Itralase Sb 130 Mg Capsule (10 Cap)

ITRALASE SB 130 MG CAPSULE (10 CAP) by CIPLA LTD.

Name

• Brand Name: Itralase SB 130 MG Capsule
• Common Name: Itraconazole Capsule

Composition

Itralase SB 130 MG Capsule contains Itraconazole 130 mg as its active ingredient. It belongs to the class of antifungal medications.

Uses

Itralase SB 130 MG Capsule is an antifungal medicine prescribed to manage a wide range of fungal and yeast infections throughout the body. It works by stopping the growth of fungi.

Specific conditions it is used for include:

• Skin Fungal Infections: Such as ringworm, athlete's foot, and jock itch.
• Nail Fungal Infections: Affecting fingernails and toenails, which can cause thickening, brittleness, or discoloration.
• Oral and Throat Infections: Including oral thrush and infections in the throat.
• Vaginal Yeast Infections: Such as vaginal thrush.
• Lung and Respiratory Infections: Prescribed for serious infections like aspergillosis and histoplasmosis.
• Systemic Fungal Infections: Infections that have spread to internal organs like the brain, heart, or urinary system. It is also used to treat cryptococcal infection and infections caused by Blastomyces.
• Prevention: Can be used to prevent fungal infections in immunocompromised patients.

Dosage and Administration

Itralase SB 130 MG Capsule should be taken exactly as prescribed by your doctor.

• It is generally recommended to take the capsule whole with food to improve absorption and prevent stomach upset.
• Do not crush or chew the capsule.
• Take the medicine at evenly spaced times and complete the full course of treatment, even if symptoms improve, to prevent the infection from returning or developing resistance.
• The dose and duration depend on the type and severity of the infection and your response to treatment.
• If a dose is missed, take it as soon as remembered, but skip it if it's almost time for the next dose. Do not take extra doses.

Side Effects

Common side effects may include:

• Headache
• Nausea
• Diarrhea
• Fatigue/Tiredness
• Cough, cold, throat pain
• Back pain
• Stomach pain/Abdominal discomfort
• Vomiting
• Dizziness

Serious side effects requiring immediate medical attention include:

• Liver damage, indicated by yellowing of eyes or skin (jaundice), dark urine, pale stools, severe stomach pain, loss of appetite, unusual tiredness, vomiting, or nausea.
• Severe allergic reactions such as severe skin rash, swelling of the face, lips, tongue, or throat, hives, or difficulty breathing.
• Symptoms of heart failure like shortness of breath, weight gain, or swelling.
• Irregular heartbeat.
• Tingling, numbness, weakness in limbs (neuropathy), or hearing loss.

Precautions

• Pregnancy: Itralase SB 130 MG Capsule is generally not recommended during pregnancy due to potential harm to the unborn baby. Consult your doctor for alternative options. A reliable method of contraception should be used to prevent pregnancy while taking this medicine.
• Breastfeeding: Use with caution or avoid, as the medicine may pass into breast milk and affect the infant.
• Liver/Kidney Problems: Caution is advised in patients with liver or kidney disease. Regular monitoring of liver function may be required, especially during prolonged treatment.
• Heart Conditions: Patients with a history of heart failure should avoid this medicine as it may cause severe adverse effects.
• Alcohol: Avoid consuming alcohol as it may increase the risk of liver damage.
• Drug Interactions:
  • Antacids and other medicines that decrease stomach acid (e.g., proton pump inhibitors, H2-receptor antagonists) can reduce the absorption of itraconazole, potentially decreasing its effectiveness. Do not take indigestion remedies within 2 hours of Itralase SB 130 MG Capsule.
  • Itraconazole can increase the levels and effects of anticoagulants (like warfarin), increasing the risk of bleeding.
  • Avoid concomitant use with antibiotics like rifampin, phenytoin, carbamazepine, and antiviral medicines like efavirenz as they may reduce the effect of Itralase SB 130 MG Capsule.
  • Antibiotics like ciprofloxacin, clarithromycin, and antiviral medicines like ritonavir may increase the effectiveness of this medicine.
• Driving and Operating Machinery: This medicine may cause dizziness or blurred vision. Avoid these activities if affected.
• Children and Older Patients: Caution is advised. Consult a doctor before giving to children under 18. Older patients may be more susceptible to side effects and should take it under medical supervision.

Storage

Store Itralase SB 130 MG Capsule at room temperature, not exceeding 30 degrees Celsius.

• Keep the packaging away from direct sunlight, moisture, and damp areas.
• Ensure the capsule container is tightly sealed when not in use.
• Keep this medicine out of reach of children and pets.
• Do not use the medicine after its expiry date.

What is Itralase SB 130 mg Capsule used for?

