Dapaglyn 10 Mg Tablet (10 Tab)

DAPAGLYN 10 MG TABLET

DAPAGLYN 10 MG TABLET is a medication manufactured by Zydus Healthcare Limited.

• Name:
  • Brand Name: Dapaglyn 10 mg Tablet
  • Common Name: Dapagliflozin
• Composition:
  • Active Ingredient: Dapagliflozin 10 mg
  • Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor.
• Uses: Dapaglyn 10 mg Tablet is primarily used to manage and treat type 2 diabetes mellitus in adults, and children aged 10 years or older, when diet and exercise alone are insufficient to control blood glucose levels. It is also prescribed for:
  • Reducing the risk of hospitalization for heart failure in adults with type 2 diabetes and established cardiovascular disease or multiple risk factors.
  • Treating chronic kidney disease in adults with reduced kidney function, helping to protect kidneys from losing function. The medication works by helping the kidneys remove excess sugar from the body through urine, thereby lowering blood sugar levels. It can also help reduce blood pressure and fluid overload.
• Dosage and Administration:
  • The typical recommended dose for adults is 10 mg once daily.
  • It can be taken with or without food, preferably at the same time each day.
  • Swallow the tablet whole with water; do not crush, chew, or break it.
  • Do not exceed the prescribed dosage without consulting a doctor.
  • If a dose is missed within 12 hours of the usual time, take it as soon as remembered. If more than 12 hours have passed, skip the missed dose and resume the regular schedule. Do not double the next dose.
• Side Effects: Common side effects may include:
  • Genital fungal infections (vaginal yeast infections, yeast infections of the penis)
  • Urinary tract infections (UTIs)
  • Nasopharyngitis (inflammation of the throat and nasal passages, leading to stuffy or runny nose, sore throat)
  • Increased urination (polyuria)
  • Nausea, or rarely, vomiting
  • Dizziness
  • Hypoglycemia (low blood sugar), especially when taken with other antidiabetic medicines, alcohol, or if meals are missed. Symptoms include shivering, sweating, hunger, pounding heart, and dizziness.
  • Low blood pressure (hypotension)
  • Dehydration
  • Rash
• Precautions:
  • Inform your doctor if you have kidney or liver issues, or a history of urinary tract infections, as dosage adjustments or caution may be required.
  • Not recommended for treating type 1 diabetes or diabetic ketoacidosis.
  • Caution is advised in pregnant or breastfeeding women; consult a doctor before use.
  • Avoid excessive alcohol consumption as it may increase the risk of adverse effects like low blood sugar and dehydration.
  • Monitor blood sugar levels regularly.
  • May interact with diuretics, potentially increasing the risk of dehydration. Interactions with insulin or sulfonylureas may heighten the risk of hypoglycemia.
  • Not recommended for children under 10 years of age.
  • Patients with severe kidney disease or on dialysis should avoid this medicine.
• Storage:
  • Store below 30°C in a cool, dry place, away from excessive heat, moisture, and direct sunlight.
  • Keep in original packaging (blister pack/bottle).
  • Keep out of sight and reach of children.
  • Dispose of expired or unused tablets safely.

Here are some frequently asked questions about DAPAGLYN 10 MG TABLET (Dapagliflozin) by ZYDUS HEALTHCARE LIMITED:

What is DAPAGLYN 10 MG TABLET used for?

DAPAGLYN 10 MG TABLET, containing dapagliflozin, is primarily used to manage type 2 diabetes mellitus by helping to control high blood sugar levels. It is also prescribed to reduce the risk of hospitalization for heart failure in adults with type 2 diabetes and established cardiovascular disease or multiple cardiovascular risk factors. Additionally, it helps to reduce the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure with reduced ejection fraction, and to reduce the risk of worsening kidney disease, end-stage kidney disease, cardiovascular death, and hospitalization for heart failure in patients with chronic kidney disease.

How does DAPAGLYN 10 MG TABLET work?

Dapagliflozin belongs to a class of medicines called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It works by blocking the reabsorption of glucose (sugar) in the kidneys, causing excess glucose to be removed from the body through urine. This process helps to lower blood sugar levels. The medicine also reduces sodium reabsorption, which can decrease the workload on the heart and lower pressure within the kidney's filtering units.

What is the usual dosage for DAPAGLYN 10 MG TABLET?

For type 2 diabetes in adults and children aged 10 years and older, the typical starting dose is 5 mg once daily, which can be increased to 10 mg once daily if more glycemic control is needed. For heart failure and chronic kidney disease in adults, the usual recommended dose is 10 mg once daily. DAPAGLYN 10 MG TABLET should be taken orally once a day, with or without food, ideally at the same time each day.

What are the possible side effects of DAPAGLYN 10 MG TABLET?

Common side effects include vaginal yeast infections in women and yeast infections of the penis in men, stuffy or runny nose, sore throat, and increased or urgent urination, sometimes at night. More serious side effects can include dehydration (leading to dizziness or faintness), diabetic ketoacidosis (high ketones and acid in the blood), and severe urinary tract infections. Low blood sugar (hypoglycemia) can also occur, particularly if taken with other diabetes medications like insulin or sulfonylureas. A rare but serious bacterial infection in the genital area, known as Fournier's gangrene, has also been reported.

Is DAPAGLYN 10 MG TABLET safe during pregnancy or breastfeeding?

Dapagliflozin is generally not recommended during pregnancy, especially during the second and third trimesters. Animal studies have indicated potential risks to fetal kidney development. If you become pregnant, consult your doctor immediately, as they may switch you to an alternative medication. Similarly, it is not usually recommended during breastfeeding. It is unknown if the medicine passes into breast milk, but there is a theoretical risk of harm to a nursing infant's developing kidneys. Your doctor can discuss safe feeding options for your baby.

Can DAPAGLYN 10 MG TABLET be taken with other medications?

Yes, DAPAGLYN 10 MG TABLET can be taken alongside other antidiabetic medications, including insulin and sulfonylureas. However, if taken with insulin or insulin secretagogues, your doctor may need to adjust the doses of those medications to minimize the risk of low blood sugar. It's important to inform your doctor about all prescription, over-the-counter, and herbal medications you are taking, as dapagliflozin can interact with various drugs, including certain diuretics and blood pressure medications.

What precautions should be taken while on DAPAGLYN 10 MG TABLET?

Before starting treatment, your doctor should assess your fluid status, and you should maintain adequate fluid intake to prevent dehydration, especially during exercise, hot weather, or illness. It is not intended for individuals with type 1 diabetes or for treating diabetic ketoacidosis. Inform your doctor if you have kidney or liver problems, a history of urinary tract infections, low blood pressure, or if you regularly consume alcohol. You may need to temporarily stop taking this medicine at least 3 days before any scheduled surgery.

What happens if a dose of DAPAGLYN 10 MG TABLET is missed?

If you miss a dose of DAPAGLYN 10 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for a missed one.

How should DAPAGLYN 10 MG TABLET be stored?

DAPAGLYN 10 MG TABLET should be stored in a closed container at room temperature, typically between 20°C to 25°C (68°F to 77°F), away from excessive heat, moisture, and direct light. Keep it out of the reach of children. Do not use any outdated or no longer needed medicine.