Tendia P Tablet (15 Tab)

TENDIA P TABLET

TENDIA P TABLET, manufactured by Eris Lifesciences Limited, is a combination medication prescribed for the management of type 2 diabetes mellitus in adults.

Composition Each tablet contains:

• Teneligliptin (20 mg)
• Pioglitazone (15 mg)

Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that enhances insulin release from the pancreas and reduces glucagon secretion. Pioglitazone is a thiazolidinedione that improves the body's sensitivity to insulin, allowing cells to utilize glucose more effectively. This dual mechanism helps to effectively lower blood sugar levels.

Uses TENDIA P TABLET is used to:

• Treat type 2 diabetes mellitus when diet and exercise alone are insufficient.
• Lower high blood sugar levels.
• Improve insulin sensitivity.
• Manage insulin resistance, which may be associated with conditions like polycystic ovary syndrome (PCOS).

Dosage and Administration Typically, TENDIA P TABLET is taken orally once daily, with or without food, or as directed by a healthcare professional. The tablet should be swallowed whole with water and not chewed, crushed, or broken. For optimal results, it is recommended to take the medication at the same time each day.

Side Effects Common side effects may include:

• Headache
• Muscle pain, back pain, joint pain
• Weight gain
• Peripheral oedema (swelling in ankles and feet)
• Upper respiratory tract infections, nasopharyngitis (common cold symptoms)
• Abnormal vision or vision problems

Serious side effects, though less common, can include symptoms of heart failure (e.g., unusual shortness of breath, rapid weight gain, localized swelling) and signs of bladder cancer (e.g., blood in urine, pain while urinating). Increased risk of fractures, particularly in women, has also been noted. Consult a doctor if any side effects persist or worsen.

Precautions TENDIA P TABLET is contraindicated in individuals with known hypersensitivity to its components, type 1 diabetes mellitus, diabetic ketoacidosis, active bladder cancer or a history of it, and severe kidney or liver disease. Caution is advised in patients with heart failure or a history of fluid retention, as pioglitazone may worsen these conditions. Regular monitoring of blood sugar levels and kidney function is crucial during treatment. Avoid excessive alcohol consumption as it may increase the risk of hypoglycemia. Inform your doctor about all other medications, supplements, or herbal remedies you are taking to avoid potential drug interactions. It is not recommended during pregnancy or breastfeeding.

Storage Store TENDIA P TABLET in a cool, dry place, protected from direct sunlight and moisture, at room temperature below 30°C (or between 10ºC to 25ºC). Keep the medicine out of reach and sight of children and pets.

What is TENDIA P TABLET used for?

TENDIA P TABLET is a combination medicine primarily used to manage type 2 diabetes mellitus in adults. It is prescribed when blood sugar levels cannot be adequately controlled with a single medicine, diet, and exercise alone. It helps improve glycemic control, enhances insulin sensitivity, and reduces the risk of serious diabetes complications like kidney damage and blindness.

How does TENDIA P TABLET work?

TENDIA P TABLET contains two active ingredients: Teneligliptin (20 mg) and Pioglitazone (15 mg). Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that prevents the breakdown of incretin hormones, which naturally increase insulin release after meals and reduce glucagon (a hormone that raises blood sugar). Pioglitazone is a thiazolidinedione that increases insulin sensitivity in muscle and fat cells, helping the body use insulin more effectively and reducing glucose production by the liver.

What is the usual dosage of TENDIA P TABLET?

The usual dosage of TENDIA P TABLET is one tablet taken orally once or twice daily, as prescribed by your doctor. It can be taken with or without food, but it is recommended to take it at the same time each day for consistent results. The dosage may vary based on your blood sugar levels and response to treatment, and you should not alter it without consulting your doctor.

What are the possible side effects of TENDIA P TABLET?

Common side effects of TENDIA P TABLET may include weight gain, peripheral oedema (swelling in ankles and feet), upper respiratory tract infections, headache, and nasopharyngitis (inflammation of nasal passages and throat). Other reported side effects can include low blood sugar (hypoglycemia), dizziness, muscle pain, back pain, and abnormal vision. If you experience any severe or persistent side effects, or symptoms like unusual shortness of breath, rapid weight gain, or blood in your urine, contact your doctor immediately.

Is TENDIA P TABLET safe during pregnancy or breastfeeding?

TENDIA P TABLET is generally contraindicated or not recommended during pregnancy and for breastfeeding women. If you are pregnant, planning to conceive, or breastfeeding, you should discuss this with your doctor to explore alternative anti-diabetic medications.

Can TENDIA P TABLET be taken with other medications?

TENDIA P TABLET can interact with certain medications. Strong CYP2C8 inhibitors like gemfibrozil may increase pioglitazone levels, potentially raising the risk of side effects. When combined with other antidiabetic medicines (e.g., metformin, insulin), it may increase the risk of low blood sugar (hypoglycemia). Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen may worsen fluid retention when taken with pioglitazone. Always inform your doctor about all other medications, supplements, and herbal remedies you are currently taking to avoid potential drug interactions.

What precautions should be taken while using TENDIA P TABLET?

You should inform your doctor if you have a history of heart failure, bladder cancer, or bone disorders, as TENDIA P TABLET may cause or worsen these conditions. Caution is also advised for patients with liver or kidney impairment. Avoid excessive alcohol consumption as it may affect blood sugar control and increase the risk of hypoglycemia. If you experience dizziness or confusion, avoid driving or operating machinery.

What happens if a dose of TENDIA P TABLET is missed?

If you miss a dose of TENDIA P TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this can lead to fluctuations in blood sugar.

How should TENDIA P TABLET be stored?

TENDIA P TABLET should be stored at room temperature, typically below 30°C, in its original container. Keep it in a dry place, away from direct sunlight and moisture, and out of reach of children and pets. Do not use the medicine after the expiry date printed on the package.