Itralase SB 130 mg Capsule is an antifungal medicine primarily used to treat various fungal and yeast infections throughout the body. These include infections of the mouth (oral thrush), throat, vagina, skin (such as ringworm, athlete's foot, jock itch), fingernails, toenails, and internal organs like the lungs (e.g., aspergillosis, histoplasmosis) and systemic fungal infections that can affect the brain or heart. It works by killing the fungi and preventing their growth, which helps alleviate symptoms and promotes healing.

How does Itralase SB 130 mg Capsule work?

Itralase SB 130 mg Capsule contains Itraconazole, which belongs to a class of antifungal medications called azole antifungals. It works by disrupting the production of ergosterol, a crucial component of the fungal cell membrane. By inhibiting ergosterol synthesis, the medicine weakens and damages the fungal cell membranes, causing essential cellular contents to leak out. This process effectively stops the growth of fungi and ultimately leads to their death, thereby clearing the infection.

What is the usual dosage for Itralase SB 130 mg Capsule?

The dosage and duration of Itralase SB 130 mg Capsule depend on the type and severity of the infection, as well as the patient's response to treatment. It should be taken exactly as prescribed by your doctor. Generally, the capsule should be swallowed whole with food to improve absorption, preferably at consistent intervals each day. It is crucial to complete the full course of treatment, even if symptoms improve, to prevent the infection from returning and to reduce the risk of developing resistant infections.

What are the possible side effects of Itralase SB 130 mg Capsule?

Common side effects may include nausea, headache, dizziness, vomiting, diarrhea, abdominal discomfort, constipation, cough, cold, and back pain. More serious side effects, which require immediate medical attention, include severe allergic reactions (e.g., severe skin rash, difficulty breathing, facial swelling), tingling or numbness in limbs, severe skin disorders with fever, liver problems (e.g., jaundice, dark urine, pale stools, stomach pain, loss of appetite), and symptoms of heart failure (e.g., shortness of breath, unexpected weight gain, swollen legs or stomach).

Is Itralase SB 130 mg Capsule safe during pregnancy or breastfeeding?

Itralase SB 130 mg Capsule is generally not recommended during pregnancy, as it may pose a risk of fetal harm, including severe birth defects, particularly at high doses. If you are pregnant or planning a pregnancy, it is advised to consult your doctor, who will weigh the benefits against potential risks. It is also probably unsafe to use during breastfeeding, as the medicine can pass into breast milk and may harm the baby. Always discuss with your doctor if you are breastfeeding.

Can Itralase SB 130 mg Capsule be taken with other medications?

Itralase SB 130 mg Capsule can interact with several other medications, which may affect its effectiveness or increase the risk of side effects.

• Antacids and acid-reducing medicines (like proton pump inhibitors or H2-receptor antagonists) can reduce the absorption of itraconazole, making it less effective. It's generally advised to avoid taking antacids within 2 hours of taking Itralase SB 130 mg Capsule, or to take the capsule with cola if you are using acid suppressors.
• Anticoagulants such as warfarin can have their effects increased by itraconazole, raising the risk of bleeding.
• Certain anticonvulsants (e.g., phenytoin, carbamazepine, phenobarbital) can decrease itraconazole levels, reducing its antifungal efficacy.
• Other medications like some antibiotics (e.g., rifampicin, isoniazid), antiviral medicines (e.g., efavirenz), and herbal supplements (e.g., St. John's Wort) can also interact. Always inform your doctor about all medications and herbal supplements you are currently taking.

What precautions should be taken when using Itralase SB 130 mg Capsule?

Before taking Itralase SB 130 mg Capsule, inform your doctor if you have a history of liver problems (e.g., jaundice), kidney issues, heart failure, a compromised immune system (including HIV/AIDS), or abnormal electrolyte levels. Regular liver function tests may be required for prolonged treatment durations exceeding one month. If you develop symptoms like yellowing of eyes or skin, dark urine, or stomach pain, contact your doctor immediately as these could indicate liver issues. Use a reliable method of contraception to prevent pregnancy during treatment. This medicine may cause dizziness, blurred vision, or hearing loss, so exercise caution when driving or operating machinery.

What happens if a dose of Itralase SB 130 mg Capsule is missed?

If you miss a dose of Itralase SB 130 mg Capsule, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this increases the risk of side effects.

How should Itralase SB 130 mg Capsule be stored?

Itralase SB 130 mg Capsule should be stored at room temperature, not exceeding 30 degrees Celsius. Keep the packaging away from direct sunlight, moisture, and damp areas. Ensure the capsule container is tightly sealed when not in use. Always keep this medicine out of the reach of children and pets, and do not use it after its expiry date.