Rabetru Dsrtab

RABETRU DSRTAB by IATROS PHARMACEUTICALS

Name

• Brand Name: Rabetru DSR 30 mg/20 mg Tablet
• Manufacturer: IATROS PHARMACEUTICALS

Composition

• Each tablet contains:
  • Domperidone: 30 mg
  • Rabeprazole: 20 mg

Uses Rabetru DSR is a combination medication primarily used to treat conditions related to excessive stomach acid and gastrointestinal motility issues. It is prescribed for:

• Gastroesophageal Reflux Disease (GERD), including acid reflux and heartburn
• Peptic ulcer disease (stomach and duodenal ulcers)
• Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumor)
• Erosive esophagitis (inflammation of the food pipe lining)
• Relieving nausea and vomiting associated with gastrointestinal problems
• Supporting digestive health and reducing discomfort from gas, bloating, and indigestion

Dosage and Administration

• Take Rabetru DSR as advised by your doctor, typically without food, one hour before a meal or the first meal of the day.
• Swallow the tablet whole; do not chew, crush, or break it.
• The dosage and duration depend on the patient's condition and response to treatment.

Side Effects Common side effects may include:

• Headache, dizziness
• Diarrhea, nausea, abdominal pain, vomiting, flatulence
• Dry mouth
• Arthralgia (joint pain), weakness
• Pharyngitis, cough, inflammation of the nose, nasal congestion
• Insomnia, constipation

A serious, though rare, side effect can be an increased risk of irregular heartbeat (arrhythmias), especially in individuals over 60 years of age.

Precautions

• Inform your doctor if you have known allergies to rabeprazole, domperidone, or any other ingredients.
• Use with caution in patients with kidney or liver disease; it is not recommended for moderate to severe liver disease.
• Prolonged intake may lead to deficiencies in Vitamin B12 and magnesium, and can mask symptoms of gastric cancer.
• Avoid alcohol consumption and smoking as they can worsen acid reflux and reduce the medicine's effectiveness.
• It may interact with blood thinners, antifungals, anti-HIV drugs, iron supplements, and anti-cancer medications.
• Consult a doctor if pregnant or breastfeeding, as it may be unsafe or pass into breast milk.
• This medicine may cause dizziness and sleepiness; avoid driving or operating machinery until you know how it affects you.
• Not recommended for children below 5 years of age.

Storage

• Store at room temperature (below 30°C) in a cool and dry place.
• Protect from light and moisture.
• Keep out of reach of children.

What is Rabetru DSR TAB used for?

Rabetru DSR TAB is a combination medication used to treat conditions related to excessive stomach acid. It is primarily prescribed for gastroesophageal reflux disease (GERD), which causes symptoms like acidity, heartburn, and irritation. It also treats stomach ulcers (peptic ulcer disease) and Zollinger-Ellison syndrome, a condition characterized by overproduction of acid due to a pancreatic tumor. Additionally, it helps alleviate nausea associated with acid reflux and promotes the healing of acid-induced damage in the esophagus.

How does Rabetru DSR TAB work?

Rabetru DSR TAB contains two active ingredients: Rabeprazole and Domperidone. Rabeprazole is a proton pump inhibitor (PPI) that reduces stomach acid by blocking the action of an enzyme called H+/K+ ATPase (gastric proton pump), which is responsible for acid secretion. Domperidone is a prokinetic agent that increases the movement of the upper gastrointestinal tract, helping food move more easily through the stomach. It also blocks the chemoreceptor trigger zone (CTZ), which is the vomiting-inducing center in the brain, thereby controlling vomiting and nausea.

What is the usual dosage of Rabetru DSR TAB?

Rabetru DSR TAB should be taken as advised by your doctor, typically once daily. It is generally recommended to take it without food, ideally before the first meal of the day or on an empty stomach. The tablet should be swallowed whole and not chewed, crushed, or broken. The exact dosage and duration of treatment will depend on your medical condition and response to the medication.

What are the possible side effects of Rabetru DSR TAB?

Common side effects of Rabetru DSR TAB can include headache, diarrhea, nausea, abdominal pain, vomiting, flatulence (gas), dizziness, dry mouth, and joint pain. While these are usually temporary, if they persist or worsen, you should contact your doctor. In some cases, it may cause dizziness, sleepiness, or blurred vision, and there's a low risk of developing an irregular heartbeat (serious arrhythmias), especially in patients over 60 years of age. Prolonged use may also lead to deficiencies in Vitamin B12, calcium, magnesium, and Vitamin D.

Is Rabetru DSR TAB safe during pregnancy or breastfeeding?

There is conflicting information regarding the safety of Rabetru DSR TAB during pregnancy and breastfeeding. Some sources indicate it may be safe for use during pregnancy, while others advise consultation with a doctor, stating that animal studies have shown harmful effects on the developing baby and that it may be unsafe during pregnancy. For breastfeeding, some sources state that Domperidone passes into breast milk but no evidence of risk has been reported, while others suggest it is probably unsafe and that limited human data suggests it may harm the baby. Therefore, it is crucial to consult your doctor if you are pregnant, planning pregnancy, or breastfeeding before starting or continuing treatment with Rabetru DSR TAB, as your doctor will weigh the benefits against potential risks.

Can Rabetru DSR TAB be taken with other medications?

Rabetru DSR TAB may interact with several other medications. It is important to inform your doctor about all other medicines you are taking, including supplements and herbal products, to prevent potential interactions. Specific medications that may interact include blood thinners, antifungals, anti-HIV drugs, iron supplements, and anti-cancer medications.

What precautions should be taken while using Rabetru DSR TAB?

Several precautions should be observed when taking Rabetru DSR TAB. It should be used with caution in patients with kidney or liver disease, and dose adjustments may be needed; use is generally not recommended in moderate to severe liver disease. Alcohol consumption and smoking should be avoided, as alcohol can increase stomach acid and smoking can damage the valve preventing acid reflux. This medicine may cause dizziness and sleepiness, so avoid driving or operating heavy machinery until you know how it affects you. Inform your doctor if you have a history of gastric cancer, as the medication may mask its symptoms.

What happens if a dose of Rabetru DSR TAB is missed?

If you miss a dose of Rabetru DSR TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Rabetru DSR TAB be stored?

Rabetru DSR TAB should be stored in a cool and dry place, away from direct sunlight. It should be kept in its original packaging and out of reach of children and pets. Do not use the medicine after its expiry date.