Ketoflam P Tab

Ketoflam-P Tablet

Ketoflam-P Tablet is a medication manufactured by Lupin Ltd., primarily used for its pain-relieving and anti-inflammatory properties.

Composition

Ketoflam-P Tablet contains a combination of two active ingredients:

• Flupirtine (100 mg): A non-opioid analgesic that works by blocking pain signals from reaching the brain, thereby reducing pain perception. It also possesses muscle-relaxant properties.
• Paracetamol (325 mg): An analgesic (pain reliever) and antipyretic (fever reducer) that acts by inhibiting the release of certain chemical messengers, such as prostaglandins, which are responsible for causing pain, inflammation, and fever.

Uses

Ketoflam-P Tablet is prescribed for the management of various types of pain and associated conditions, including:

• Acute and chronic pain
• Inflammation
• Rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis
• Muscle pain (myalgia), back pain, joint pain
• Headache, including tension headaches and migraines
• Fever
• Toothache and pain after dental extraction
• Ear and throat pain
• Menstrual pain (dysmenorrhea)
• Postoperative pain
• Cancer pain and neuropathic pain

Dosage and Administration

The dosage and duration of Ketoflam-P Tablet should be strictly followed as prescribed by a healthcare provider, as it depends on the specific condition and severity of symptoms.

• Swallow the tablet whole with water; do not crush, break, or chew it.
• It is generally advised to take Ketoflam-P Tablet with food to enhance absorption and prevent stomach upset.
• Do not exceed the recommended dosage or duration of use.

Side Effects

Common side effects may include:

• Nausea, vomiting, abdominal discomfort
• Diarrhea, constipation, heartburn, flatulence
• Dry mouth
• Dizziness, headache, drowsiness, fatigue
• Depression, disorientation, shaking (tremors), hallucinations, sleep problems
• Increased sweating, loss of appetite, restlessness, nervousness

Serious side effects are possible. Immediately inform your doctor if you experience:

• Worsening or bothersome common side effects
• Signs of liver damage such as nausea, vomiting, jaundice (yellowed skin and eyes), abdominal pain, loss of appetite, itchy skin, or dark-colored urine
• Severe allergic reactions including swelling of the face, lips, tongue, or throat causing difficulty in breathing
• History of stomach ulcers or gastrointestinal bleeding

Precautions

• Allergies: Avoid using Ketoflam-P Tablet if you are allergic to flupirtine, paracetamol, or other analgesics/painkillers.
• Medical Conditions: Inform your doctor if you have a history of stomach ulcers, bleeding, high blood pressure, or any heart, kidney, or liver issues, including active liver disease, hepatic encephalopathy, chronic alcoholism, or cholestasis. Close monitoring of liver function is necessary for patients with liver impairment.
• Elderly Patients: Dosage adjustments may be required for individuals above 65 years of age.
• Pregnancy and Breastfeeding: Consult your doctor before using this medicine if you are pregnant or breastfeeding. It is generally not recommended during pregnancy unless clearly necessary, and may be unsafe during breastfeeding as it could pass into breast milk.
• Alcohol Consumption: Avoid alcohol while taking Ketoflam-P Tablet, as it can intensify drowsiness and increase the risk of liver damage.
• Driving and Operating Machinery: Do not drive or operate heavy machinery if you experience dizziness or drowsiness after taking this medicine.
• Children: Ketoflam-P Tablet is generally not recommended for children and adolescents under 18 years of age. For children below six years, consult your doctor for appropriate dosage adjustments.
• Drug Interactions: Inform your doctor about all other medications, supplements, or herbal products you are currently taking, as they may interact with Ketoflam-P Tablet. Specific interactions may occur with medicines like sedatives, carbamazepine, warfarin, chloramphenicol, colestyramine, metoclopramide, and domperidone.
• Duration of Use: This medication is intended for short-term pain relief. The duration of treatment should be determined by your doctor.

Storage

Store Ketoflam-P Tablet in a cool and dry place, ideally below 25°C or 30°C. Protect it from direct sunlight, moisture, and heat. Keep it out of the reach and sight of children. Ensure the medicine is used before its expiry date.

Here are the most frequently asked questions about KETOFLAM P TAB:

What is Ketoflam P Tablet used for?

