Azovas T 40

AZOVAS T 40 Tablet

AZOVAS T 40 Tablet, manufactured by J B Chemicals and Pharmaceuticals Ltd, is a combination medication used for the management of high blood pressure.

• Composition

  • Azelnidipine (8 mg)
  • Telmisartan (40 mg)

• Uses AZOVAS T 40 Tablet is primarily prescribed for:

  • Treating hypertension (high blood pressure), especially stage II hypertension when single agents are not effective.
  • Reducing the risk of cardiovascular events such as heart attack and stroke.

• Dosage and Administration The recommended adult dose is one tablet once daily, or as directed by a physician. Tablets should be swallowed whole with liquid and not chewed, split, or crushed. It can be taken with or without food, preferably at the same time each day for optimal effectiveness.

• Side Effects Common side effects may include:

  • Dizziness
  • Headache
  • Nausea
  • Diarrhea
  • Fatigue
  • Peripheral oedema (swelling in the limbs)
  • Hypotension (low blood pressure) Most of these side effects are temporary and usually resolve over time.

• Precautions

  • Pregnancy and Breastfeeding: Contraindicated during the second and third trimesters of pregnancy due to potential harm to the fetus, and not recommended during breastfeeding.
  • Alcohol: Limit alcohol intake as it may increase blood pressure-lowering effects and lead to dizziness.
  • Liver/Kidney Impairment: Use with caution in patients with liver or kidney diseases; dose adjustments and careful monitoring may be necessary.
  • Driving: May cause dizziness or drowsiness, so caution is advised when driving or operating machinery.
  • Drug Interactions: Inform your doctor about all current medications, including potassium supplements, NSAIDs, other antihypertensives, lithium, digoxin, and certain antifungals or HIV protease inhibitors, as interactions can occur. Avoid grapefruit or grapefruit juice.

• Storage Store in a cool, dry place below 30°C, away from direct light and moisture, and out of the reach of children.

AZOVAS T 40, manufactured by J B Chemicals and Pharmaceuticals Ltd, is a combination medication used primarily for the treatment of high blood pressure (hypertension). It contains two active ingredients: Azelnidipine (8mg) and Telmisartan (40mg).

What is AZOVAS T 40 used for?

AZOVAS T 40 is prescribed to treat hypertension (high blood pressure). By effectively lowering blood pressure, it also helps in reducing peripheral resistance, relieving arterial stiffness, lowering the workload on the heart, and consequently, reducing the risk of cardiovascular events such as heart attacks and strokes.

How does AZOVAS T 40 work?

This medicine combines two different mechanisms to lower blood pressure. Azelnidipine, a calcium channel blocker, works by relaxing and widening the blood vessels, which increases blood supply to the heart and lowers elevated blood pressure. Telmisartan, an angiotensin II receptor blocker, blocks the action of certain substances in the body that cause blood vessels to constrict, thus promoting smoother blood flow and making the heart more efficient at pumping blood.

What is the usual dosage for AZOVAS T 40?

The recommended adult dose is typically one tablet once daily, or as directed by a physician. The dosage should be individualized based on the patient's medical condition and response to treatment. The tablet should be swallowed whole with water and should not be crushed, chewed, or broken. It can be taken with or without food, ideally at the same time each day for optimal effectiveness.

What are the possible side effects of AZOVAS T 40?

Common side effects may include dizziness, headache, nausea, diarrhea, fatigue, peripheral oedema (swelling in the limbs due to fluid retention), and hypotension (low blood pressure). Most of these side effects are usually mild and resolve over time, but if they persist or worsen, it's important to consult your doctor.

Is AZOVAS T 40 safe during pregnancy or breastfeeding?

AZOVAS T 40 is generally not considered safe during pregnancy, especially in the second and third trimesters, as it can cause serious harm or even be fatal to the developing fetus. It should be discontinued as soon as possible if pregnancy is detected. For breastfeeding mothers, there is limited information available, and it is advised to consult your doctor to weigh the benefits against potential risks to the infant.

Can AZOVAS T 40 be taken with other medications?

AZOVAS T 40 can interact with several medications. Concomitant use with other blood pressure-lowering medicines may lead to a significant drop in blood pressure. It is contraindicated with azole antifungals (e.g., itraconazole, miconazole) and HIV protease inhibitors (e.g., ritonavir, saquinavir, indinavir). Caution is advised with lithium, digoxin, and CYP3A4 inhibitors (e.g., erythromycin, diltiazem). Additionally, its use with aliskiren-containing products is contraindicated in patients with diabetes mellitus or renal impairment. It's crucial to inform your doctor about all other medications, herbal preparations, and supplements you are taking.

What precautions should be taken while using AZOVAS T 40?

It is advised to limit alcohol consumption while taking AZOVAS T 40, as it may increase the risk of low blood pressure and adverse effects such as dizziness. The medication may cause dizziness or weakness, so caution should be exercised when driving or operating machinery until you know how it affects you. Patients with kidney or liver conditions should use this medicine with caution and may require regular monitoring of kidney function, electrolytes, and liver function. Do not stop taking the medicine abruptly without consulting your doctor, as this can lead to changes in blood pressure.

What happens if a dose of AZOVAS T 40 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should AZOVAS T 40 be stored?

AZOVAS T 40 should be stored in a cool, dry place, away from direct light and moisture. The ideal storage temperature is typically below 30°C. Keep it out of the sight and reach of children, and always check the expiration date on the packaging before use.