Esomac D 40mg Capsule (10 Cap)

ESOMAC D 40mg Capsule

ESOMAC D 40mg Capsule, manufactured by Cipla Ltd., is a combination medication used to manage various gastrointestinal conditions.

• Composition: Each hard gelatin capsule contains Esomeprazole Magnesium Trihydrate equivalent to Esomeprazole 40 mg (as enteric-coated pellets) and Domperidone IP 30 mg (as sustained-release pellets).
• Uses: It is primarily prescribed for adults to treat gastroesophageal reflux disease (GERD), especially when not responding to esomeprazole alone. It is also effective in managing peptic ulcers, Zollinger-Ellison syndrome, and associated symptoms like heartburn, acid indigestion, nausea, vomiting, bloating, and stomach pain.
• Dosage and Administration: ESOMAC D 40mg Capsule should be taken once daily, at least one hour before meals, or as advised by a physician. The capsules should be swallowed whole with liquid and should not be opened, chewed, or crushed.
• Side Effects: Common side effects may include headache, diarrhea, stomach pain, constipation, flatulence, nausea, vomiting, and dry mouth. Serious side effects can include severe allergic reactions, signs of liver problems, severe skin reactions, chest pain, irregular heartbeat, difficulty breathing, and fits.
• Precautions: Inform your doctor if you have liver, kidney, or heart problems, gut blockages or tears, weak bones, or are pregnant or breastfeeding. Long-term use may reduce vitamin B12 and magnesium levels, and increase the risk of bone fractures. It is contraindicated in patients with known hypersensitivity to its components, moderate to severe hepatic impairment, certain cardiac conditions, or prolactin-releasing pituitary tumors.
• Storage: Store below 25°C, protected from light and moisture. Keep out of reach of children.

What is ESOMAC D 40MG CAPSULE used for?

ESOMAC D 40MG CAPSULE is used to treat conditions like gastroesophageal reflux disease (GERD), which causes symptoms such as heartburn, acid reflux, and regurgitation. It also helps in managing stomach ulcers, duodenal ulcers, Zollinger-Ellison syndrome (a condition causing excessive stomach acid production), erosive esophagitis (inflammation of the food pipe), and functional dyspepsia (indigestion). It can also help relieve nausea, vomiting, bloating, burping, and general acidity-related discomfort.

How does ESOMAC D 40MG CAPSULE work?

ESOMAC D 40MG CAPSULE is a combination of two medicines: Esomeprazole and Domperidone. Esomeprazole is a proton pump inhibitor (PPI) that reduces the amount of acid produced in the stomach by blocking an enzyme called gastric proton pump, which is responsible for acid secretion. Domperidone is a prokinetic agent that works by increasing the movements and contractions of stomach muscles, allowing food to move more easily through the digestive system and preventing the backflow of stomach contents into the food pipe. It also helps to reduce nausea and vomiting by blocking dopamine receptors in the gut and brain.

What is the usual dosage for ESOMAC D 40MG CAPSULE?

Typically, ESOMAC D 40MG CAPSULE is taken once daily on an empty stomach, about 30 minutes to one hour before your first meal of the day. The capsule should be swallowed whole with water and not chewed, crushed, or broken. Your doctor will determine the correct dose and duration of treatment based on your specific medical condition, age, and body weight.

What are the possible side effects of ESOMAC D 40MG CAPSULE?

Common side effects may include dry mouth, stomach pain, diarrhea, headache, and flatulence. Other possible side effects can include nausea, vomiting, constipation, dizziness, and skin rash. Most of these side effects are temporary and usually resolve over time. However, if any of these side effects persist or worsen, you should consult your doctor. Long-term use may lead to low magnesium and vitamin B12 levels and might increase the risk of bone fractures.

Is ESOMAC D 40MG CAPSULE safe during pregnancy or breastfeeding?

Limited information is available regarding its safety during human pregnancy, and it should not be used during pregnancy unless absolutely necessary and advised by a doctor. If you are pregnant, planning pregnancy, or think you might be pregnant, consult your doctor. For breastfeeding mothers, small amounts of domperidone have been detected in breast milk, and it is generally considered unsafe or should be used only under medical supervision. Your doctor will weigh the benefits and potential risks before prescribing it.

Can ESOMAC D 40MG CAPSULE be taken with other medications?

You should inform your doctor about all other medications you are taking, as some may interact with ESOMAC D 40MG CAPSULE. Concomitant use with certain medications like nelfinavir (for HIV), atazanavir, amiodarone, clarithromycin (an antibiotic), ketoconazole (antifungal), verapamil (for high blood pressure), diazepam, phenytoin, digoxin, warfarin (blood-thinner), rifampicin, methotrexate, tacrolimus, voriconazole, cilostazol, clopidogrel, and apomorphine should be approached with caution or may not be recommended. Antacids can be taken if needed, but maintain a gap of at least 1 hour between taking ESOMAC D 40MG CAPSULE and antacids.

What precautions should be taken?

Inform your doctor if you have any allergies to the components of ESOMAC D 40MG CAPSULE, or if you have liver, kidney, or heart problems. Avoid consuming alcohol while taking this medicine, as it can worsen drowsiness and increase stomach acid production. This medicine may cause dizziness, so you should only drive or operate machinery if you are alert. Long-term use may require monitoring of magnesium and vitamin B12 levels and may increase the risk of bone fractures. ESOMAC D 40MG CAPSULE is generally not recommended for children as its safety and effectiveness have not been established.

What happens if a dose is missed?

If you miss a dose of ESOMAC D 40MG CAPSULE, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should ESOMAC D 40MG CAPSULE be stored?

ESOMAC D 40MG CAPSULE should be stored in a cool and dry place, below 25°C or 30°C, away from direct sunlight, moisture, and heat. Keep it out of sight and reach of children and pets.