Sitazit 100 Mg Tablet ( 10 Tablet )

SITAZIT 100 MG TABLET

Name

• Brand Name: Sitazit 100mg Tablet
• Common Name (Active Ingredient): Sitagliptin

Composition

• Active Ingredients: Sitagliptin (100 mg)

Uses

Sitazit 100mg Tablet is primarily used for the management of Type 2 Diabetes Mellitus in adults. It functions as a dipeptidyl peptidase-4 (DPP-4) inhibitor, working to control blood sugar levels when used in conjunction with a healthy diet and regular exercise regimen. This medication helps improve insulin sensitivity and reduces glucose production in the liver, contributing to better blood sugar regulation and aiding in the prevention of serious diabetes complications such as kidney damage and blindness.

Dosage and Administration

Sitazit 100mg Tablet is typically taken once daily, with or without food. It is recommended to take the tablet at a fixed time each day to ensure consistency. The tablet should be swallowed whole with water and should not be chewed, crushed, or broken. The dosage and frequency are determined by a healthcare professional based on the patient's condition and blood sugar levels. In cases of a missed dose, it should be taken as soon as remembered, but if it is close to the next scheduled dose, the missed dose should be skipped.

Side Effects

Common Side Effects:

• Headache
• Nausea
• Diarrhea
• Stomach discomfort
• Skin rash, itching
• Common cold, upper respiratory tract infections (sore throat, cough)
• Nasopharyngitis (inflammation of the nasal passages)
• Drowsiness or fatigue (less common)
• Dry mouth or throat (less common)

Serious Side Effects (Seek immediate medical attention):

• Pancreatitis (inflammation of the pancreas)
• Hypoglycemia (low blood sugar level), especially when combined with other antidiabetic medicines like insulin or sulfonylurea
• Severe allergic reactions such as rash, itching, swelling (including angioedema), or difficulty breathing (anaphylaxis, Stevens-Johnson syndrome)
• Acute kidney injury
• Heart failure (in rare cases)

Precautions

• Allergies: Do not take if allergic to Sitagliptin or any other components of the tablet.
• Medical Conditions: Inform your doctor about any history of kidney disease (especially severe impairment or end-stage renal disease), liver problems, pancreatitis, gallstones, high blood triglyceride levels, Type 1 diabetes, or diabetic ketoacidosis.
• Pregnancy and Breastfeeding: Consult your doctor if pregnant or breastfeeding. Caution is advised during pregnancy, and use is generally contraindicated or probably unsafe during breastfeeding unless deemed necessary by a doctor.
• Drug Interactions: Concomitant use with insulin or insulin secretagogues (e.g., glimepiride, glyburide) may increase the risk of hypoglycemia, necessitating a possible dosage reduction of the co-administered medication.
• Alcohol: Avoid alcohol consumption as it can increase drowsiness and affect blood sugar levels.
• Driving and Operating Machinery: Exercise caution if driving or operating machinery, as the medicine may cause dizziness or fluctuations in blood sugar levels.
• Children: Sitazit 100mg Tablet is not recommended for children below 18 years of age.
• Discontinuation: Do not stop taking the medication without consulting your doctor, as abrupt discontinuation can lead to an increase in blood sugar levels.

Storage

Store Sitazit 100mg Tablet below 30°C (some sources suggest below 25°C) in a cool and dry place. Keep it away from direct sunlight and moisture, and out of the reach of children and pets.

SITAZIT 100 MG TABLET contains Sitagliptin, an oral medication used to manage type 2 diabetes mellitus. It belongs to a class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors. SITAZIT 100 MG TABLET works in conjunction with diet and exercise to help improve blood sugar control in adults.

Here are some frequently asked questions about SITAZIT 100 MG TABLET:

What is SITAZIT 100 MG TABLET used for?

SITAZIT 100 MG TABLET is prescribed to lower high blood sugar levels in adults with type 2 diabetes mellitus. It is used as an adjunct to diet and exercise to improve glycemic control. It is not used to treat type 1 diabetes.

How does SITAZIT 100 MG TABLET work?

SITAZIT 100 MG TABLET (Sitagliptin) works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). This enzyme normally breaks down incretin hormones, such as GLP-1 and GIP, which are released after meals. By inhibiting DPP-4, Sitagliptin increases the levels of active incretins, leading to enhanced insulin secretion and reduced glucagon production by the pancreas, both in a glucose-dependent manner. This helps to lower blood glucose levels and improve overall blood sugar control.

What is the usual dosage of SITAZIT 100 MG TABLET?

The usual recommended dose for adults with type 2 diabetes is 100 milligrams (mg) once a day. This medication can be taken with or without food. Your doctor may adjust the dose to 25 mg or 50 mg daily if you have kidney problems.

What are the possible side effects of SITAZIT 100 MG TABLET?

Common side effects include headaches, upper respiratory tract infections (such as a stuffy or runny nose and sore throat), diarrhea, stomach pain, and nausea. Serious, but less common, side effects can include severe stomach pains (a sign of pancreatitis), severe and disabling joint pain, low blood sugar (especially when taken with other diabetes medications like insulin or sulfonylureas), kidney problems, and serious allergic reactions (e.g., rash, hives, swelling of the face, lips, tongue, or throat).

Is SITAZIT 100 MG TABLET safe during pregnancy or breastfeeding?

SITAZIT 100 MG TABLET (Sitagliptin) is generally not recommended during pregnancy or breastfeeding due to limited information on its safety and effects on a developing baby or a breastfed infant. If you are pregnant, planning to become pregnant, or breastfeeding, you should consult your doctor, who may recommend an alternative treatment.

Can SITAZIT 100 MG TABLET be taken with other medications?

Yes, SITAZIT 100 MG TABLET can be taken with other medications, but caution is advised as some interactions can occur. When combined with insulin or sulfonylureas, there is an increased risk of hypoglycemia, and dosage adjustments of these concomitant medications may be necessary. ACE inhibitors taken with Sitagliptin may increase the risk of angioedema. It's important to inform your doctor about all prescription, nonprescription, vitamin, nutritional supplement, and herbal products you are taking to ensure safe co-administration.

What precautions should be taken while using SITAZIT 100 MG TABLET?

Inform your doctor if you have kidney or liver problems, a history of pancreatitis, gallstones, high triglyceride levels, type 1 diabetes, diabetic ketoacidosis, heart failure, or a history of allergic reactions to Sitagliptin or any other medication. Your doctor may need to adjust the dose based on your kidney function or recommend alternative treatments.

What happens if a dose of SITAZIT 100 MG TABLET is missed?

If you miss a dose of SITAZIT 100 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the forgotten one.

How should SITAZIT 100 MG TABLET be stored?

SITAZIT 100 MG TABLET should be stored in a closed container at room temperature, ideally between 20°C to 25°C (68°F to 77°F), away from heat, moisture, and direct light. Keep it out of the reach of children.