Synaptol 150

SYNAPTOL 150

Name

Common Name: Synaptol 150 Tablet Brand Name: SYNAPTOL 150 by SUN PHARMA VV

Composition

SYNAPTOL 150 contains Tolperisone 150 mg as its active ingredient. It is classified as a centrally-acting muscle relaxant.

Uses

SYNAPTOL 150 is primarily used to relieve acute musculoskeletal pain, which includes pain originating from muscles, bones, or joints. It is effective in treating muscle spasms, stiffness, and pain, and can be used for conditions such as severe back pain, and spasticity associated with neurological disorders like multiple sclerosis, stroke, spinal cord injuries, and Parkinson's disease. It works by reducing muscle contractions and stiffness without decreasing muscle strength, and by increasing blood supply to the muscles, thereby improving movement and reducing pain.

Dosage and Administration

The typical dosage for adults is one tablet (150 mg) taken once or twice a day. It is recommended to take SYNAPTOL 150 with food or after a meal to prevent stomach discomfort and reduce the chance of side effects. Tablets should be swallowed whole and not crushed or chewed. It is important to follow the doctor's prescribed dosage and not to adjust or stop the medication suddenly without consulting a healthcare provider.

Side Effects

Common Side Effects:

• Dizziness or light-headedness
• Sleepiness/Drowsiness
• Diarrhoea
• Sweating
• Abdominal pain/Gastrointestinal disturbances (nausea, vomiting, indigestion, constipation)
• Weakness/Fatigue/Lassitude
• Headache
• Dry mouth

Serious Side Effects (Rare):

• Severe allergic reactions (flushing, rash, wheezing, severe itching, swelling of the face, lips, tongue, and/or throat, difficulty breathing, difficulty swallowing, low blood pressure, fast heartbeat, sudden decrease in blood pressure). If these occur, stop the medication and seek immediate medical attention.

Precautions

• Allergies: Inform your doctor about any known allergies to the components of SYNAPTOL 150.
• Medical Conditions: Caution is advised if you have myasthenia gravis (muscle weakness), asthma, hay fever, severe liver impairment, or severe kidney impairment.
• Pregnancy and Breastfeeding: SYNAPTOL 150 should be used with caution during pregnancy only if clearly necessary and advised by a doctor. It is not recommended for use in breastfeeding women.
• Alcohol: Avoid consuming alcohol while taking this medication as it may increase drowsiness and dizziness.
• Driving and Operating Machinery: Due to potential dizziness or sleepiness, do not drive or operate heavy machinery until you understand how the medicine affects you.
• Long-term Use: Do not stop taking SYNAPTOL 150 suddenly, especially if used long-term, without consulting your doctor.
• Overdose: Do not take more than the prescribed dose. In case of suspected overdose, consult a doctor immediately.

Storage

Store SYNAPTOL 150 in a cool and dry place, away from direct sunlight and moisture. Keep it out of sight and reach of children. The recommended storage temperature is between 10ºC to 25ºC or below 30ºC.

SYNAPTOL 150, manufactured by SUN PHARMA VV, is a muscle relaxant medication. It contains Tolperisone as its active ingredient.

What is SYNAPTOL 150 used for?

SYNAPTOL 150 is primarily used as a muscle relaxer to treat acute musculoskeletal pain and associated symptoms such as rigidity, tension, stiffness, and muscle spasms. It can also be used for conditions like severe back pain, post-cerebral stroke spasticity, and trapezitis. It helps manage involuntary muscle contractions and improves mobility and flexibility.

How does SYNAPTOL 150 work?

SYNAPTOL 150 (Tolperisone) works as a centrally acting muscle relaxant. It acts on centers in the brain and spinal cord to relieve muscle stiffness or spasms without reducing muscle strength. It does this by blocking voltage-gated sodium and calcium channels in the brain stem and spinal cord, which helps suppress certain reflexes and reduce muscle contractions. Additionally, it can induce vasodilation, increasing blood flow to skeletal muscles, and stopping pain signals between nerves and the brain.

What is the usual dosage?

The usual dosage of SYNAPTOL 150 (Tolperisone) for adults is typically 50-150 mg, three times a day. It should be taken with or after food or a glass of milk to prevent an upset stomach and reduce side effects. The dosage and duration of treatment are determined by a doctor based on the patient's condition and response to the medication.

What are the possible side effects?

Common side effects of SYNAPTOL 150 include sleepiness, weakness, dizziness, dry mouth, nausea, vomiting, abdominal pain, fatigue, and low blood pressure. If any side effects persist or worsen, it is important to inform your doctor.

Is it safe during pregnancy or breastfeeding?

SYNAPTOL 150 is generally advised with caution during pregnancy and should only be used if the benefits outweigh the risks, especially during the initial three months. It is not recommended for use in breastfeeding women as it may cause harm to the newborn baby. Always consult your doctor before taking this medication if you are pregnant or breastfeeding.

Can it be taken with other medications?

SYNAPTOL 150 can interact with certain medications. For example, when taken with benzodiazepines (like diazepam or lorazepam) or opioids (like morphine or codeine), it can amplify sedative effects and increase drowsiness. Concurrent use with other muscle relaxants may increase the risk of side effects. Inform your doctor about all medications, herbal preparations, and supplements you are currently taking to avoid potential drug interactions.

What precautions should be taken?

SYNAPTOL 150 may cause dizziness or sleepiness, so avoid driving or engaging in activities requiring concentration until you know how it affects you. Alcohol consumption should be avoided or limited as it may cause excessive drowsiness. Caution is advised in patients with liver or kidney impairment, Myasthenia Gravis, and respiratory depression. Do not stop taking it suddenly if you have been on it for a long time, without consulting your doctor.

What happens if a dose is missed?

If you miss a dose of SYNAPTOL 150, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should it be stored?

SYNAPTOL 150 should be stored below 30°C, in a cool and dry place. It should be protected from moisture and light and kept out of sight and reach of children.