea, vomiting, diarrhea, runny or stuffy nose, and sore throat. More serious side effects, though rare, can include lactic acidosis (symptoms like severe muscle pain, difficulty breathing, unusual tiredness, and stomach discomfort), diabetic ketoacidosis, dehydration, and serious urinary tract infections. Contact your doctor immediately if you experience severe or unusual symptoms.

Is DAJIO M 10 MG/500 MG TABLET safe during pregnancy or breastfeeding?

Dapagliflozin is generally not recommended during pregnancy, especially in the second and third trimesters, as animal studies showed potential kidney issues in developing offspring. Other diabetes medicines, like insulin and metformin, are considered safer during pregnancy. While metformin passes into breast milk in tiny amounts and has not been linked to side effects in breastfed babies, dapagliflozin is not usually recommended during breastfeeding due to a theoretical risk to the infant's developing kidneys. Always consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Can DAJIO M 10 MG/500 MG TABLET be taken with other medications?

Yes, but caution is advised. This medicine can interact with several other drugs. For instance, using it with diuretics (water pills) may increase the risk of dehydration and low blood pressure. When taken with insulin or insulin secretagogues (like sulfonylureas), there's an increased risk of hypoglycemia (low blood sugar), and your doctor may need to adjust the dosage of these medications. It should also be temporarily stopped before certain X-ray or CT scans using iodinated contrast agents. Always inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while using DAJIO M 10 MG/500 MG TABLET?

Several precautions are important:

• Kidney and Liver Function: This medicine should not be used in patients with severe kidney or liver disease. Your kidney function may need to be checked during treatment.
• Dehydration: Drink plenty of fluids to prevent dehydration, especially if you experience vomiting, diarrhea, or heavy sweating.
• Alcohol: Limit alcohol consumption as it can increase the risk of lactic acidosis and low blood sugar.
• Lactic Acidosis: Be aware of symptoms of lactic acidosis (e.g., severe stomach pain, difficulty breathing, muscle pain, unusual tiredness) and seek immediate medical attention if they occur.
• Vitamin B12: Long-term metformin use may lead to low vitamin B12 levels, and your doctor might recommend supplements.
• Genital and Urinary Infections: Practice good hygiene to help prevent genital fungal infections. Monitor for signs of urinary tract infections.

What happens if a dose of DAJIO M 10 MG/500 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should DAJIO M 10 MG/500 MG TABLET be stored?

Store the medicine in a closed container at room temperature, ideally between 20°C to 25°C (68°F to 77°F), away from heat, moisture, and direct light. Keep it out of reach of children and pets. Do not keep outdated medicine or medicine that is no longer needed.