Xenia M 12.5/1000mg Er Tab

XENIA M 12.5/1000MG ER TAB

• Name: XENIA M 12.5/1000MG ER TAB

• Brand Name: Xenia M

• Composition:

  • Empagliflozin: 12.5 mg
  • Metformin Hydrochloride: 1000 mg (Extended Release)

• Uses: Xenia M 12.5/1000MG ER TAB is primarily used for the treatment of Type 2 Diabetes Mellitus in adults. It helps to control high blood sugar levels when used in conjunction with a proper diet and exercise regimen. This medication aids in improving glycemic control and preventing serious diabetes-related complications such as kidney damage, eye damage, nerve problems, and cardiovascular disease.

• Dosage and Administration:

  • Take Xenia M exactly as prescribed by your doctor, usually with meals, at the same time each day.
  • Swallow the tablet whole with water; do not chew, crush, or break it.
  • Do not discontinue the medicine without consulting your doctor, as this can lead to an increase in blood glucose levels.
  • If a dose is missed, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue your regular schedule. Do not take a double dose to compensate.

• Side Effects:

  • Common: Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, urinary tract infections, female genital yeast infections, taste changes, joint pain, nasopharyngitis, and hypoglycemia (low blood sugar). Dehydration and increased urination may also occur.
  • Serious: Lactic acidosis (rare but serious complication associated with metformin).

• Precautions:

  • Contraindications: Do not use if allergic to empagliflozin, metformin, or any other ingredients. It is contraindicated in conditions like metabolic acidosis (e.g., lactic acidosis, diabetic ketoacidosis), diabetic pre-coma, kidney failure, severe liver problems, and conditions that may affect kidney function (e.g., severe infection, dehydration, shock).
  • Pregnancy and Breastfeeding: Not recommended for use during pregnancy or while breastfeeding.
  • Alcohol: Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis and impact blood sugar control.
  • Kidney/Liver Impairment: Use with caution. Regular monitoring of kidney function is advisable, especially in elderly patients, and it is generally avoided in patients with kidney disease.
  • Drug Interactions: Inform your doctor about all medicines, supplements, or herbal products you are currently taking, as Xenia M can interact with diuretics, insulin, sulfonylureas, lithium, and other medications.
  • Driving: May affect your ability to drive if blood sugar levels are too low or too high, or if it causes dizziness or sleepiness.
  • Hypoglycemia: The risk of low blood sugar is higher when used with other antidiabetic medicines. Always carry sugary food or fruit juice in case of hypoglycemia symptoms.

• Storage:

  • Store in a cool and dry place, away from direct sunlight.

Here are frequently asked questions regarding XENIA M 12.5/1000MG ER TAB:

What is XENIA M 12.5/1000MG ER TAB used for?

XENIA M 12.5/1000MG ER TAB is a combination medication containing Empagliflozin and Metformin Hydrochloride Extended Release. It is primarily used with diet and exercise to manage high blood sugar levels in adults with Type 2 Diabetes Mellitus. Additionally, it is indicated to reduce the risk of cardiovascular death in adults with Type 2 Diabetes and established cardiovascular disease, and to lower the risk of worsening kidney disease, end-stage kidney disease, and hospitalization in patients with chronic kidney disease (CKD).

How does XENIA M 12.5/1000MG ER TAB work?

This medicine combines two active ingredients with different mechanisms of action:

• Empagliflozin: This is a sodium-glucose co-transporter-2 (SGLT2) inhibitor. It works in the kidneys by preventing the reabsorption of glucose (blood sugar), leading to increased glucose excretion in the urine, thereby lowering blood sugar levels.
• Metformin Hydrochloride (Extended Release): This belongs to the biguanide class of antidiabetic agents. It reduces the amount of glucose produced by the liver, decreases the absorption of sugar from the stomach, and improves the body's sensitivity to insulin, helping it use sugar more effectively.

What is the usual dosage for XENIA M 12.5/1000MG ER TAB?

