Oxramet S Xr 500 Mg Tablet ( 7 Tab )

OXRAMET S XR 500 MG TABLET

Name:

• Brand Name: OXRAMET S XR 500 MG TABLET
• Common Name: Dapagliflozin, Metformin, and Sitagliptin extended-release tablets

Composition: Each extended-release tablet contains:

• Dapagliflozin: 10 mg
• Metformin: 500 mg
• Sitagliptin: 100 mg

Uses: OXRAMET S XR 500 MG TABLET is prescribed for the management of Type 2 Diabetes Mellitus in adults, used as an adjunct to diet and exercise. It works to improve blood sugar control by:

• Removing excess sugar from the body through urine (Dapagliflozin).
• Increasing natural substances that lower blood sugar and enhancing insulin release (Sitagliptin).
• Reducing sugar production by the liver and delaying sugar absorption from the intestines (Metformin). It may also offer cardiovascular and kidney protection.

Dosage and Administration: Take OXRAMET S XR 500 MG TABLET as advised by your doctor. It can be taken with or without food, but taking it with meals may help reduce stomach upset. Swallow the tablet whole; do not crush, chew, or break it, as this can affect its extended-release mechanism. Consistent daily timing is recommended for optimal benefits.

Side Effects: Common side effects may include:

• Urinary tract infections
• Nasal congestion, sore throat, upper respiratory tract infections
• Headache
• Nausea, vomiting, abdominal pain, diarrhea, flatulence, stomach upset
• Genital fungal infections
• Hypoglycemia (low blood sugar), especially when used with other antidiabetic medicines

Serious side effects are rare but require prompt medical attention and may include lactic acidosis, ketoacidosis, or severe allergic reactions.

Precautions:

• Allergies: Do not take if allergic to Dapagliflozin, Metformin, Sitagliptin, or any other component of the tablet.
• Medical Conditions: Inform your doctor about any history of kidney or liver issues, heart failure, respiratory failure, or urinary tract infections. Not recommended for Type 1 diabetes, severe kidney or liver disease, or acute metabolic acidosis.
• Pregnancy and Breastfeeding: Not recommended for use during pregnancy or breastfeeding; consult your doctor.
• Alcohol: Limit alcohol consumption, as it may increase the risk of lactic acidosis.
• Hydration: Drink plenty of fluids to prevent dehydration.
• Drug Interactions: Inform your doctor about all other medications, including herbal supplements, as interactions can occur with insulin, sulfonylureas, diuretics, certain antifungals, antivirals, and corticosteroids.
• Pediatric Use: Not recommended for children below 18 years of age.

Storage: Store in a cool, dry place, away from direct heat and sunlight, typically below 30ºC. Keep out of the sight and reach of children and pets.

Here are some frequently asked questions about OXRAMET S XR 500 MG TABLET:

What is OXRAMET S XR 500 MG TABLET used for?

OXRAMET S XR 500 MG TABLET is primarily used to manage type 2 diabetes mellitus in adults. It is prescribed when blood sugar levels are not adequately controlled by metformin alone, and is used in conjunction with diet and exercise to improve blood sugar control. It may also help reduce the risk of cardiovascular events and diabetic kidney disease in some patients.

How does OXRAMET S XR 500 MG TABLET work?

This medicine is a combination of three active ingredients: Dapagliflozin, Sitagliptin, and Metformin.

• Dapagliflozin works by increasing the excretion of glucose from the body through urine, thus lowering blood glucose levels.
• Sitagliptin helps control blood sugar by increasing the release of insulin and signaling the liver to reduce sugar production when blood sugar levels are high.
• Metformin reduces glucose production in the liver, delays glucose absorption from the intestines, and improves the body's sensitivity to insulin.

What is the usual dosage for OXRAMET S XR 500 MG TABLET?

OXRAMET S XR 500 MG TABLET should be taken exactly as directed by your doctor. It is typically taken once daily and should be swallowed whole with a glass of water, without cutting, breaking, or chewing. Taking it with food may help minimize gastrointestinal side effects. It's recommended to take it at the same time each day for optimal benefits.

What are the possible side effects of OXRAMET S XR 500 MG TABLET?

Common side effects can include urinary tract infections, nasal congestion, sore throat, upper respiratory tract infections, headache, nausea, vomiting, diarrhea, abdominal pain, flatulence, and genital fungal infections. Some individuals may also experience low blood sugar (hypoglycemia), especially if taken with other antidiabetic medicines or if meals are skipped.

Serious but rare side effects requiring immediate medical attention include signs of lactic acidosis (weakness, difficulty breathing, stomach pain), ketoacidosis (nausea, vomiting, confusion), pancreatitis (severe stomach pain), or severe allergic reactions (rash, swelling).

Is OXRAMET S XR 500 MG TABLET safe during pregnancy or breastfeeding?

OXRAMET S XR 500 MG TABLET is generally not recommended during pregnancy due to limited information on its effects on pregnant women and potential risks. It is also not recommended during breastfeeding as it is unknown if the medicine passes into human breast milk. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can OXRAMET S XR 500 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all other medicines, herbal products, or supplements you are currently taking or plan to take to avoid potential interactions. Particular care should be taken if you are also taking diuretics (water pills), other antidiabetic medicines (like insulin or sulfonylureas), medicines for fungal infections (e.g., ketoconazole), bacterial infections (e.g., clarithromycin), HIV/AIDS (e.g., ritonavir), heart failure (e.g., digoxin), carbonic anhydrase inhibitors, or certain medicines that can reduce metformin clearance.

What precautions should be taken while using OXRAMET S XR 500 MG TABLET?

This medicine is not suitable for individuals with type 1 diabetes, diabetic ketoacidosis, severe kidney or liver disease, heart failure, or severe infections. Inform your doctor if you have kidney or liver issues, a urinary tract infection, or are taking diuretics. Regular monitoring of blood sugar levels and kidney function is essential during treatment. Avoid excessive alcohol consumption as it can increase the risk of side effects like lactic acidosis. Do not stop taking the medication abruptly, as this can lead to increased blood sugar levels.

What happens if a dose of OXRAMET S XR 500 MG TABLET is missed?

If you miss a dose of OXRAMET S XR 500 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should OXRAMET S XR 500 MG TABLET be stored?

Store OXRAMET S XR 500 MG TABLET in a cool and dry place below 30°C, away from direct sunlight. Keep it out of reach of children and pets.