Tolperitas D Tablet

TOLPERITAS D TABLET is a combination medicine manufactured by Intas Pharmaceuticals Ltd., designed to alleviate pain and discomfort caused by muscle spasms.

• Name: Tolperitas D Tablet
• Composition: Each tablet typically contains Diclofenac (a Non-Steroidal Anti-inflammatory Drug - NSAID) and Tolperisone (a skeletal muscle relaxant). Diclofenac works by blocking pain and inflammation-causing chemicals, while Tolperisone relaxes muscles by acting on the central nervous system.
• Uses: It is prescribed for adults to manage painful muscle spasms, back pain (such as ankylosing spondylitis), joint pain and swelling (like osteoarthritis, rheumatoid arthritis), neck pain, sports injuries, and sprains.
• Dosage and Administration: Take TOLPERITAS D TABLET as directed by your physician, usually with or just after meals to prevent stomach upset. Swallow the tablet whole with a glass of water; do not crush or chew it. The exact dosage and duration will be determined by your doctor based on your condition.
• Side Effects: Common side effects include dizziness, headache, nausea, vomiting, indigestion, stomach pain, heartburn, flatulence, loss of appetite, increased liver enzymes, skin rashes, dry mouth, and sleepiness. Serious side effects may include severe allergic reactions, severe skin reactions, or gastrointestinal bleeding.
• Precautions:
  • Avoid use if pregnant (especially during the last trimester) or breastfeeding.
  • Contraindicated in patients with severe gastrointestinal bleeding, perforation, or ulcers.
  • Use with caution in patients with heart disease (due to increased risk of heart attack or stroke), liver, kidney, lung problems, diabetes, high blood cholesterol, asthma, or bleeding disorders.
  • Alcohol consumption should be avoided as it can increase drowsiness and the risk of stomach bleeding.
  • This medicine may cause dizziness or drowsiness; therefore, caution is advised when driving or operating machinery.
  • Inform your doctor about all other medications you are taking, as drug interactions can occur (e.g., with blood thinners, blood pressure medicines, other NSAIDs).
• Storage: Store TOLPERITAS D TABLET below 30°C in a cool, dry place, away from the reach of children and pets. Keep it in its original packaging.

TOLPERITAS D TABLET by INTAS PHARMACEUTICALS LTD is a combination medication containing Tolperisone and Diclofenac, primarily used to relieve pain and discomfort associated with muscle spasms.

What is Tolperitas D Tablet used for?

Tolperitas D Tablet is primarily used to reduce and relieve pain caused by sudden, involuntary muscle contractions known as muscle spasms. It is commonly prescribed for various conditions such as muscle stiffness, back pain (including ankylosing spondylitis), joint pain and swelling (like osteoarthritis and rheumatoid arthritis), neck pain, sports injuries, and sprains. This medicine helps relax skeletal muscles, improve mobility, and reduce stiffness.

How does Tolperitas D Tablet work?

Tolperitas D Tablet contains two active ingredients: Tolperisone and Diclofenac.

• Tolperisone is a skeletal muscle relaxant that acts directly on the spinal cord and central nervous system to relieve muscle stiffness or spasm and improve muscle movement. It is believed to work by blocking voltage-gated sodium and calcium channels, which reduces nerve impulses that trigger muscle contraction.
• Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and a painkiller. It works by inhibiting the synthesis of prostaglandins, which are chemicals in the body responsible for causing pain and inflammation. Together, these ingredients provide relief from acute muscle spasms and associated pain by relaxing muscles and reducing inflammation.

What is the usual dosage of Tolperitas D Tablet?

Tolperitas D Tablet should be taken as prescribed by your doctor. The usual dosage is often one tablet per day. It is important to swallow the tablet whole with a glass of water, usually with or after food, to minimize stomach upset. Do not chew, crush, or break the tablet. The exact dosage and duration of treatment will depend on your specific condition and response to treatment, as determined by your doctor.

What are the possible side effects of Tolperitas D Tablet?

Common side effects of Tolperitas D Tablet may include nausea, vomiting, indigestion, bloating, stomach pain, heartburn, dizziness, headache, dry mouth, sleepiness, muscle pain, muscle weakness, and increased liver enzymes. If these side effects persist or worsen, it is advisable to consult your doctor. More serious, though rare, side effects can include severe allergic reactions, signs of severe skin reactions, or gastrointestinal bleeding. Tolperitas D Tablet can also increase the risk of heart attack or stroke, especially with prolonged use.

Is Tolperitas D Tablet safe during pregnancy or breastfeeding?

Tolperitas D Tablet is generally not recommended during pregnancy, especially during the last three months, as insufficient information is available regarding its safety. It is essential to consult your doctor before using this medicine if you are pregnant or planning to become pregnant. For breastfeeding mothers, Tolperitas D Tablet is generally not recommended as a component of the medicine passes into breast milk and may harm the infant.

Can it be taken with other medications?

Tolperitas D Tablet can interact with various medications. It is crucial to inform your doctor about all medicines you are currently taking, including prescription, over-the-counter drugs, herbal remedies, and supplements. Key interactions to be aware of include:

• Anticoagulants/Antiplatelet agents: Such as warfarin, heparin, aspirin, and clopidogrel, as it can increase the risk of bleeding.
• Other NSAIDs: Taking other pain relievers like ibuprofen or naproxen concurrently can increase the risk of side effects, especially stomach problems.
• Medicines for high blood pressure: Tolperitas D Tablet might decrease the effectiveness of blood pressure-lowering medications like furosemide, enalapril, olmesartan, losartan, metoprolol, and nebivolol.
• Diuretics: Medicines that increase urine output, such as furosemide.
• Cardiac glycosides: Such as digoxin.
• Immunosuppressants: Like methotrexate, cyclosporine, and tacrolimus, as their effects can be increased, potentially causing kidney damage.

What precautions should be taken?

Several precautions should be observed while taking Tolperitas D Tablet:

• Alcohol: Avoid alcohol consumption as it can increase drowsiness, dizziness, and the risk of stomach bleeding.
• Driving and operating machinery: This medicine may cause dizziness, drowsiness, or blurred vision, so exercise caution when driving or operating heavy machinery until you know how it affects you.
• Pre-existing conditions: Inform your doctor if you have a history of stomach or intestinal ulcers, bleeding issues, severe kidney or liver disease, heart conditions (such as heart attack or stroke risk), blood disorders, asthma (especially NSAID-induced asthma), or allergies to any components of the tablet.
• Children: Tolperitas D Tablet is generally not recommended for children under 18 years of age as its safety and efficacy have not been established.
• Long-term use: Long-term use should be monitored by a doctor, especially if you have underlying health conditions like kidney or liver issues.

What happens if a dose is missed?

If you miss a dose of Tolperitas D Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should it be stored?

Store Tolperitas D Tablet in its original container, tightly closed, at a temperature below 30°C in a cool, dry place. Keep it out of the reach of children and pets, and dispose of any unused medicine properly.