Daxid 25 Mg Tablet (15 Tab)

DAXID 25 MG TABLET is an antidepressant medication manufactured by Pfizer Limited. It is primarily used for various mental health conditions by balancing specific chemical messengers in the brain.

Name

• Common Name: Sertraline Tablet
• Brand Name: DAXID 25 MG TABLET

Composition

Each tablet contains Sertraline equivalent to 25 mg. Sertraline is classified as a Selective Serotonin Reuptake Inhibitor (SSRI) antidepressant, which works by increasing serotonin levels in the brain to improve mood, behavior, and emotions.

Uses

DAXID 25 MG TABLET is prescribed for the treatment of several medical conditions:

• Depression (including major depressive disorder and prevention of recurrence)
• Obsessive-Compulsive Disorder (OCD), including in children aged 6-17 years
• Panic Disorder, with or without agoraphobia
• Post-Traumatic Stress Disorder (PTSD)
• Social Anxiety Disorder (Social Phobia)
• Premenstrual Dysphoric Disorder (PMDD)

Dosage and Administration

DAXID 25 MG TABLET should be taken orally once daily, either in the morning or evening, with or without food, as advised by a doctor.

• Initial Dosage: For panic disorder, PTSD, and social phobia, therapy typically starts at 25 mg/day, increasing to 50 mg/day after one week. For depression and OCD, the initial dose is generally 50 mg/day.
• Maintenance: Doses may be gradually increased by 25-50 mg/day at intervals of at least one week, up to a maximum of 200 mg/day, based on therapeutic response and tolerability.
• Do not suddenly stop taking the medicine, as this can lead to withdrawal symptoms.

Side Effects

Common Side Effects:

• Nausea, indigestion, loss of appetite
• Diarrhea, headache, dizziness, drowsiness
• Increased sweating, tremors, insomnia (difficulty sleeping), fatigue
• Dry mouth, changes in taste
• Sexual dysfunction, including decreased libido, delayed ejaculation, and erectile dysfunction

Serious Side Effects:

• Thoughts of self-harm or suicide (especially at the beginning of treatment or with dose changes)
• Severe dizziness, lightheadedness, fainting, sudden changes in heart rhythm
• Allergic reactions (e.g., skin rash, swelling of the face/lips/throat, difficulty breathing)
• Liver damage, low sodium levels (hyponatremia), seizures
• Serotonin syndrome (symptoms include agitation, hallucinations, rapid heartbeat, fever, overactive reflexes, nausea, vomiting, diarrhea)

Precautions

• Allergies: Do not take if allergic to sertraline or any other components of the tablet.
• Drug Interactions: Avoid concomitant use with Monoamine Oxidase Inhibitors (MAOIs) like moclobemide and methylene blue, and pimozide, due to the risk of severe adverse effects. Inform your doctor about all medications, including herbal supplements (e.g., St. John's Wort), to avoid potential interactions.
• Medical Conditions: Use with caution in patients with diabetes, epilepsy/seizures, bipolar disorder, bleeding disorders, glaucoma, liver or kidney disease, heart problems, or a history of low sodium or potassium levels.
• Pregnancy and Breastfeeding: Not recommended during pregnancy, especially in the last trimester, due to potential risks to the baby (e.g., persistent pulmonary hypertension of the newborn). It may be excreted in human milk. Consult a doctor if pregnant, planning pregnancy, or breastfeeding.
• Alcohol and Grapefruit Juice: Avoid alcohol consumption as it can worsen side effects such as drowsiness and dizziness. Avoid grapefruit juice as it may increase the level of sertraline in the body.
• Driving and Operating Machinery: This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you.
• Discontinuation: Do not stop treatment abruptly without consulting a doctor, even if symptoms improve, as it can lead to withdrawal symptoms.

Storage

Store in a cool and dry place, below 30°C, away from direct sunlight. Protect from moisture and light. Keep out of sight and reach of children.

DAXID 25 MG TABLET (15 TAB) by PFIZER LIMITED contains Sertraline, a selective serotonin reuptake inhibitor (SSRI) antidepressant. It is commonly prescribed for various mental health conditions.

