Dapanova 10 Tablet (15 Tab)

DAPANOVA 10 TABLET

DAPANOVA 10 TABLET, manufactured by MEDLEY PHARMACEUTICALS LTD., is a prescription medication primarily used in the management of type 2 diabetes mellitus. It belongs to a class of medicines known as sodium-glucose co-transporter 2 (SGLT2) inhibitors.

• Name:

  • Common Name: Dapagliflozin (10 mg)
  • Brand Name: DAPANOVA 10 TABLET

• Composition:

  • Each tablet contains 10 mg of Dapagliflozin.

• Uses:

  • Type 2 Diabetes Mellitus: It is used to lower high blood sugar levels by removing excess glucose from the body through urine, often in conjunction with diet and exercise. It can be used alone or in combination with other antidiabetic medications like metformin or insulin.
  • Heart Failure: DAPANOVA 10 TABLET is also prescribed for the management of heart failure in adults, helping to reduce the risk of hospitalization.
  • Chronic Kidney Disease (CKD): It is used to slow the progression of chronic kidney disease in adults, including those with type 2 diabetes.
  • Weight Loss: It may contribute to moderate weight loss by promoting caloric loss.

• Dosage and Administration:

  • The standard adult dose is typically 10 mg once daily, taken orally with or without food.
  • It should be swallowed whole with a glass of water and taken at the same time each day.
  • Dosage may be adjusted by a doctor, especially in elderly patients or those with reduced kidney or liver function.
  • Not recommended for children under 10 years of age.

• Side Effects:

  • Common Side Effects: Genital fungal infections (thrush), urinary tract infections (UTIs), increased urination frequency, back pain, dizziness, rash, dehydration, thirst, constipation, and dry mouth.
  • Serious Side Effects (Seek medical attention immediately): Signs of allergic reaction (skin rash, swelling of face/throat), diabetic ketoacidosis (nausea, vomiting, stomach pain, confusion, sweet-smelling breath), or acute kidney injury.

• Precautions:

  • Kidney and Liver Problems: Inform your doctor if you have kidney or liver issues, as dose adjustments or careful monitoring may be required. It is not recommended for severe kidney disease or patients on dialysis.
  • Dehydration: Maintain adequate fluid intake to prevent dehydration, especially if experiencing excessive vomiting or diarrhea.
  • Infections: Practice good genital hygiene to minimize the risk of fungal and urinary tract infections.
  • Pregnancy and Breastfeeding: Not advised during pregnancy (especially second and third trimesters) or breastfeeding due to limited safety data.
  • Alcohol: Avoid excessive alcohol consumption as it can increase the risk of low blood sugar (hypoglycemia) and diabetic ketoacidosis.
  • Other Medications: Inform your doctor about all other medications you are taking, especially diuretics and insulin or insulin secretagogues, to avoid potential interactions and increased risk of hypoglycemia.
  • Monitoring: Regular monitoring of blood sugar, kidney function, and hydration status is advised.

• Storage:

  • Store below 30°C.
  • Keep away from sunlight and moisture.
  • Keep out of sight and reach of children.

DAPANOVA 10 TABLET (containing Dapagliflozin 10 mg) is a medication primarily used for managing Type 2 Diabetes Mellitus. It also plays a significant role in the management of heart failure and chronic kidney disease in adults. Below are frequently asked questions regarding this medication.

What is DAPANOVA 10 TABLET used for?

DAPANOVA 10 TABLET is prescribed to manage Type 2 Diabetes Mellitus, helping to control high blood sugar levels when diet and exercise alone are insufficient. It is also used in adults to treat heart failure and chronic kidney disease (CKD), reducing the risk of hospitalization for heart failure and slowing the progression of kidney disease.

How does DAPANOVA 10 TABLET work?

This medication contains Dapagliflozin, which belongs to a class of drugs called SGLT2 inhibitors. It works by blocking the sodium-glucose co-transporter 2 (SGLT2) protein in the kidneys. This action prevents glucose from being reabsorbed into the bloodstream, causing excess sugar, sodium, and water to be flushed out of the body through urine. This process effectively lowers blood sugar levels, can lead to moderate weight loss, and also helps protect the heart and kidneys.

What is the usual dosage of DAPANOVA 10 TABLET?

For adults and elderly patients, the typical dose is 10 mg taken once daily. It can be taken with or without food, but it is advisable to take it at approximately the same time each day. For elderly patients or those with reduced kidney function, a lower starting dose (e.g., 5 mg daily) and close monitoring may be recommended by a doctor.

What are the possible side effects of DAPANOVA 10 TABLET?

Common side effects include genital fungal infections (like thrush), urinary tract infections (UTIs), increased urination (polyuria), back pain, dizziness, rash, dehydration, thirst, constipation, dry mouth, nausea, vomiting, dyslipidemia, nasopharyngitis (inflammation of the throat and nasal passages), and sore throat. It's important to contact your physician if any of these side effects worsen or persist. Serious, though rare, side effects can include ketoacidosis or acute kidney injury.

Is DAPANOVA 10 TABLET safe during pregnancy or breastfeeding?

DAPANOVA 10 TABLET is generally not recommended during pregnancy, especially in the second and third trimesters, due to potential risks to the developing fetus. It is unknown if the medication or its components pass into human breast milk, so it is advised to consult your doctor to discuss potential risks and benefits if you are breastfeeding.

Can DAPANOVA 10 TABLET be taken with other medications?

DAPANOVA 10 TABLET can be taken alone or in combination with other diabetes medications. However, when taken with insulin or insulin secretagogues (like sulfonylureas), it may increase the risk of low blood sugar (hypoglycemia), and a lower dose of those medications might be necessary. It may also interact with diuretics (water pills), potentially increasing the risk of dehydration and low blood pressure. Always inform your doctor about all medications you are currently taking to avoid potential interactions.

What precautions should be taken while taking DAPANOVA 10 TABLET?

Before taking DAPANOVA 10 TABLET, inform your doctor if you have any liver or kidney problems, severe low blood pressure, or are severely dehydrated. It is not recommended for patients with severe kidney impairment or those on dialysis. Maintain good genital hygiene and ensure adequate fluid intake to prevent infections and dehydration. Avoid excessive alcohol consumption, as it can increase the risk of low blood sugar and diabetic ketoacidosis. Regular monitoring of blood sugar, kidney function, and hydration status is advised.

What happens if a dose of DAPANOVA 10 TABLET is missed?

If you miss a dose of DAPANOVA 10 TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one, as this may lead to low blood sugar or dehydration.

How should DAPANOVA 10 TABLET be stored?

DAPANOVA 10 TABLET should be stored in a cool and dry place, preferably below 30°C. Keep it away from direct sunlight and moisture. Ensure that the medicine is kept out of sight and reach of children.