Sensiclav 375

SENSICLAV 375

SENSICLAV 375, manufactured by MACLEODS PHARMACEUTICALS PVT LTD, is an antibiotic medication used to treat various bacterial infections.

• Name:

  • Brand Name: SENSICLAV 375, SENSICLAV-375mg Tablet
  • Common Name: Amoxicillin and Clavulanic Acid Tablet

• Composition: Each tablet contains Amoxicillin (250mg) and Clavulanic Acid (125mg). Amoxicillin is a penicillin-class antibiotic that works by inhibiting bacterial cell wall synthesis, while Clavulanic Acid is a beta-lactamase inhibitor that protects amoxicillin from bacterial enzymes, enhancing its effectiveness against resistant strains.

• Uses: SENSICLAV 375 is prescribed for a wide range of bacterial infections, including:

  • Respiratory tract infections (e.g., sinusitis, acute bronchitis, pneumonia)
  • Urinary tract infections (UTIs)
  • Ear infections (e.g., acute otitis media)
  • Skin and soft tissue infections (e.g., cellulitis, dental abscesses, impetigo)
  • Bone and joint infections
  • Intra-abdominal infections
  • Genital tract infections It is not effective against viral infections like the common cold or flu.

• Dosage and Administration: Take SENSICLAV 375 as directed by a doctor. It is generally recommended to take the tablet with a meal to reduce the risk of stomach upset. Swallow the tablet whole; do not crush or chew it. Complete the full course of treatment even if symptoms improve to prevent resistance and recurrence.

• Side Effects: Common side effects include:

  • Diarrhoea
  • Nausea and vomiting
  • Indigestion/stomach pain
  • Mucocutaneous candidiasis (fungal infection of skin or mucous membranes)
  • Headache or dizziness Serious side effects, though rare, may include allergic reactions (rash, facial swelling, difficulty breathing) and liver inflammation or jaundice.

• Precautions:

  • Allergies: Contraindicated in patients with a history of allergy to penicillin or cephalosporin antibiotics.
  • Liver/Kidney Conditions: Use with caution in patients with kidney problems, and it is not recommended for those with a history of cholestatic jaundice or hepatic dysfunction.
  • Pregnancy and Breastfeeding: Consult a doctor before use if pregnant or breastfeeding.
  • Alcohol: Avoid alcohol consumption as it may reduce effectiveness and cause dizziness.
  • Drug Interactions: Inform your doctor about all current medications, especially allopurinol, probenecid, warfarin, methotrexate, and mycophenolate mofetil.

• Storage: Store the medicine in a tightly closed container at room temperature (ideally below 25°C or below 30°C). Protect from light and moisture. Keep out of reach of children.

What is Sensiclav 375 Tablet used for?

Sensiclav 375 Tablet is an antibiotic medication used to treat a wide range of bacterial infections. It is effective against infections affecting the lungs (like pneumonia), ears (acute otitis media), nasal sinuses (acute bacterial sinusitis), urinary tract, skin, soft tissues, dental structures, and bones and joints. It is important to note that this medication is not effective against viral infections, such as the common cold or flu.

How does Sensiclav 375 Tablet work?

Sensiclav 375 Tablet contains two active ingredients: Amoxicillin (250mg) and Clavulanic Acid (125mg). Amoxicillin is a penicillin-class antibiotic that works by preventing the formation of the bacterial cell wall, which is essential for the bacteria's survival, leading to their death. Clavulanic Acid is a beta-lactamase inhibitor. Some bacteria produce an enzyme called beta-lactamase, which can destroy amoxicillin and make it ineffective. Clavulanic Acid inactivates this enzyme, thereby protecting amoxicillin and enhancing its effectiveness against resistant bacteria.

What is the usual dosage?

The dosage of Sensiclav 375 Tablet is determined by a doctor based on the specific condition being treated, its severity, and individual factors like age, gender, and medical history. It is usually taken orally with a meal to minimize the risk of stomach upset. It should be taken regularly at evenly spaced intervals, ideally at the same time each day, as prescribed by your healthcare professional. It is crucial to complete the full course of this antibiotic, even if symptoms improve, to prevent the survival of resistant bacteria and a recurrent infection. Do not crush, chew, or break the tablet; swallow it whole with water.

What are the possible side effects?

Common side effects of Sensiclav 375 Tablet may include nausea, vomiting, diarrhea, indigestion, and stomach pain. Other possible side effects include mucocutaneous candidiasis (a fungal infection), headache, dizziness, and skin rashes. If these side effects persist, worsen, or if you experience signs of an allergic reaction such as rash, itching, facial swelling, or difficulty breathing, seek immediate medical attention.

Is it safe during pregnancy or breastfeeding?

Pregnancy: Sensiclav 375 Tablet should be used with caution during pregnancy and only if considered essential by your doctor. While animal studies have shown low or no adverse effects on the fetus, human studies are limited. It is important to consult your doctor before taking any medication during pregnancy.

Breastfeeding: Sensiclav 375 Tablet should be used with caution during breastfeeding as its components can pass into breast milk. It may cause fungal infections of the mouth or diarrhea in the infant. Consult your doctor, who will weigh the benefits against the potential risks.

Can it be taken with other medications?

It is crucial to inform your doctor about all current medications, supplements, or herbal products you are taking to avoid potential drug interactions. Sensiclav 375 Tablet may interact with certain medicines, including:

• Allopurinol and Probenecid: May increase the risk of skin rash and increase amoxicillin levels.
• Warfarin, Acenocoumarol, or Heparin: May increase the risk of bleeding, so regular blood tests (like PT-INR) are advised.
• Methotrexate: May lead to increased side effects.
• Oral contraceptives (birth control pills): The effectiveness of birth control pills may be decreased, so alternative contraception methods might be necessary.
• Mycophenolate mofetil.

What precautions should be taken?

Before taking Sensiclav 375 Tablet, inform your doctor if you have any allergies to antibiotics (especially penicillin or cephalosporins), or if you have kidney or liver problems. Individuals with a history of cholestatic jaundice or hepatic dysfunction should avoid this medication. If you have glandular fever, inform your doctor. It is advised not to drive or operate machines if you experience dizziness, fits, or allergic reactions while taking this medicine. Avoid alcohol consumption, as it may worsen side effects like dizziness.

What happens if a dose is missed?

If you miss a dose of Sensiclav 375 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one. It is crucial not to miss any dose of antibiotics, as this can lead to treatment failure and allow bacteria to grow again.

How should it be stored?

Sensiclav 375 Tablet should be stored in a cool and dry place, protected from direct sunlight, moisture, and heat. The ideal storage temperature is below 25°C or 30°C. Keep it out of reach of children and pets. Do not use expired or damaged medicines and dispose of any unused medicine properly.