Polmakem 2mg Tab

POLMAKEM 2MG TABLET

POLMAKEM 2MG TABLET, manufactured by ALKEM LABORATORIES LTD., is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for pain relief and reducing inflammation. It is often referred to as POLMAKEM 2mg Capsule in various sources, with the same active ingredient and dosage.

• Name:
  • Brand Name: POLMAKEM 2MG TABLET (also seen as POLMAKEM 2mg Capsule)
  • Common Name: Polmacoxib
• Composition:
  • Active Ingredient: Polmacoxib (2mg)
• Uses:
  • Primarily prescribed for the treatment of osteoarthritis, especially affecting the knee and hip joints.
  • Provides relief from mild to moderate pain and reduces inflammation associated with various musculoskeletal disorders.
  • Manages other inflammatory disorders as advised by a healthcare provider.
• Dosage and Administration:
  • Take POLMAKEM 2MG TABLET exactly as prescribed by your doctor.
  • It is typically taken orally, with or without food, to reduce gastrointestinal discomfort, and should be swallowed whole with a sufficient amount of water. Do not crush or chew the tablet/capsule.
  • Maintain consistent timing for better efficacy. Do not exceed the recommended dosage.
  • If a dose is missed, take it as soon as you remember unless it is almost time for your next dose; in that case, skip the missed dose and continue the regular schedule.
• Side Effects:
  • Common side effects: Nausea, headache, upset stomach, dizziness, stomach pain, heartburn, gas, constipation, and diarrhea.
  • Serious side effects (seek immediate medical attention): Allergic reactions (rash, swelling), gastrointestinal bleeding, liver damage, chest pain, difficulty breathing, or signs of acute pancreatitis.
• Precautions:
  • Inform your doctor about any allergies, pre-existing medical conditions (such as cardiovascular diseases, gastrointestinal bleeding, peptic ulcers, liver or kidney impairment, heart failure, asthma, diabetes, autoimmune disorders, or bleeding disorders), or other medications you are currently taking.
  • Interactions may occur with blood-thinning medications (e.g., warfarin), diuretics, ACE inhibitors or angiotensin II receptor blockers, corticosteroids, other anti-inflammatory drugs, ketoconazole, erythromycin, or aspirin.
  • Avoid alcohol consumption as it may increase the risk of stomach bleeding and other side effects.
  • Exercise caution when driving or operating heavy machinery, as this medicine may cause drowsiness or dizziness.
  • Not recommended during the last three months of pregnancy, and use with caution in early pregnancy and while breastfeeding.
  • Use with caution in the elderly, as they may be more susceptible to side effects.
  • Not recommended for children below a certain age.
• Storage:
  • Store in a cool, dry place below 25°C or 30°C.
  • Protect from light and moisture.
  • Keep the medication out of reach of children and pets.

What is POLMAKEM 2mg Tablet used for?

POLMAKEM 2mg Tablet, containing Polmacoxib, is primarily used for the treatment of osteoarthritis, particularly in the knee and hip joints. It helps to relieve pain, reduce inflammation, and alleviate stiffness associated with this chronic condition. It is also used for the management of mild to moderate pain and inflammation in musculoskeletal disorders.

How does POLMAKEM 2mg Tablet work?

POLMAKEM 2mg Tablet works as a selective cyclooxygenase-2 (COX-2) inhibitor, a type of nonsteroidal anti-inflammatory drug (NSAID). Its active ingredient, Polmacoxib, specifically targets and blocks the COX-2 enzyme, which is responsible for producing prostaglandins – substances that cause pain, swelling, and inflammation. By inhibiting these prostaglandins at the sites of inflammation, POLMAKEM helps reduce discomfort and improve joint mobility. This selective action on COX-2 may also offer gastrointestinal protection compared to traditional NSAIDs that block both COX-1 and COX-2 enzymes.

What is the usual dosage for POLMAKEM 2mg Tablet?

The usual dosage of POLMAKEM 2mg Tablet is one film-coated tablet (2mg) once a day, to be taken after a meal, or as directed by your healthcare provider. It is crucial to follow your doctor's instructions carefully regarding dosage and duration, as it may vary based on your specific medical condition and response to treatment. Do not exceed the prescribed 2mg daily dose.

What are the possible side effects of POLMAKEM 2mg Tablet?

Common side effects of POLMAKEM 2mg Tablet may include headache, nausea, stomach pain, dizziness, heartburn, gas, constipation, diarrhea, upset stomach, or indigestion. More serious side effects, though less common, can include allergic reactions, gastrointestinal bleeding, or liver damage. It's important to note that it may also worsen existing heart conditions, increasing the risk of heart attack or stroke, and can aggravate stomach ulcers. Additionally, there have been reports of acute pancreatitis linked to Polmacoxib. If you experience any severe or persistent side effects, contact your doctor immediately.

Is POLMAKEM 2mg Tablet safe during pregnancy or breastfeeding?

POLMAKEM 2mg Tablet is generally not recommended during pregnancy, especially during the last three months and early months, as it may potentially harm the unborn baby. For breastfeeding women, caution is advised, and it should only be taken if clearly prescribed by your doctor, as there is limited information on its presence in breast milk. Always consult your healthcare provider if you are pregnant, planning to conceive, or breastfeeding before taking this medicine.

Can POLMAKEM 2mg Tablet be taken with other medications?

POLMAKEM 2mg Tablet can interact with various medications. It is essential to inform your doctor about all medicines, including over-the-counter drugs and supplements, you are currently taking. Interactions can occur with:

• Anticoagulants (e.g., warfarin, heparin): May increase the risk of bleeding.
• Other NSAIDs (e.g., aspirin, ibuprofen, diclofenac): May increase the risk of stomach bleeding and ulcers.
• Diuretics (e.g., furosemide, hydrochlorothiazide): May reduce their effectiveness and affect kidney function.
• ACE inhibitors or angiotensin II receptor blockers (blood pressure medications): May lessen their blood pressure-lowering effect.
• Corticosteroids: May heighten gastrointestinal risks. It is recommended to consult your doctor before taking POLMAKEM with any other pain medications.

What precautions should be taken while taking POLMAKEM 2mg Tablet?

Several precautions should be observed when taking POLMAKEM 2mg Tablet. Inform your doctor about any allergies, pre-existing conditions such as stomach problems (ulcers, bleeding disorders), heart conditions, diabetes, severe kidney or liver impairment, autoimmune disorders, or asthma. Avoid consuming alcohol while on this medication, as it can increase the risk of stomach problems and bleeding. Exercise caution when driving or operating heavy machinery if you experience dizziness or headaches. It is generally recommended to take this medicine with food to minimize stomach upset. It is contraindicated if you have a known allergy to Polmacoxib or other NSAIDs, a history of stomach bleeding or ulcers, increased bleeding tendency, or severe heart, kidney, or liver failure. Use with caution in elderly patients and it is not recommended for children below a certain age.

What happens if a dose of POLMAKEM 2mg Tablet is missed?

If you miss a dose of POLMAKEM 2mg Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take an extra or double dose to compensate for the missed one.

How should POLMAKEM 2mg Tablet be stored?

POLMAKEM 2mg Tablet should be stored below 25°C or 30°C in a cool and dry place. Keep the medication out of the reach of children and pets, and protect it from light and moisture.