Rablet D 40 (10 Cap )

RABLET D 40 Capsule

RABLET D 40 Capsule is a medication manufactured by Lupin Ltd. It is a combination medicine used to manage conditions related to excessive stomach acid production.

• Name:
  • Brand Name: Rablet D 40 Capsule (often referred to as Rablet D 40 SR Capsule)
• Composition:
  • Contains two active ingredients: Rabeprazole (40mg) and Domperidone (30mg).
  • Rabeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production.
  • Domperidone is a prokinetic agent that enhances the movement of the stomach and intestines, facilitating gastric emptying and reducing nausea and vomiting.
• Uses:
  • Primarily prescribed for Gastroesophageal Reflux Disease (GERD), also known as acid reflux, which causes heartburn, stomach pain, and irritation due to stomach acid flowing back into the food pipe.
  • Treatment of peptic ulcers (stomach and duodenal ulcers), including those caused by H. pylori infection or NSAID use.
  • Manages Zollinger-Ellison syndrome, a condition of overproduction of acid due to a pancreatic tumor.
  • Alleviates symptoms like nausea, vomiting, stomach discomfort, and bloating.
• Dosage and Administration:
  • Typically taken orally 30 minutes to one hour before a meal, preferably in the morning.
  • Swallow the capsule whole with water; do not crush, chew, or break it.
  • The exact dosage and duration are determined by a doctor based on the patient's condition and response to treatment.
• Side Effects:
  • Common: Headache, diarrhea, nausea, abdominal pain, vomiting, dizziness, flatulence, dry mouth, and joint pain.
  • Serious (rare): Severe allergic reactions, symptoms of liver problems, severe skin reactions, seizures, involuntary movements, and heart rhythm disorders. Prolonged use may lead to deficiencies in Vitamin B12 and magnesium, and an increased risk of bone fractures.
• Precautions:
  • Inform your doctor if you have liver or kidney disease, heart problems, gastric cancer, low magnesium/vitamin B12 levels, osteoporosis, or a pituitary gland tumor.
  • Not recommended for children under 16-18 years of age due to lack of safety data.
  • Use with caution in elderly patients.
  • Pregnant or breastfeeding women should consult their doctor before use, as it may be unsafe.
  • Avoid alcohol and smoking as they can worsen symptoms.
  • May cause dizziness or drowsiness; avoid driving or operating machinery if affected.
  • It may interact with blood thinners, antifungals, anti-HIV drugs, and iron supplements.
• Storage:
  • Store in a cool, dry place, away from direct sunlight and moisture, at a temperature below 25°C or 30°C.
  • Keep out of reach of children and pets.

What is Rablet D 40 used for?

Rablet D 40 Capsule is a combination medicine primarily used to treat gastroesophageal reflux disease (GERD), also known as acid reflux. It helps alleviate symptoms such as heartburn, stomach pain, and irritation caused by excessive stomach acid. It is also used to manage peptic ulcers (stomach and duodenal ulcers) and Zollinger-Ellison syndrome (a condition where the stomach produces too much acid due to a pancreatic tumor).

How does Rablet D 40 work?

Rablet D 40 contains two active ingredients: Rabeprazole and Domperidone. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme in the stomach wall (H+/K+ ATPase, or gastric proton pump) responsible for producing stomach acid, thereby reducing the amount of acid secreted. Domperidone is a dopamine receptor antagonist that increases the movement and contractions of the upper gastrointestinal tract, which helps food move more easily through the stomach and prevents acid from flowing back into the food pipe. It also blocks the vomiting-inducing center (chemoreceptor trigger zone - CTZ).

What is the usual dosage of Rablet D 40?

Rablet D 40 Capsule should be taken orally as prescribed by your doctor. It is typically recommended to take one capsule before the first meal of the day, preferably on an empty stomach, about 30 minutes to one hour before food. The capsule should be swallowed whole with water and not crushed, chewed, or broken. Your doctor will determine the appropriate dosage and duration of treatment based on your medical condition and response to the medication.

What are the possible side effects of Rablet D 40?

Common side effects of Rablet D 40 may include headache, diarrhea, nausea, abdominal pain, vomiting, dizziness, flatulence, and joint pain. Other reported side effects can include dry mouth, constipation, flu-like symptoms, nasal congestion, back pain, weakness, and sleepiness. These side effects are usually temporary and may resolve over time. However, if any of these symptoms worsen or persist, it is advisable to consult your doctor.

Is Rablet D 40 safe during pregnancy or breastfeeding?

The use of Rablet D 40 Capsule during pregnancy is generally not recommended as there is limited data on its safety, although some sources state it is safe. It is advised to consult your doctor if you are pregnant or planning to become pregnant. Domperidone, one of the components, passes into breast milk in small amounts and might affect the baby, making it generally not recommended during breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing it during pregnancy or breastfeeding.

Can Rablet D 40 be taken with other medications?

Rablet D 40 may interact with certain medications. It is important to inform your doctor about all the medicines, supplements, and herbal products you are currently taking to prevent possible interactions. It may interact with blood thinners (like warfarin), antifungals (like ketoconazole, itraconazole), anti-HIV drugs (like atazanavir, nelfinavir), anti-cancer medications, and certain antibiotics (like erythromycin, clarithromycin). Medicines used to treat heart failure, like digoxin, should be used cautiously.

What precautions should be taken with Rablet D 40?

Avoid taking Rablet D 40 if you are allergic to rabeprazole, domperidone, or any of its ingredients. Inform your doctor if you have a history of liver or kidney disease, heart problems, stomach or intestinal cancer, low magnesium levels, or low vitamin B12 levels. Prolonged use may lead to deficiencies in Vitamin B12, calcium, and magnesium, and an increased risk of bone fractures. It is not recommended for children below 12 or 16 years of age, depending on the source. Avoid alcohol consumption as it can worsen symptoms and may intensify drowsiness. This medicine may cause dizziness or drowsiness, so avoid driving or operating heavy machinery until you know how it affects you.

What happens if a dose of Rablet D 40 is missed?

If you miss a dose of Rablet D 40, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can lead to an overdose.

How should Rablet D 40 be stored?

Rablet D 40 Capsules should be stored in a cool and dry place, away from direct sunlight and moisture. Keep the medicine out of reach of children and pets. Ensure the medicine is used before its expiry date.