What is DAXID 25 MG TABLET used for?

DAXID 25 MG TABLET is primarily used to treat major depressive disorder and prevent its recurrence. It is also effective in managing various anxiety-related conditions, including obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder (social phobia), post-traumatic stress disorder (PTSD), generalized anxiety disorder, and premenstrual dysphoric disorder (PMDD). For children aged 6 to 17 years, it is specifically indicated for obsessive-compulsive disorder.

How does DAXID 25 MG TABLET work?

DAXID 25 MG TABLET works by increasing the levels of serotonin, a natural chemical messenger in the brain. Serotonin plays a crucial role in regulating mood, behavior, and emotions. By inhibiting the reabsorption of serotonin back into nerve cells, this medication helps to rebalance brain chemicals, thereby improving mood, relieving anxiety, and aiding in better sleep and energy levels.

What is the usual dosage for DAXID 25 MG TABLET?

The usual dosage is determined by your doctor based on your age, body weight, and the specific condition being treated. For adults and pediatric patients, the initial therapeutic dosage is typically 25 mg or 50 mg per day. The dosage may be increased in increments of 25 to 50 mg per day once a week, depending on your response and tolerability, up to a maximum of 200 mg per day. It is generally taken once a day, with or without food, preferably at the same time each day.

What are the possible side effects of DAXID 25 MG TABLET?

Common side effects may include nausea, indigestion, loss of appetite, increased sweating, tremors, insomnia (difficulty sleeping), dizziness, dry mouth, headache, fatigue, and diarrhea. Sexual side effects like decreased libido, delayed ejaculation, and erectile dysfunction may also occur. More serious, but rare, side effects can include sudden worsening of mood or thoughts of self-harm, especially in individuals under 25 years old. Inform your doctor if any side effects persist or worsen.

Is DAXID 25 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: DAXID 25 MG TABLET (sertraline) can be taken during pregnancy, but it's important to consult your doctor. Some studies suggest a small, potential risk of congenital heart defects in the baby, particularly if taken during the first trimester, and short-term withdrawal symptoms or breathing problems if taken in the weeks before delivery. Taking it in the last month of pregnancy may also slightly increase the risk of bleeding after delivery. Your doctor will weigh the benefits against potential risks.

Breastfeeding: Sertraline is considered one of the preferred antidepressants for breastfeeding mothers due to its low levels in breast milk. Very small amounts pass into breast milk and have been linked with side effects in very few breastfed babies. However, it is advisable to monitor the baby for any changes in sleeping habits, eating, fussiness, rash, or breathing problems.

Can DAXID 25 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all other medications you are taking, as DAXID 25 MG TABLET can interact with several drugs. It should not be taken with monoamine oxidase inhibitors (MAOIs), such as moclobemide, as this combination can lead to severe adverse effects or a potentially life-threatening condition called serotonin syndrome. Caution is also advised with other antidepressants, antiplatelet agents (e.g., aspirin, clopidogrel), anticoagulants (e.g., warfarin, heparin), certain migraine medications (triptans), some pain relievers (e.g., tramadol, ibuprofen), and St. John's Wort.

What precautions should be taken while using DAXID 25 MG TABLET?

Before starting DAXID 25 MG TABLET, inform your doctor about any pre-existing medical conditions, including epilepsy (seizure disorder), diabetes, liver or kidney disease, heart problems, glaucoma, bleeding disorders, or low sodium levels. Do not abruptly stop taking this medication, as it can lead to unpleasant withdrawal symptoms like dizziness, anxiety, restlessness, and sleep disturbances. Since it may cause drowsiness or dizziness, it is not recommended to drive or operate heavy machinery until you understand how the medicine affects you. Alcohol consumption should be avoided while taking this medication.

What happens if a dose of DAXID 25 MG TABLET is missed?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.

How should DAXID 25 MG TABLET be stored?

DAXID 25 MG TABLET should be stored in a cool, dry place, away from direct sunlight, and at room temperature (below 30°C). Keep it out of the sight and reach of children and pets. Protect it from moisture and light.