Ketoflam P Tablet is a combination medication containing Flupirtine and Paracetamol (Acetaminophen) used for relieving acute and chronic pain. It is commonly prescribed for conditions such as headache, fever, joint pain, muscle pain (myalgia), dysmenorrhea (period pain), toothache after dental extraction, and postoperative pain. It also helps manage pain and inflammation associated with conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

How does Ketoflam P Tablet work?

Ketoflam P Tablet contains two active ingredients: Flupirtine and Paracetamol. Flupirtine is a non-opioid analgesic that works by blocking the transmission of pain signals to the brain, thereby lowering pain perception. It also has muscle relaxant properties. Paracetamol acts as both an analgesic (pain reliever) and an antipyretic (fever reducer) by inhibiting the release of certain chemical messengers (prostaglandins) in the body that cause pain, inflammation, and fever. Together, they provide comprehensive relief from pain and associated symptoms.

What is the usual dosage of Ketoflam P Tablet?

The dose and duration of Ketoflam P Tablet depend on your medical condition and its severity, as determined by your doctor. It should be taken as directed by your physician. For conditions like back pain, a common recommendation is one tablet, taken orally after a meal, three times daily. It is crucial not to exceed the prescribed dose or duration without consulting your doctor. Swallow the tablet whole with a glass of water; do not crush, break, or chew it.

What are the possible side effects of Ketoflam P Tablet?

Common side effects of Ketoflam P Tablet may include nausea, vomiting, abdominal discomfort, indigestion, diarrhoea, constipation, heartburn, drowsiness, dizziness, headache, tiredness, dry mouth, increased sweating, loss of appetite, sleeping problems, and shakiness. Most of these side effects are temporary and usually resolve over time. However, if any side effects persist or worsen, it is important to contact your doctor.

Is Ketoflam P Tablet safe during pregnancy or breastfeeding?

Ketoflam P Tablet is generally not recommended for use during pregnancy as there is limited safety data available in pregnant women, and some animal studies have shown harmful effects on the developing baby. Similarly, components of Ketoflam P Tablet can pass into breast milk, so it is generally not recommended during breastfeeding. It is crucial to consult your doctor before taking this medicine if you are pregnant, planning a pregnancy, or breastfeeding, so they can weigh the benefits against the potential risks.

Can Ketoflam P Tablet be taken with other medications?

Ketoflam P Tablet may interact with certain medications. Inform your doctor about all the medicines, supplements, or herbal products you are currently taking to avoid any possible interactions. Specific interactions may occur with:

• Anticoagulants (blood thinners) like warfarin.
• Anticonvulsants such as carbamazepine or phenytoin.
• Antidepressants like fluoxetine or sertraline.
• Other pain relievers, as this can increase the risk of liver damage due to high paracetamol levels.
• Medicines affecting the liver (e.g., rifampicin, phenobarbital), sedatives, chloramphenicol, colestyramine, metoclopramide, and domperidone.

What precautions should be taken while using Ketoflam P Tablet?

Several precautions should be observed:

• Liver Disease: Ketoflam P Tablet contains paracetamol, which can cause liver damage. It should be used with caution in patients with liver disease, and liver function should be closely monitored. Its use is not recommended in severe or active liver disease.
• Kidney Disease: Use with caution in patients with kidney disease, and dose adjustments may be needed.
• Alcohol: Avoid consuming alcohol while taking this medicine as it can increase the risk of liver damage and intensify side effects like drowsiness.
• Driving/Operating Machinery: This medicine can cause drowsiness and dizziness, so avoid driving or operating heavy machinery if you experience these symptoms.
• Allergies: Do not take if you are allergic to flupirtine, paracetamol, or any other ingredients of the tablet.
• Other conditions: Inform your doctor if you have a history of stomach ulcers, bleeding, high blood pressure, heart problems, brain disorders, myasthenia gravis (chronic neuromuscular disease), or chronic alcoholism.
• Age: It is generally not recommended for children younger than 6 or 18 years, depending on the source, and caution is advised for elderly patients (above 65 years).

What happens if a dose of Ketoflam P Tablet is missed?

If you miss a dose of Ketoflam P Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Ketoflam P Tablet be stored?

Store Ketoflam P Tablet in its original container at room temperature (20-25°C), in a cool and dry place. Protect it from direct sunlight, moisture, and heat. Always keep the medicine out of the sight and reach of children and pets. Dispose of any unused medicine properly.