Derinide 100 Inh

DERINIDE 100 INH

DERINIDE 100 INH is a metered-dose inhaler manufactured by Zydus Healthcare Limited.

• Name: DERINIDE 100 INH (Common and Brand Name). Also known as DERinide 100 Inhaler CFC Free or DERINIDE 100MCG INHALER.
• Composition: The active ingredient is Budesonide, a corticosteroid, at a strength of 100 mcg per metered dose.
• Uses: DERINIDE 100 INH is primarily used for the long-term maintenance treatment of asthma to prevent symptoms like wheezing and shortness of breath. It helps reduce inflammation and irritation in the airways, making breathing easier. It is also used in the management of Chronic Obstructive Pulmonary Disease (COPD) and for treating a specific type of cough in children. This medication is a "preventer" and will not provide immediate relief during an ongoing asthma attack.
• Dosage and Administration: DERINIDE 100 INH should be used regularly at the same time each day, as prescribed by your doctor. It is important to use the lowest effective dose. The full benefits may take several weeks to manifest, and consistent use is crucial, even when symptoms are absent. After each inhalation, gargle with warm water to help prevent fungal infections in the mouth and throat.
• Side Effects:
  • Common: Throat irritation, difficulty swallowing, oral fungal infections (thrush), headache, indigestion, abdominal pain, nausea, and hoarseness in voice.
  • Serious (less common): Increased risk of infections, muscle pain or weakness, irritability, depression, joint pain, osteoporosis (with long-term high doses), and eye damage (glaucoma or cataracts) with prolonged use.
• Precautions: Inform your doctor if you have tuberculosis, oral or lung infections, liver disease, high blood pressure, diabetes, or osteoporosis. Long-term use may require monitoring of bone density and eye pressure. Avoid close contact with individuals suffering from colds or flu due to an increased risk of infection. Consult your doctor if pregnant or breastfeeding. Grapefruit and grapefruit juice should be avoided as they can increase budesonide levels.
• Storage: Store below 30°C, in a cool and dry place, away from direct sunlight. Some sources advise storing in a refrigerator (2-8°C) but emphasize not to freeze the medication. Keep out of sight and reach of children.

DERINIDE 100 INH, manufactured by ZYDUS HEALTHCARE LIMITED, is a corticosteroid inhaler primarily used for the long-term management and prevention of asthma symptoms. It contains Budesonide, which helps reduce inflammation in the airways, making breathing easier.

What is DERINIDE 100 INH used for?

DERINIDE 100 INH is used to prevent the symptoms of asthma, such as wheezing, shortness of breath, chest tightness, and coughing. It is a "preventer" medication, meaning it helps to control asthma symptoms over time and prevent flare-ups, but it will not provide immediate relief during an ongoing asthma attack. For sudden asthma attacks, a fast-acting "reliever" inhaler should be used.

How does DERINIDE 100 INH work?

DERINIDE 100 INH contains budesonide, a steroid that works by reducing inflammation and swelling in the airways. It prevents cells in the lungs and breathing passages from releasing chemical messengers that cause this inflammation, thereby making breathing easier and improving lung function.

What is the usual dosage?

Your doctor will determine the appropriate dose and duration for you, as it varies based on your medical condition. It's important to take the lowest effective dose needed to control your asthma. For the inhaler form, a single maximum dose of 360 mcg, taken twice daily, has been mentioned. The full benefits of the medication may take several weeks to be realized, so consistent and regular use is crucial, even if you feel symptom-free.

What are the possible side effects?

Common side effects of DERINIDE 100 INH include throat irritation, difficulty swallowing, headache, indigestion, and an increased risk of fungal infections in the mouth or throat (oral thrush). Other reported side effects include muscle pain, muscle weakness, irritability, abdominal pain, depression, and joint pain. Serious but rare side effects can occur, and any concerns should be discussed with your doctor. Rinsing your mouth and throat with water or brushing your teeth after each use can help reduce throat irritation and prevent fungal infections.

Is it safe during pregnancy or breastfeeding?

DERINIDE 100 INH may be unsafe to use during pregnancy, as animal studies have shown harmful effects on the developing baby. However, the inhaler form is generally considered safer during pregnancy compared to the oral form, but it is still recommended to consult your doctor to weigh the benefits and risks. Regarding breastfeeding, DERINIDE 100 INH is probably unsafe to use during breastfeeding, although limited data suggests no significant risk to the baby as only minuscule amounts pass into breast milk. Always consult your doctor if you are pregnant or breastfeeding.

Can it be taken with other medications?

DERINIDE 100 INH may interact with certain medications. For instance, concomitant use with antifungal medicines like Ketoconazole and Itraconazole, or anti-HIV medicines such as Nelfinavir, Ritonavir, and Indinavir, may increase the concentration of DERINIDE 100 INH in the body, leading to increased side effects. Other steroids and certain asthma management medications should also be used cautiously. Always inform your doctor about all medications you are currently taking to avoid potential interactions.

What precautions should be taken?

Before using DERINIDE 100 INH, inform your doctor if you have tuberculosis, any infections in your mouth or lungs, or liver disease. Long-term use may increase the risk of infections, so avoid contact with people who have colds or the flu. Prolonged use might also lead to weakened bones (osteoporosis) and eye damage (glaucoma or cataracts), necessitating regular monitoring and potential additional tests for bone density and eye pressure. It is not recommended for children under 6 years of age, and should be used with caution in elderly patients. Avoid consuming large amounts of grapefruit or grapefruit juice as it can increase budesonide levels.

What happens if a dose is missed?

If you forget a dose of DERINIDE 100 INH, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one, as this may increase the chances of developing side effects.

How should it be stored?

Store DERINIDE 100 INH in a cool and dry place, away from direct sunlight and extreme temperatures, ideally below 30°C or between 10ºC to 25ºC. Keep it in its original packing, tightly closed to protect it from moisture, and out of the sight and reach of children and pets.