Adilip 45 Mg Tablet (10 Tab)

ADILIP 45 MG TABLET

ADILIP 45 MG TABLET, manufactured by Intas Pharmaceuticals Ltd., is a medication primarily used to manage high cholesterol and triglyceride levels. It belongs to a class of drugs known as fibrates.

• Name: ADILIP 45 MG TABLET (brand name, also referred to as Adilip 45 Tablet DR).

• Composition: Each tablet contains Fenofibrate 45 mg (also referred to as Choline Fenofibrate).

• Uses: ADILIP 45 MG TABLET is prescribed for conditions associated with elevated lipid levels, including:

  • Hyperlipidemia (high cholesterol).
  • Severe hypertriglyceridemia (very high triglyceride levels in the blood).
  • Primary hypercholesterolemia.
  • Mixed dyslipidemia (high triglyceride and cholesterol levels). It works by lowering "bad" cholesterol (LDL) and triglycerides while increasing "good" cholesterol (HDL), thereby reducing the risk of heart attacks and strokes.

• Dosage and Administration:

  • Typically taken once daily with food, as advised by a doctor.
  • Swallow the tablet whole; do not chew, crush, or break it.
  • Maintain a consistent daily schedule for taking the medication.
  • Dosage and duration are determined by the doctor based on the individual's condition, age, and response to therapy.
  • Not recommended for children and adolescents under 18 years of age.

• Side Effects:

  • Common: Nausea, abdominal pain, diarrhea, vomiting, headache, back pain, flatulence, increased liver enzymes, and inflammation of the nose.
  • Serious (seek immediate medical attention if experienced): Unexplained muscle pain, tenderness, or weakness (especially if accompanied by fever, as this could indicate myopathy or rhabdomyolysis), severe skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, or DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms).

• Precautions:

  • Inform your doctor about any allergies to fenofibrate or other medications.
  • Contraindicated in patients with active liver disease, severe kidney impairment (including those on dialysis), pre-existing gallbladder disease, or a history of photoallergic reactions to fibrates or ketoprofen.
  • Use with caution in patients with kidney or liver disease, requiring regular monitoring of liver and kidney function.
  • Pregnancy and Breastfeeding: Consult a doctor; generally not recommended for breastfeeding women.
  • Alcohol: Avoid or limit alcohol consumption as it may increase the risk of muscle and liver problems.
  • Drug Interactions: Inform your doctor about all other medications, including anticoagulants (e.g., warfarin), immunosuppressants (e.g., cyclosporine), bile acid sequestrants (e.g., cholestyramine), and statins, as interactions can occur.
  • Adilip 45 MG TABLET is part of a comprehensive treatment plan that should also include a healthy diet, regular exercise, smoking cessation, and weight management.

• Storage: Store at room temperature, ideally below 25°C or 30°C. Keep the medicine in its original, tightly-closed container, protected from light and moisture, and out of reach of children.

What is ADILIP 45 MG TABLET used for?

ADILIP 45 MG TABLET is primarily used to manage high levels of cholesterol and triglycerides in the blood. It helps in reducing "bad" cholesterol (LDL) and total cholesterol, while simultaneously increasing "good" cholesterol (HDL). This medication is prescribed as an adjunct to diet and exercise to lower the risk of cardiovascular events like heart attacks and strokes.

How does ADILIP 45 MG TABLET work?

ADILIP 45 MG TABLET contains Fenofibrate (45 mg). It works by activating a specific nuclear receptor called PPARα, which helps regulate genes involved in fat metabolism. This action increases the breakdown of triglyceride-rich lipoproteins, thereby reducing triglyceride levels, and also helps the body produce more HDL ("good" cholesterol).

What is the usual dosage of ADILIP 45 MG TABLET?

For adults, the recommended starting dose is typically 10-20 mg once daily, which may be increased up to 80 mg once daily based on the individual's response and medical condition. It should be taken orally, preferably at the same time each day, with or without food, though some sources recommend taking it with food for optimal results. For children aged 10 to 17 years, the dosage depends on the child's weight and medical condition, usually starting at 10 mg once daily with a maximum recommended dose of 20 mg once daily. It is not recommended for children under 10 years of age.

What are the possible side effects of ADILIP 45 MG TABLET?

Common side effects can include abdominal pain, diarrhea, nausea, headache, flatulence, vomiting, and back pain. Some patients may experience increased liver enzymes or increased creatine phosphokinase (CPK) levels in the blood. Serious but rare side effects include severe skin reactions, unexplained muscle pain, tenderness, cramps, or weakness (especially if accompanied by fever), and signs of liver problems like unusual fatigue, loss of appetite, yellowing of the eyes or skin (jaundice), or dark urine. It is important to consult a doctor if any side effects persist or cause concern.

Is ADILIP 45 MG TABLET safe during pregnancy or breastfeeding?

ADILIP 45 MG TABLET should be used with caution during pregnancy and only if clearly advised by a doctor, as animal studies have shown potential risks to the developing baby. It is generally not recommended for use during breastfeeding, as minimal human data suggests potential transfer of the drug into breast milk, posing a risk to the baby.

Can ADILIP 45 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all other medications you are currently taking to avoid potential drug interactions. ADILIP 45 MG TABLET can interact with:

• Oral anticoagulants (blood thinners) like warfarin, increasing the risk of bleeding.
• Immunosuppressants such as cyclosporine, which may increase the risk of kidney toxicity.
• Other cholesterol-lowering medications (statins) like atorvastatin, rosuvastatin, pravastatin, fluvastatin, or simvastatin, as this can increase the risk of muscle disorders.
• Bile-acid binding resins like cholestyramine; ADILIP 45 MG TABLET should be taken at least 1 hour before or 4-6 hours after taking these.
• Anti-diabetic agents and colchicine.
• Oral contraceptives containing estrogen may reduce the effects of ADILIP 45 MG TABLET.

What precautions should be taken with ADILIP 45 MG TABLET?

• Avoid consuming alcohol, as it can increase the risk of liver problems and muscle-related issues.
• Inform your doctor if you have a history of kidney or liver disease, pre-existing gallbladder disease, or hypothyroidism, as the medication may not be suitable or may require dose adjustments.
• Regular monitoring of liver function and lipid levels is essential during treatment.
• Report any unexplained muscle pain, tenderness, cramps, or weakness to your doctor promptly.

What happens if a dose of ADILIP 45 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

How should ADILIP 45 MG TABLET be stored?

ADILIP 45 MG TABLET should be stored at room temperature, ideally below 25°C or 30°C. Keep it in its original, tightly-closed container to protect it from light and moisture, and always out of reach of children and pets. Ensure to use the medicine before its expiry date.