Pregeb M 75 Mg Capsule (10 Cap)

PREGEB M 75 MG CAPSULE

Name: Pregeb M 75 Capsule is a brand-name medicine manufactured by Torrent Pharmaceuticals Ltd.. Its common name refers to its active ingredients, Pregabalin and Methylcobalamin.

Composition: Each capsule contains Pregabalin 75 mg and Methylcobalamin 750 mcg.

Uses: Pregeb M 75 Capsule is primarily prescribed for the treatment of neuropathic pain, which is nerve pain resulting from nerve damage or nervous system malfunction. This includes conditions such as:

• Diabetic neuropathy.
• Postherpetic neuralgia (nerve pain after shingles).
• Peripheral neuropathy (weakness, numbness, and pain, often in hands and feet).
• Fibromyalgia symptoms.

It may also offer benefits for anxiety relief, general pain management, improved sleep quality, and mood stabilization.

Dosage and Administration: Pregeb M 75 Capsule is taken orally as directed by a doctor, typically once or twice daily, with or without food, and preferably at bedtime. It should be swallowed whole with water and not crushed, broken, or chewed. Treatment should not be discontinued abruptly without consulting a physician to avoid withdrawal symptoms.

Side Effects: Common side effects include:

• Dizziness, drowsiness, and fatigue.
• Headache.
• Nausea, vomiting, diarrhea, constipation, or loss of appetite.
• Blurred vision or other vision problems.
• Weight gain.
• Swelling in ankles and feet (oedema).

Serious side effects, though rare, can include mood changes (depression, suicidal thoughts), severe allergic reactions (e.g., swelling of the face, lips, or tongue), heart problems, and kidney issues.

Precautions:

• Not recommended for children and adolescents under 18 years of age.
• Use with caution in pregnant or breastfeeding women; consult a doctor as benefits should outweigh risks.
• Avoid alcohol consumption as it can increase drowsiness and affect coordination.
• May cause dizziness and drowsiness, so avoid driving or operating heavy machinery until you understand how it affects you.
• Caution is advised for patients with kidney or liver diseases, heart conditions, or diabetes.
• Discontinuation should be gradual under medical supervision to prevent withdrawal symptoms.

Storage: Store in a cool, dry place, away from direct sunlight and moisture, preferably below 25°C or 30°C. Keep out of sight and reach of children.

PREGEB M 75 MG CAPSULE is a combination medication containing Pregabalin and Methylcobalamin (Vitamin B12). It is primarily used to treat neuropathic pain, which is pain caused by nerve damage.

Here are some frequently asked questions about PREGEB M 75 MG CAPSULE:

What is PREGEB M 75 MG CAPSULE used for?

PREGEB M 75 MG CAPSULE is prescribed for the treatment of neuropathic pain in adults. This includes nerve pain caused by conditions such as diabetes (diabetic neuropathy), shingles (postherpetic neuralgia), spinal cord injury, and peripheral neuropathy. It may also be used to manage fibromyalgia symptoms, control certain types of seizures, and help with anxiety and sleep disturbances associated with pain.

How does PREGEB M 75 MG CAPSULE work?

This medicine combines two active ingredients: Pregabalin and Methylcobalamin.

• Pregabalin works by binding to a specific site on voltage-gated calcium channels in the central nervous system. This action reduces the release of certain neurotransmitters (chemical messengers) that send pain signals across the nervous system, thereby decreasing pain sensation.
• Methylcobalamin is an active form of Vitamin B12. It helps in the formation of myelin, a protective sheath around nerve fibers, and supports the regeneration and protection of damaged nerve cells. Together, these components help relieve nerve pain and improve nerve signal conduction.

What is the usual dosage of PREGEB M 75 MG CAPSULE?

The dosage and duration of treatment are determined by your doctor based on your medical condition and response to treatment. It is typically taken orally, with or without food, often once or twice daily, preferably at bedtime, to maintain consistent levels in the body. Always follow your doctor's instructions and do not stop taking it abruptly.

What are the possible side effects of PREGEB M 75 MG CAPSULE?

Common side effects include dizziness, drowsiness, tiredness, blurred vision, headache, dry mouth, nausea, vomiting, diarrhea, constipation, increased appetite, and weight gain. These side effects are usually temporary and tend to resolve over time. More serious but rare side effects can include severe allergic reactions (skin rash, swelling of face/lips/throat, difficulty breathing), mood changes, depression, and suicidal thoughts. If you experience persistent or severe side effects, or any unusual mood changes, contact your doctor immediately.

Is it safe during pregnancy or breastfeeding?

PREGEB M 75 MG CAPSULE is generally not recommended during pregnancy as there is limited data on its safety, and animal studies have shown potential risks to the fetus. Women of childbearing potential are advised to use effective contraception during treatment. It is also not recommended during breastfeeding, as it may pass into breast milk and could harm the baby. Always consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Can it be taken with other medications?

PREGEB M 75 MG CAPSULE can interact with certain other medications, potentially affecting their action or increasing side effects. Inform your doctor about all medicines you are currently taking, including prescribed, over-the-counter, herbal medicines, and dietary supplements. Specific interactions have been noted with ACE inhibitors, antidepressants, antihistamines, medications for anxiety (like lorazepam), medications for mental illness or seizures, certain diabetes medications (like pioglitazone, rosiglitazone), opioid pain medications (like hydrocodone, morphine, oxycodone), sedatives, and sleeping pills.

What precautions should be taken?

• Alcohol: Avoid consuming alcohol as it can increase drowsiness, dizziness, and impair motor skills.
• Driving & Operating Machinery: This medicine can cause dizziness, drowsiness, and blurred vision, affecting your ability to drive or operate heavy machinery.
• Kidney/Liver Disease: Use with caution if you have impaired kidney or liver function, as dose adjustments or alternative treatments may be necessary.
• Discontinuation: Do not stop taking the medicine abruptly without consulting your doctor, as it can lead to withdrawal symptoms such as anxiety, fatigue, sweating, vomiting, depression, seizures, and hallucinations.
• Elderly Patients: Elderly patients may require dose reductions due to decreased renal function and are at higher risk of accidental injury (falls) due to dizziness or sleepiness.
• Suicidal Tendencies: Monitor mood and behavior, as the medication may rarely cause suicidal thoughts. Report any such changes to your doctor immediately.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may increase the risk of side effects.

How should it be stored?

Store PREGEB M 75 MG CAPSULE at room temperature, below 25°C or 30°C, in a cool and dry place. Protect it from light and moisture, and keep it out of reach of children and pets.