Espra 40 Mg Tablet (10 Tab)

ESPRA 40 MG Tablet

Name: Espra (brand name), Esomeprazole (common name)

Composition: Each tablet contains Esomeprazole 40 mg. Esomeprazole is a proton pump inhibitor (PPI).

Uses: Espra 40 mg Tablet is prescribed to reduce excessive stomach acid production. It is primarily used to treat:

• Gastroesophageal Reflux Disease (GERD), including acid reflux and healing of erosive esophagitis.
• Peptic Ulcer Disease (stomach and duodenal ulcers), and to prevent stomach ulcers caused by NSAIDs.
• Zollinger-Ellison Syndrome, a rare condition involving tumors that cause high stomach acid levels.
• It may also be used in combination therapy to eradicate Helicobacter pylori infection.

Dosage and Administration: Espra 40 mg Tablet is typically taken orally, once daily, preferably on an empty stomach at least one hour before a meal. The tablet should be swallowed whole with water and not crushed or chewed. The duration of treatment depends on the condition being treated and should be as prescribed by a doctor.

Side Effects: Common side effects may include headache, nausea, abdominal pain, diarrhea, constipation, and dry mouth. More serious or long-term side effects can include dizziness, vomiting, joint pain, skin rash, and an increased risk of bone fractures with prolonged use. Long-term use can also lead to low magnesium levels (hypomagnesaemia) and Vitamin B12 deficiency.

Precautions:

• Do not use if allergic to Esomeprazole or other proton pump inhibitors.
• Inform your doctor if you have severe liver problems, gastric cancer, low magnesium levels, low vitamin B12 levels, or osteoporosis.
• Caution is advised during pregnancy and breastfeeding, and it is generally not recommended unless clearly necessary.
• Espra 40 mg Tablet can interact with medications like blood thinners (e.g., Warfarin), antifungal drugs (e.g., Ketoconazole), anti-HIV medication, iron supplements, and anti-cancer drugs.
• Avoid driving or operating machinery if the medicine causes dizziness, drowsiness, or affects vision.
• Alcohol consumption can increase stomach acid production and should be used with caution.

Storage: Store Espra 40 mg Tablets in a cool, dry place, away from direct sunlight and moisture, preferably at room temperature (around 25°C or below 30°C). Keep out of reach of children.

ESPRA 40 MG TABLET contains Esomeprazole, a proton pump inhibitor (PPI) used to reduce stomach acid production. It is manufactured by Zydus Healthcare Limited. Here are some frequently asked questions about this medicine:

What is ESPRA 40 MG TABLET used for?

ESPRA 40 MG TABLET is primarily used to treat conditions caused by excessive stomach acid. These include Gastroesophageal Reflux Disease (GERD), stomach ulcers, peptic ulcer disease, healing of erosive esophagitis, and Zollinger-Ellison syndrome (a condition with overproduction of acid due to a pancreatic tumor). It can also be used in conjunction with antibiotics to treat stomach infections caused by H. Pylori bacteria.

How does ESPRA 40 MG TABLET work?

The active ingredient, Esomeprazole, is a proton pump inhibitor (PPI). It works by blocking the action of an enzyme system called H+/K+ ATPase, or the gastric proton pump, which is responsible for secreting acid in the stomach. By inhibiting this pump, Esomeprazole effectively reduces the amount of stomach acid produced, thereby alleviating symptoms and promoting healing.

What is the usual dosage for ESPRA 40 MG TABLET?

The usual adult dosage is typically 20 mg to 40 mg, taken once daily. It is generally recommended to take the tablet on an empty stomach, at least one hour before a meal, preferably in the morning. The tablet should be swallowed whole with water and not be crushed, chewed, or opened.

What are the possible side effects of ESPRA 40 MG TABLET?

Common side effects include headache, diarrhea, nausea, abdominal pain, vomiting, constipation, and dry mouth. If these side effects persist or worsen, it's important to consult a healthcare professional. Long-term use may lead to more serious side effects such as low magnesium levels, vitamin B12 deficiency, and an increased risk of bone fractures.

Is ESPRA 40 MG TABLET safe during pregnancy or breastfeeding?

ESPRA 40 MG TABLET is generally not recommended during pregnancy, and caution is advised. While some sources suggest it may be safe, it's important to consult your doctor who will weigh the benefits and potential risks before prescribing it. Similarly, during breastfeeding, it should be used with caution as it may pass into breast milk; discussion with a doctor is necessary.

Can ESPRA 40 MG TABLET be taken with other medications?

ESPRA 40 MG TABLET can interact with several other medications. It may decrease the effectiveness of clopidogrel and anti-HIV drugs like atazanavir and nelfinavir. It can also increase the risk of bleeding with blood thinners like warfarin. Other interactions include diazepam, digoxin, methotrexate, certain antifungal agents (e.g., ketoconazole), iron supplements, and rifampin. Always inform your doctor about all medications you are currently taking.

What precautions should be taken while using ESPRA 40 MG TABLET?

Patients with severe liver or kidney impairment, or those at risk of osteoporosis-related fractures, should use this medication with caution. Prolonged use may lead to deficiencies in Vitamin B12 and magnesium. ESPRA 40 MG TABLET can also mask the symptoms of gastric cancer, so any severe stomach pain or blood in stool should be immediately reported to a doctor. It's advisable to avoid alcohol as it can increase stomach acid production. The medication may cause dizziness or drowsiness, so operating machinery or driving should be avoided if affected.

What happens if a dose of ESPRA 40 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should ESPRA 40 MG TABLET be stored?

ESPRA 40 MG TABLET should be kept in a cool, dry place, away from direct heat, light, and moisture. It is best stored at room temperature, approximately 25°C (77°F). Ensure the medication is kept out of the reach of children.