Panderm Super 15 Gm Cream

PANDERM SUPER 15 GM CREAM is a topical medication manufactured by Macleods Pharmaceuticals Ltd., formulated to address various skin infections.

Name:

• Brand Name: Panderm Super Cream

Composition: Panderm Super Cream contains a combination of three active ingredients:

• Clobetasol (0.05% w/w): A highly potent corticosteroid with anti-inflammatory, antipruritic (itching-relieving), and vasoconstrictive properties. It works by blocking chemical mediators that cause redness, swelling, and itching.
• Clotrimazole (1% w/w): An antifungal medication that inhibits the growth of fungi by damaging and leaking their cell membranes.
• Fusidic Acid (2% w/w): An antibacterial/antibiotic that prevents bacterial growth by hindering the synthesis of essential proteins required for bacteria to function.

Uses: This cream is primarily used to treat a wide range of skin infections caused by bacteria and fungi, often associated with inflammation. It is prescribed for conditions such as:

• Eczema (inflamed, itchy, cracked skin patches)
• Dermatitis (skin inflammation)
• Psoriasis (rapidly multiplying skin cells forming red, scaly patches)
• Ringworm
• Athlete's foot
• Jock itch
• Lichen planus (inflammation of skin and mucous membranes)
• Tinea versicolor (discolored patches on the skin)
• Bacterial infections like impetigo and folliculitis

Dosage and Administration: Panderm Super Cream is for external use only. A thin layer should be applied to the clean, dry affected area of the skin, typically twice daily, or as advised by a doctor. The duration of treatment is generally for a limited period, often around 2 weeks, to avoid potential side effects from prolonged corticosteroid use. Hands should be washed before and after application unless the treatment area is the hands.

Side Effects: Common side effects at the application site include:

• Burning sensation
• Irritation
• Itching
• Redness
• Thinning of the skin (with prolonged use)

Serious side effects, though rare, can occur with prolonged or excessive use of the corticosteroid component, such as skin atrophy, stretch marks, widening of small blood vessels, acne, or changes in skin pigmentation. If these or other severe reactions occur, discontinue use and consult a doctor.

Precautions:

• Avoid contact with eyes, nose, mouth, or other mucous membranes. If accidental contact occurs, rinse thoroughly with water.
• Do not apply to open wounds, ulcers, or damaged skin.
• Do not cover the treated area with bandages or occlusive dressings unless specifically advised by a doctor, as this can increase the absorption and risk of side effects.
• Not recommended for use on the face for extended periods, or for children under 12 years of age without strict medical supervision.
• Inform your doctor if you have a history of liver or kidney diseases, glaucoma, cataract, diabetes, or immune system problems.
• Use with caution during pregnancy and breastfeeding, only if deemed necessary by a healthcare professional.
• Avoid using it for viral skin infections (e.g., herpes, chickenpox) or for acne and rosacea.

Storage: Store Panderm Super Cream below 25°C. Keep it in its original packaging and out of reach of children.

PANDERM SUPER 15 GM CREAM is a topical medication containing a combination of Clobetasol, Clotrimazole, and Fusidic Acid. It is manufactured by Macleods Pharmaceuticals Ltd. This cream is primarily used to treat various skin infections that involve inflammation, itching, and bacterial or fungal components.

What is Panderm Super Cream used for?

Panderm Super Cream is used to treat a wide range of skin infections and inflammatory skin conditions. These include eczema, dermatitis, psoriasis, ringworm, athlete's foot, jock itch, lichen planus, and tinea versicolor. It helps in relieving symptoms such as inflammation, itching, redness, and swelling associated with these conditions.

How does Panderm Super Cream work?

Panderm Super Cream is a combination of three active ingredients: Clobetasol, Clotrimazole, and Fusidic acid.

