Rablet It Capsule (10 Cap)

RABLET IT CAPSULE (10 CAP) by LUPIN LTD.

RABLET IT CAPSULE is a combination medication manufactured by Lupin Ltd., designed to address a range of gastrointestinal issues related to excess stomach acid and impaired gut motility.

Composition

RABLET IT CAPSULE contains two active ingredients:

• Rabeprazole (20mg): A proton pump inhibitor (PPI) that works by significantly reducing the amount of acid produced in the stomach.
• Itopride (150mg): A prokinetic agent that enhances the movement of food through the digestive tract, particularly by increasing gastric emptying and improving gastrointestinal motility. It also possesses antiemetic (anti-vomiting) properties.

Uses

This medication is primarily prescribed for the treatment and management of:

• Gastroesophageal Reflux Disease (GERD), also known as acid reflux, which causes heartburn and irritation of the food pipe.
• Peptic Ulcer Disease, including stomach ulcers.
• Hyperacidity and associated symptoms like heartburn and gas.
• Erosive Esophagitis.
• Functional Dyspepsia, characterized by chronic upper abdominal discomfort, bloating, and early satiety.
• Zollinger-Ellison Syndrome.
• Managing nausea and discomfort caused by indigestion.

Dosage and Administration

RABLET IT CAPSULE should be taken orally, generally once daily, as advised by your doctor. It can be taken with or without food, though some doctors may suggest taking it approximately 30 minutes before a meal, preferably in the morning, for optimal results. The capsule should be swallowed whole with a glass of water and not cut, broken, or chewed. It is crucial to adhere to the prescribed dose and duration; do not take more than recommended. If a dose is missed, take it as soon as you remember, but skip it if it's almost time for the next dose. Do not take a double dose.

Side Effects

Common side effects may include:

• Headache
• Nausea and stomach pain (abdominal pain)
• Diarrhea or constipation
• Dizziness
• Flatulence (gas)
• Increased saliva production
• Rash or itching
• Flu-like symptoms, weakness, and back pain

Serious but rare side effects can include severe allergic reactions, liver problems, signs of low magnesium levels (muscle spasms, irregular heartbeat), osteoporosis with long-term use, and vitamin B12 deficiency. Consult your doctor if any side effects persist or worsen.

Precautions

• Allergies: Do not take if you are allergic to rabeprazole, itopride, or any similar medications.
• Pregnancy and Breastfeeding: RABLET IT CAPSULE is generally avoided during pregnancy and breastfeeding unless specifically prescribed by a doctor due to limited safety data.
• Medical Conditions: Inform your doctor if you have liver or kidney problems, a history of gastrointestinal bleeding, obstruction, perforation, or a stomach tumor.
• Driving and Alcohol: Avoid driving or operating heavy machinery if you experience dizziness. It is advisable to avoid alcohol consumption as it may worsen acidity and increase drowsiness.
• Children: This medicine is not recommended for children under 12 years of age.
• Long-Term Use: Prolonged use may lead to a deficiency of vitamin B12, low magnesium levels (hypomagnesemia), and an increased risk of osteoporosis.
• Drug Interactions: Inform your doctor about all other medications, supplements, and herbal products you are taking, especially anticoagulants (e.g., warfarin), HIV medications (e.g., atazanavir), digoxin, methotrexate, and certain antifungals (e.g., ketoconazole).

Storage

Store RABLET IT CAPSULE in a cool and dry place, protected from direct sunlight, moisture, and heat, ideally between 10°C to 25°C or below 30°C. Keep it out of the sight and reach of children and pets. Do not freeze the medicine. Dispose of any unused medicine properly.

Here are frequently asked questions about Rablet IT Capsule:

What is Rablet IT Capsule used for?

Rablet IT Capsule is primarily used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and other conditions involving excessive stomach acid production. It helps relieve symptoms like heartburn, acid reflux, stomach pain, irritation, bloating, discomfort, and nausea, and can also be used for functional dyspepsia.

How does Rablet IT Capsule work?

Rablet IT Capsule is a combination of two active ingredients: Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking a specific enzyme system in the stomach lining, thereby reducing the amount of acid produced. Itopride is a prokinetic agent that enhances the movement of food through the digestive tract by increasing stomach and intestinal motility, and also helps control vomiting.

What is the usual dosage for Rablet IT Capsule?

The dosage of Rablet IT Capsule is determined by your doctor based on your specific condition and how you respond to the medicine. It is typically taken once a day, preferably one hour before a meal, often in the morning. The capsule should be swallowed whole with a glass of water and not crushed, broken, or chewed.

What are the possible side effects of Rablet IT Capsule?

Common side effects can include headache, nausea, stomach pain, dizziness, diarrhea, constipation, flatulence (gas), increased saliva production, weakness, flu-like symptoms, rash, and back pain. More serious, though rare, side effects may include severe allergic reactions, severe stomach pain, bloody diarrhea, signs of liver problems (yellowing of the skin or eyes, dark urine), or signs of low magnesium levels (muscle spasms, irregular heartbeat, seizures). Long-term use may also lead to osteoporosis, hypomagnesemia, and vitamin B12 deficiency.

Is Rablet IT Capsule safe during pregnancy or breastfeeding?

Rablet IT Capsule is generally not recommended for use during pregnancy or breastfeeding. Caution is advised, and you should consult your doctor to discuss the potential risks and benefits before taking this medicine if you are pregnant or breastfeeding.

Can Rablet IT Capsule be taken with other medications?

It is important to inform your doctor about all medications, supplements, and herbal remedies you are currently taking. Rablet IT Capsule can interact with certain medicines, including anticoagulants (like warfarin, aspirin), antifungal medicines (such as ketoconazole, itraconazole), methotrexate, HIV medicines (like atazanavir), and digoxin. Avoid taking it with St. John's wort. You can generally take it with antacids, but if you are taking sucralfate, ensure at least a 30-minute gap.

What precautions should be taken while using Rablet IT Capsule?

Inform your doctor if you have any allergies to rabeprazole, itopride, or similar medications. Exercise caution if you have a history of gastrointestinal bleeding, obstruction, perforation, a stomach tumor, liver disease, or kidney impairment. Long-term use of this medicine may increase the risk of osteoporosis, low magnesium levels, and vitamin B12 deficiency. Rablet IT Capsule may cause dizziness, so avoid driving or operating heavy machinery until you know how it affects you. It is not recommended for children as its safety and effectiveness have not been established. Elderly patients should use it with caution due to a potentially increased risk of bone fractures with long-term use. Avoid consuming alcohol, as it can worsen acidity and cause increased drowsiness. Consult your doctor if you experience unexplained weight loss, persistent stomach pain, indigestion, vomiting food or blood, or pass black stools.

What happens if a dose of Rablet IT Capsule is missed?

If you miss a dose of Rablet IT Capsule, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Rablet IT Capsule be stored?

Rablet IT Capsule should be stored in a cool, dry place, protected from direct sunlight, moisture, and heat. It should be kept out of sight and reach of children and pets. Typically, it should be stored at controlled room temperature, between 20°C to 25°C (68°F to 77°F) or below 30°C, and should not be frozen.