Isaz 40mg Tab

ISAZ D 30mg/40mg Capsule

ISAZ D 30mg/40mg Capsule, manufactured by Isakura Healthcare Private Limited, is a combination medication used to manage various gastrointestinal disorders.

• Name: ISAZ D Capsule (Brand name).
• Composition: Each capsule contains Domperidone (30mg) and Esomeprazole (40mg).
  • Domperidone acts as a prokinetic, increasing the movement of the stomach and intestines to facilitate food passage and control vomiting.
  • Esomeprazole is a proton pump inhibitor (PPI) that reduces the amount of acid produced in the stomach, providing relief from acid-related indigestion and heartburn.
• Uses: It is primarily prescribed for:
  • Gastroesophageal Reflux Disease (GERD), including acid reflux, heartburn, and irritation.
  • Indigestion.
  • Gastric and duodenal ulcers.
  • Healing and maintenance to prevent relapse of erosive esophagitis.
  • Controlling hypersecretory conditions like Zollinger-Ellison syndrome.
  • Preventing nausea and vomiting.
• Dosage and Administration:
  • Take as directed by your doctor, usually on an empty stomach, at least one hour before the first meal of the day.
  • Swallow the capsule whole with water; do not crush or chew it.
  • Adhere to the prescribed duration to prevent symptom recurrence.
• Side Effects: Common side effects may include diarrhea, stomach pain, flatulence, dry mouth, dizziness, headache, and nausea. Serious side effects can include abnormal heartbeat (especially in patients over 60), fundic gland polyps, weak bones, and magnesium deficiency with long-term use.
• Precautions:
  • Avoid if hypersensitive to domperidone, esomeprazole, or other ingredients.
  • Use with caution in patients with kidney or liver disease.
  • Consult a doctor during pregnancy or breastfeeding, as it may be unsafe in pregnancy and is considered unsafe during breastfeeding.
  • May cause drowsiness or dizziness; avoid driving or operating machinery if affected.
  • Avoid alcohol consumption as it may worsen drowsiness and acidity.
  • Inform your doctor about all other medications, as some may interact.
• Storage: Store in its original container, tightly closed, in a cool and dry place (below 30°C or between 15-30°C). Keep it away from direct sunlight, children, and pets.

ISAZ 40MG TAB: Frequently Asked Questions

ISAZ 40MG TAB, manufactured by ISAKURA HEALTHCARE DIV., is a combination medicine containing Esomeprazole 40mg and Domperidone 30mg. It is primarily used to treat various gastrointestinal conditions.

What is ISAZ 40MG TAB used for?

ISAZ 40MG TAB is prescribed for the treatment of gastroesophageal reflux disease (GERD), commonly known as acid reflux, and indigestion. It helps alleviate symptoms such as heartburn, stomach pain, irritation due to excess stomach acid, and also aids in managing gastric and duodenal ulcers and Zollinger-Ellison syndrome. Additionally, it can help prevent nausea and vomiting induced by certain medications.

How does ISAZ 40MG TAB work?

This medicine combines two active ingredients: Esomeprazole and Domperidone. Esomeprazole is a proton pump inhibitor (PPI) that works by reducing the amount of acid produced in the stomach, which helps relieve acid-related indigestion and heartburn. Domperidone is a prokinetic that increases the movement of the stomach and intestines, facilitating food passage and helping to control vomiting by acting on the brain's vomiting control region.

What is the usual dosage for ISAZ 40MG TAB?

The dosage and duration of treatment should be strictly followed as advised by your doctor based on your individual condition. Generally, it is recommended to take ISAZ 40MG TAB on an empty stomach, typically one hour before a meal, preferably in the morning. The capsule should be swallowed whole with water and not crushed or chewed.

What are the possible side effects of ISAZ 40MG TAB?

Common side effects may include diarrhea, flatulence (gas), stomach pain, dry mouth, and headache. Some individuals may also experience dizziness or drowsiness. In rare cases, more serious side effects like irregular heartbeats (arrhythmias) can occur, especially in individuals over 60 years of age. If you experience persistent or severe side effects, consult your doctor immediately.

Is ISAZ 40MG TAB safe during pregnancy or breastfeeding?

Pregnancy: ISAZ 40MG TAB should be used with caution during pregnancy, and its use is generally not recommended as animal studies have shown potential harmful effects on the developing baby. Your doctor will weigh the benefits against potential risks before prescribing it.

Breastfeeding: ISAZ 40MG TAB is generally considered unsafe during breastfeeding. Data suggests that the drug may cause toxicity to the baby. However, some sources suggest that Esomeprazole passes into breast milk in very small amounts and is unlikely to cause side effects in breastfed babies, but Domperidone's safety during breastfeeding is a concern. It is crucial to consult your doctor, health visitor, or midwife regarding its use while breastfeeding.

Can ISAZ 40MG TAB be taken with other medications?

It is essential to inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins, as some medications can interact with ISAZ 40MG TAB. For example, certain CYP3A4 inhibitors (like ketoconazole, clarithromycin) can increase the risk of irregular heartbeats. The absorption of pH-dependent medications (e.g., digoxin, iron salts) may be altered. Co-administration with antiplatelet medicines like clopidogrel should be avoided.

What precautions should be taken while using ISAZ 40MG TAB?

Inform your doctor if you have a history of heart, liver, or kidney disease, stomach problems (such as bleeding or intestinal blockage), or a prolactin-releasing pituitary tumor (prolactinoma). Avoid consuming alcohol as it can worsen symptoms and increase drowsiness. This medication may cause dizziness and sleepiness, so avoid activities requiring mental alertness, such as driving or operating machinery, until you know how it affects you. Long-term use can lead to weak bones and mineral deficiencies (e.g., magnesium).

What happens if a dose of ISAZ 40MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should ISAZ 40MG TAB be stored?

Store ISAZ 40MG TAB at room temperature, ideally between 15°C and 30°C (59°F and 86°F). Keep it in its original container, tightly closed, and protect it from direct sunlight and moisture. Ensure it is kept out of reach of children and pets.