• Clobetasol is a potent corticosteroid that reduces inflammation, itching, and narrows blood vessels by blocking the production of chemical mediators (like prostaglandins) that cause redness, swelling, and itching in the skin.
• Clotrimazole is an antifungal medication that works by stopping the growth of fungi. It achieves this by damaging and causing leakage in the fungal cell membrane.
• Fusidic acid is an antibacterial (antibiotic) that inhibits the growth of bacteria by preventing them from synthesizing essential proteins needed for their vital functions. The combined action of these ingredients provides comprehensive treatment against inflammation, bacterial infections, and fungal infections.

What is the usual dosage for Panderm Super Cream?

Panderm Super Cream is for external use only. It should be applied as a thin layer to the clean and dry affected skin area, typically once or twice daily, or as advised by your doctor. The exact dosage and duration of treatment will depend on the specific condition and should be followed strictly as prescribed by your doctor, usually for up to two weeks.

What are the possible side effects of Panderm Super Cream?

Common side effects at the application site may include burning, irritation, itching, redness, and thinning of the skin. These side effects are usually temporary and resolve over time. However, if they persist or worsen, you should consult your doctor. Prolonged or excessive use of this cream, especially on large areas, can lead to increased systemic absorption of Clobetasol, potentially causing more serious side effects like adrenal suppression, Cushing's syndrome (characterized by weight gain, high blood pressure, facial rounding), skin discoloration, visible veins, and increased hair growth.

Is Panderm Super Cream safe during pregnancy or breastfeeding?

Pregnancy: Panderm Super Cream should be used with caution during pregnancy and only if clearly necessary, after consulting your doctor. Limited human studies are available, but animal studies have shown potential harmful effects on the developing baby. Your doctor will weigh the benefits against the potential risks before prescribing.

Breastfeeding: It should be used with caution in breastfeeding women, and only if deemed necessary by a doctor. Information regarding its use during breastfeeding is limited or not readily available. If applied to the breasts, care should be taken to avoid applying it shortly before feeding, and the baby's skin should not come into direct contact with the treated area.

Can Panderm Super Cream be taken with other medications?

Since Panderm Super Cream is a topical medication, its systemic absorption into the body is minimal, making interactions with orally taken medications unlikely under normal use. However, it is always important to inform your doctor about all other medications, including other topical products, prescription, non-prescription, or herbal medicines you are currently using to prevent any potential interactions or complications. Applying the cream over large skin areas or under airtight dressings can increase systemic absorption, which might raise the risk of interactions.

What precautions should be taken while using Panderm Super Cream?

• Always use Panderm Super Cream exactly as prescribed by your doctor.
• Wash your hands thoroughly before and after applying the cream, unless your hands are the treated area.
• Avoid contact with your eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse the area thoroughly with water.
• Do not apply the cream to the face for more than five days, and avoid using it on broken or infected skin unless specifically directed by a healthcare professional.
• Do not cover the treated area with bandages or occlusive dressings unless your doctor advises you to do so, as this can increase absorption and potential side effects.
• Complete the full course of treatment even if your symptoms improve earlier, to ensure the infection is fully cleared and to prevent recurrence.
• Avoid overuse or prolonged use, as this can lead to skin thinning and other serious side effects.
• Panderm Super Cream is not recommended for individuals with known allergies to its components, or those with viral skin infections (such as herpes or chickenpox), acne, or rosacea.
• It is generally not recommended for diaper rash or in children under two years of age.
• Inform your doctor if you have any history of liver or kidney diseases, glaucoma, cataract, poor blood circulation, immune system problems, diabetes, or adrenal gland diseases.

What happens if a dose is missed?

If you miss an application of Panderm Super Cream, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular application schedule. Do not apply a double dose to compensate for the missed one.

How should Panderm Super Cream be stored?

Store Panderm Super Cream in its original packaging at room temperature, ideally below 25°C, away from direct sunlight and heat. Ensure it is kept out of the reach of children and pets. Dispose of any unused medicine safely according to local guidelines.