For adults, the typical starting dose for extended-release tablets is usually one or two tablets once a day, taken with food in the morning. Your doctor may adjust the dose as needed and tolerated, but the total daily dose should generally not exceed 25 mg of empagliflozin and 2000 mg of metformin. The tablets should be swallowed whole and not cut, crushed, dissolved, or chewed.

What are the possible side effects of XENIA M 12.5/1000MG ER TAB?

Common side effects may include urinary tract infections (UTIs), genital yeast infections (more common in women), increased urination, headache, diarrhea, nausea, vomiting, gas, and abdominal discomfort.

Serious side effects that require immediate medical attention include:

• Lactic Acidosis: A rare but serious complication, primarily associated with metformin, characterized by muscle pain or cramps, stomach pain, trouble breathing, general discomfort, and unusual sleepiness or weakness.
• Diabetic Ketoacidosis (DKA): Symptoms may include increased thirst, dry mouth, fruity breath odor, stomach pain, nausea, and vomiting.
• Dehydration: Symptoms like increased thirst, dry mouth, feeling lightheaded, headache, and dark urine.
• Hypoglycemia (low blood sugar): Especially when used with other diabetes medications like insulin or sulfonylureas. Symptoms include dizziness, sweating, shaking, fast heartbeat, hunger, confusion, and blurred vision.
• Kidney problems: Changes in urination, bloody urine, or significant weight gain.
• Fournier's gangrene: A rare but severe infection around the genitals or rectum.
• Lower limb amputations: New pain, tenderness, sores, or infections in the legs or feet.

Is XENIA M 12.5/1000MG ER TAB safe during pregnancy or breastfeeding?

XENIA M 12.5/1000MG ER TAB is generally not recommended during pregnancy, especially during the second and third trimesters, as it could harm an unborn baby. For women of childbearing potential, birth control options should be discussed with a doctor, as this medicine may cause ovulation. It is also not usually recommended during breastfeeding because it is unknown how much passes into breast milk and its potential effects on the infant.

Can XENIA M 12.5/1000MG ER TAB be taken with other medications?

Yes, but caution is advised as certain medications can interact with XENIA M 12.5/1000MG ER TAB. It's crucial to inform your doctor about all other medications, vitamins, and herbal products you are taking. Significant interactions can occur with:

• Diuretics (water pills): May increase the risk of dehydration and low blood pressure.
• Insulin or insulin secretagogues (e.g., sulfonylureas): May increase the risk of hypoglycemia (low blood sugar), potentially requiring a dose reduction of insulin or sulfonylurea.
• Iodinated contrast agents: Metformin should be temporarily discontinued before or at the time of imaging procedures involving iodinated contrast, especially in patients with certain kidney or liver conditions, and restarted after assessing renal function.
• Alcohol: Excessive alcohol intake should be avoided as it can increase the risk of lactic acidosis.
• Certain antibiotics, blood pressure medications, and others: These can affect blood sugar levels or interfere with metformin clearance.

What precautions should be taken while using XENIA M 12.5/1000MG ER TAB?

• Renal function: Your doctor should assess your kidney function before starting and periodically during treatment, as impaired renal function can affect the medicine's efficacy and increase the risk of lactic acidosis. The medication is contraindicated in severe kidney impairment.
• Liver disease: Avoid use if you have severe liver problems or a history of alcohol abuse.
• Dehydration: Stay well-hydrated, especially during illness (fever, vomiting, severe diarrhea) or strenuous exercise, as dehydration can lead to kidney problems and other serious side effects.
• Surgery or medical procedures: You may need to stop taking this medicine for a period before major surgery, procedures requiring fasting, or diagnostic tests involving contrast dyes.
• Type 1 Diabetes: This medication is not for people with Type 1 Diabetes or diabetic ketoacidosis.
• Vitamin B12 levels: Metformin can lower vitamin B12 levels; your doctor may monitor these.

What happens if a dose of XENIA M 12.5/1000MG ER TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should XENIA M 12.5/1000MG ER TAB be stored?

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep it out of the reach of children. Do not keep outdated medicine or medicine no longer needed.