Pentanerv Nt 100 Mg Tablet (15 Tab)

PENTANERV NT 100 MG TABLET

PENTANERV NT 100 MG TABLET is a combination medication manufactured by Alkem Laboratories Ltd., primarily prescribed for the management of neuropathic pain.

• Name: Pentanerv NT 100mg Tablet (Brand Name)

• Composition: Each tablet contains Gabapentin 100 mg and Nortriptyline 10 mg. Gabapentin is an anti-convulsant that helps relieve nerve pain by modulating calcium channel activity in nerve cells, while Nortriptyline is a tricyclic antidepressant that increases levels of serotonin and noradrenaline to prevent pain signals from moving in the brain.

• Uses: This medicine is used to treat neuropathic pain, which is pain caused by nerve damage due to conditions such as diabetes, shingles (postherpetic neuralgia), spinal cord injury, or chronic progressive nerve disease. It may also be used in the management of fibromyalgia and as an adjunctive therapy for depression, helping to improve mood and sleep patterns associated with nerve pain.

• Dosage and Administration: PENTANERV NT 100 MG TABLET should be taken orally as directed by a healthcare professional. It can be taken with or without food, but it is recommended to take it at a fixed time each day, preferably in the evening or at night, for optimal results. The tablet should be swallowed whole with water and not cut, broken, or chewed. Do not stop taking this medicine suddenly, as it may lead to withdrawal symptoms; the dose should be gradually tapered under medical supervision.

• Side Effects: Common side effects may include dizziness, drowsiness, fatigue, headache, nausea, vomiting, blurred vision, dry mouth, tingling sensations, constipation, difficulty in urination, and weight gain. More serious but uncommon side effects can include changes in body temperature, difficulty breathing, increased heart rate (palpitations), unsteadiness, mood or behavior changes (including suicidal thoughts), hallucinations, and signs of frequent infections.

• Precautions: PENTANERV NT 100 MG TABLET may cause drowsiness and dizziness; therefore, caution should be exercised when driving or operating machinery until you know how the medicine affects you. Alcohol consumption should be avoided as it can increase dizziness and drowsiness. Inform your doctor if you have a history of heart problems (it is not recommended for patients with a recent heart attack, heartbeat disorder, heart block, or coronary artery disease), kidney disease, or liver disease, as dose adjustments may be necessary. Pregnant or breastfeeding women should consult their doctor before use, as the medicine may be unsafe during pregnancy and breastfeeding. The medication is not recommended for children and adolescents under 18 years of age. If taking antacids containing aluminum or magnesium, a gap of at least two hours should be maintained between the intake of Pentanerv NT and these antacids.

• Storage: Store PENTANERV NT 100 MG TABLET at a temperature below 30°C, in a cool and dry place, away from direct sunlight, and out of the sight and reach of children.

PENTANERV NT 100 MG TABLET is a combination medicine primarily prescribed for the management of neuropathic pain. It combines Gabapentin and Nortriptyline to alleviate pain caused by nerve damage.

What is PENTANERV NT 100 MG TABLET used for?

PENTANERV NT 100 MG TABLET is primarily used to treat neuropathic pain in adults, which is a type of pain resulting from damage or dysfunction of nerves. This can occur due to various conditions such as diabetes (diabetic neuropathy), shingles (postherpetic neuralgia), or spinal cord injury. It may also be used to manage fibromyalgia and as an adjunctive therapy for depression. The medication helps reduce pain and associated symptoms like mood changes, sleep disturbances, and fatigue.

How does PENTANERV NT 100 MG TABLET work?

PENTANERV NT 100 MG TABLET contains two active ingredients: Gabapentin and Nortriptyline. Gabapentin works by modulating the activity of calcium channels in nerve cells, which helps in reducing nerve pain and can lower the risk of seizures. Nortriptyline, a tricyclic antidepressant, increases the levels of certain chemical messengers in the brain, such as serotonin and noradrenaline. By preventing the reabsorption of these messengers, Nortriptyline disrupts the movement of pain signals in the brain, providing further pain relief and improving mood.

What is the usual dosage for PENTANERV NT 100 MG TABLET?

The dosage of PENTANERV NT 100 MG TABLET should be strictly followed as directed by your doctor. The tablet is typically taken orally, whole (without chewing, crushing, or breaking), with or without food, preferably in the evening or at night. It is recommended to take it at a consistent time each day to maintain a steady level of the medication in the bloodstream. Do not take more than the prescribed dose.

What are the possible side effects of PENTANERV NT 100 MG TABLET?

Common side effects may include dizziness, drowsiness, fatigue, headache, nausea, vomiting, blurred vision, dry mouth, constipation, difficulty in urination, and weight gain. Other possible side effects include increased heart rate, uncoordinated body movements, peripheral edema, weakness, impotence, indigestion, insomnia, and mood changes. It is important to report any unusual changes in mood, including suicidal thoughts, to your doctor immediately. Most common side effects are usually mild and may resolve over time, but if they persist or worsen, consult your doctor.

Is PENTANERV NT 100 MG TABLET safe during pregnancy or breastfeeding?

PENTANERV NT 100 MG TABLET is generally not recommended during pregnancy unless deemed essential by your doctor, as animal studies have shown potential harm to the developing baby. If taken in the last weeks of pregnancy, the newborn should be monitored for withdrawal symptoms. For breastfeeding mothers, PENTANERV NT 100 MG TABLET is generally considered unsafe as it can pass into breast milk in small quantities. Your doctor will assess the benefits and risks before prescribing it during breastfeeding, and close monitoring of the baby for any undesired side effects may be advised.

Can PENTANERV NT 100 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all other medications you are currently taking, including over-the-counter drugs, supplements, and herbal remedies, as they may interact with PENTANERV NT 100 MG TABLET. Avoid taking antacids containing aluminum or magnesium within 2 hours before or after taking Pentanerv-NT 100 MG TABLET, as they can interfere with its absorption. Concomitant use with monoamine oxidase inhibitors (MAOIs) is not recommended. Caution is advised with medicines for opioid dependence, certain cough and cold medicines, some anesthetics, and high blood pressure medications.

What precautions should be taken while taking PENTANERV NT 100 MG TABLET?

PENTANERV NT 100 MG TABLET can cause dizziness and drowsiness, so it is advisable to avoid driving or operating heavy machinery until you understand how the medicine affects you. Alcohol consumption should be avoided as it can worsen these side effects. Do not stop taking this medicine abruptly, even if your symptoms improve, as sudden discontinuation can lead to withdrawal symptoms such as anxiety, sleeping difficulties, nausea, and sweating. A gradual reduction in dosage under medical supervision is usually recommended. Inform your doctor if you have a history of heart problems, kidney or liver disease, bipolar syndrome, diabetes, glaucoma, thyroid problems, or a tendency for suicidal thoughts. Regular monitoring of blood sugar levels is advised for diabetic patients. Additionally, this medication may cause weight gain, so maintaining regular physical activity and a balanced diet is recommended.

What happens if a dose of PENTANERV NT 100 MG TABLET is missed?

If you miss a dose of PENTANERV NT 100 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.

How should PENTANERV NT 100 MG TABLET be stored?

PENTANERV NT 100 MG TABLET should be stored in a cool and dry place, away from direct sunlight and moisture. Keep the medicine out of sight and reach of children. It is generally recommended to store it at room temperature, typically between 10ºC to 25ºC or below 30ºC.